{"158401":{"#nid":"158401","#data":{"type":"event","title":"Prof. Christopher Jaroniec, The Ohio State University","body":[{"value":"\u003Cp\u003EProf. Christopher Jaroniec, The Ohio State University\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003E\u003Cstrong\u003ESolid-state NMR spectroscopy of protein assemblies\u003C\/strong\u003E\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003ESchool Colloquium\u003C\/p\u003E\u003Cp\u003ESolid-state nuclear magnetic resonance has recently emerged as a unique spectroscopic tool, with great potential for generating atomic-resolution images of macromolecular assemblies that do not readily lend themselves to analysis by traditional high-resolution approaches. I will introduce the key aspects of magic-angle spinning solid-state NMR spectroscopy and describe the results of our recent studies aimed at providing molecular level insights into the mechanisms of fundamental biological phenomena that involve large protein-protein or protein-nucleic acid complexes, including prion and amyloid strains and transmissibility barriers linked to protein misfolding diseases as well as DNA compaction in chromatin. I will also highlight applications of this NMR methodology to the structural analysis of self-assembled organic nanomaterials formed from small molecule precursors, and discuss the development of a new class of magic-angle spinning NMR techniques for the rapid determination of protein structures in the solid phase based on the use of covalently-attached paramagnetic tags.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EFor more information contact \u003Ca href=\u0022mailto:lyon@gatech.edu\u0022\u003EProf. Andrew Lyon\u003C\/a\u003E (404-894-4090).\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EProf. Christopher Jaroniec, The Ohio State University\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003E\u003Cstrong\u003ESolid-state NMR spectroscopy of protein assemblies\u003C\/strong\u003E\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003ESchool Colloquium\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Prof. Christopher Jaroniec, The Ohio State University"}],"uid":"27275","created_gmt":"2012-10-02 08:48:56","changed_gmt":"2016-10-08 02:00:16","author":"Shirley Tomes","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2012-10-29T17:00:00-04:00","event_time_end":"2012-10-29T18:00:00-04:00","event_time_end_last":"2012-10-29T18:00:00-04:00","gmt_time_start":"2012-10-29 21:00:00","gmt_time_end":"2012-10-29 22:00:00","gmt_time_end_last":"2012-10-29 22:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/chemistry.osu.edu\/faculty\/jaroniec","title":"Prof. Christopher Jaroniec"}],"groups":[{"id":"85951","name":"School of Chemistry and Biochemistry"}],"categories":[],"keywords":[{"id":"89","name":"chemistry"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EShirley Tomes (404-894-0591) \u003Ca href=\u0022mailto:shirley.tomes@chemistry.gatech.edu\u0022\u003Eshirley.tomes@chemistry.gatech.edu\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}