{"272441":{"#nid":"272441","#data":{"type":"event","title":"Chemical Biology Seminar","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003E\u0022AApeptides: From Structure to Function\u0022\u003Cbr \/\u003E\u003Cbr \/\u003EJianfeng Cai, PhD\u003C\/strong\u003E\u003Cbr \/\u003E\u003Cstrong\u003EAssistant Professor\u003C\/strong\u003E\u003Cbr \/\u003E\u003Cstrong\u003EDepartment of Chemistry\u003C\/strong\u003E\u003Cbr \/\u003E\u003Cstrong\u003EUniversity of South Florida\u003C\/strong\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EThe identification and development of sequence-specific peptidomimetics is of significance in bioorganic chemistry and chemical biology. A new class of peptidomimetics termed \u0022AApeptides\u0022 was recently developed by our group. The synthesis of AApeptides can be conveniently achieved on the solid phase. Similar to other peptidomimetics, AApeptides are resistant to proteolytic degradation, and possess limitless potential to introduce chemically diverse functional groups. Moreover, they are able to fold into well-defined helical structures. The functions of AApeptides have also been recently explored. These include the rational design of AApeptides for the mimicry of the primary and secondary structure of bioactive peptides, as well as the development of one-bead-one-compound AApeptide combinatorial library for the identification of unnatural biomarkers or potential drug candidates.\u003Cbr \/\u003E\u003Cbr \/\u003EFaculty host:\u0026nbsp; \u003Ca href=\u0022mailto:mgfinn@gatech.edu\u0022\u003EM.G. Finn, PhD\u003C\/a\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EChemical Biology Seminar - \u0022AApeptides: From Structure to Function\u0022 - Jianfeng Cai, PhD - University of South Florida\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"\u0022AApeptides: From Structure to Function\u0022 - Jianfeng Cai, PhD - University of South Florida"}],"uid":"27195","created_gmt":"2014-01-31 11:11:26","changed_gmt":"2017-04-13 21:23:17","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2014-03-10T12:00:00-04:00","event_time_end":"2014-03-10T13:00:00-04:00","event_time_end_last":"2014-03-10T13:00:00-04:00","gmt_time_start":"2014-03-10 16:00:00","gmt_time_end":"2014-03-10 17:00:00","gmt_time_end_last":"2014-03-10 17:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/jianfengcai.myweb.usf.edu\/","title":"Cai profile website"},{"url":"http:\/\/www.chemistry.gatech.edu\/","title":"School of Chemistry and Biochemistry"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"},{"id":"65448","name":"Bioengineering Graduate Program"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78751","name":"Undergraduate students"},{"id":"78761","name":"Faculty\/Staff"},{"id":"174045","name":"Graduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:mgfinn@gatech.edu\u0022\u003EM.G. Finn, PhD\u003C\/a\u003E - faculty host\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}