{"101921":{"#nid":"101921","#data":{"type":"news","title":"Magnetic nanoparticles show promise for fighting cancer","body":[{"value":"\u003Cp\u003Eby: David Terraso\n\u003C\/p\u003E\n\u003Cp\u003EScientists in the School of Biology and at the Ovarian Cancer Institute have further developed a potential new treatment against cancer that uses magnetic nanoparticles to attach to cancer cells, removing them from the body. The treatment, tested in mice in 2008, has now been tested using samples from human cancer patients. The results appear online in the journal Nanomedicine.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022We are primarily interested in developing an effective method to reduce the spread of ovarian cancer cells to other organs,\u0022 said John McDonald, professor in the School of Biology at the Georgia Institute of Technology and chief research scientist at the Ovarian Cancer Institute.\n\u003C\/p\u003E\n\u003Cp\u003EThe idea came to the research team from the work of Ken Scarberry, then a Ph.D. student at Tech. Scarberry originally conceived of the idea as a means of extracting viruses and virally infected cells. At his advisor\u0027s suggestion Scarberry began looking at how the system could work with cancer cells.\n\u003C\/p\u003E\n\u003Cp\u003EHe published his first paper on the subject in the Journal of the American Chemical Society in July 2008. In that paper he and McDonald showed that by giving the cancer cells of the mice a fluorescent green tag and staining the magnetic nanoparticles red, they were able to apply a magnet and move the green cancer cells to the abdominal region.\n\u003C\/p\u003E\n\u003Cp\u003ENow McDonald and Scarberry, currently a post-doc in McDonald\u00e2\u0080\u0099s lab, has showed that the magnetic technique works with human cancer cells.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022Often, the lethality of cancers is not attributed to the original tumor but to the establishment of distant tumors by cancer cells that exfoliate from the primary tumor,\u0022 said Scarberry. \u0022Circulating tumor cells can implant at distant sites and give rise to secondary tumors.  Our technique is designed to filter the peritoneal fluid or blood and remove these free floating cancer cells, which should increase longevity by preventing the continued metastatic spread of the cancer.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EIn tests, they showed that their technique worked as well with at capturing cancer cells from human patient samples as it did previously in mice. The next step is to test how well the technique can increase survivorship in live animal models. If that goes well, they will then test it with humans.\n\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Scientists in the School of Biology and at the Ovarian Cancer Institute have further developed a potential new treatment against cancer that uses magnetic nanoparticles to attach to cancer cells, removing them from the body. The treatment, tested in mice in 2008, has now been tested using samples from human cancer patients. The results appear online in the journal Nanomedicine.","format":"limited_html"}],"field_summary_sentence":[{"value":"Magnetic nanoparticles show promise for fighting cancer"}],"uid":"27245","created_gmt":"2010-02-22 01:00:00","changed_gmt":"2016-10-08 03:11:13","author":"Troy Hilley","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2010-02-22T00:00:00-05:00","iso_date":"2010-02-22T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"101931":{"id":"101931","type":"image","title":"Nanoparticles, in brown, attach themselves to canc","body":null,"created":"1449178166","gmt_created":"2015-12-03 21:29:26","changed":"1475894720","gmt_changed":"2016-10-08 02:45:20"}},"media_ids":["101931"],"related_links":[{"url":"http:\/\/www.biology.gatech.edu\/faculty\/john-mcdonald\/","title":"John McDonald"},{"url":"http:\/\/www.mcdonaldlab.biology.gatech.edu\/","title":"John McDonald"},{"url":"http:\/\/ovariancancerinstitute.org\/","title":"Ovarian Cancer Institute"},{"url":"http:\/\/www.biology.gatech.edu\/","title":"School of Biology"}],"groups":[{"id":"1275","name":"School of Biological Sciences"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EGeorgia Tech Media Relations\u003C\/strong\u003E\u003Cbr \/\u003ELaura Diamond\u003Cbr \/\u003E\u003Ca href=\u0022mailto:laura.diamond@comm.gatech.edu\u0022\u003Elaura.diamond@comm.gatech.edu\u003C\/a\u003E\u003Cbr \/\u003E404-894-6016\u003Cbr \/\u003EJason Maderer\u003Cbr \/\u003E\u003Ca href=\u0022mailto:maderer@gatech.edu\u0022\u003Emaderer@gatech.edu\u003C\/a\u003E\u003Cbr \/\u003E404-660-2926\u003C\/p\u003E","format":"limited_html"}],"email":["david.terraso@comm.gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}