{"364291":{"#nid":"364291","#data":{"type":"event","title":"Biomedical Engineering Seminar","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003E\u201c\u003C\/strong\u003E\u003Cstrong\u003ESynaptic Inhibition Controls Operating Regimes of the Cerebral Cortex in vivo\u201d\u003Cbr \/\u003E\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EBilal Haer, Ph.D.*\u003C\/strong\u003E\u003Cbr \/\u003E \u003Cstrong\u003EPost-Doctoral Fellow\u003Cbr \/\u003E University College London\u003Cbr \/\u003E Institute of Ophthalmology\u003Cbr \/\u003E Department of Visual Neuroscience\u003C\/strong\u003E\u003Cstrong\u003E\u003Cbr \/\u003E \u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003E\u003Cbr \/\u003E\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003ESeminar will be made available via videoconference in the Health Sciences Research Building, room E 182 and Technology Enterprise Park, room 104.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe cerebral cortex in vivo displays many regimes of spontaneous and sensory evoked activity.\u0026nbsp; What are the cellular and circuit mechanisms that determine these regimes? What consequences do they have for sensory processing?\u0026nbsp; And how do these mechanisms vary across behavioral states?\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;To address these questions, I will present three electrophysiological studies of spiking and sub-threshold (synaptic) activity recorded from specific cortical neuron types in vivo.\u0026nbsp; First, I will show that cortical excitation and inhibition closely balance each other during ongoing spontaneous activity.\u0026nbsp; I will next show how inhibitory circuits are engaged to produce reliable and precise cortical activity during naturalistic visual stimulation.\u0026nbsp; Finally, I will show that in the awake cortex, the specific recruitment of inhibitory circuits dramatically sharpens the spatial and temporal resolution of visual processing.\u0026nbsp; Taken together, these studies suggest a dominant role for cortical inhibitory circuits in the rapid modulation of sensory processing according to the demands of the environment and behavior.\u003C\/p\u003E\u003Cp\u003EFaculty Host: \u003Ca href=\u0022https:\/\/bme.gatech.edu\/bme\/faculty\/Christopher-Rozell\u0022\u003EChris Rozell, Ph.D.\u003C\/a\u003E\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EBiomedical Engineering Seminar - \u0022Synaptic Inhibition Controls Operating Regimes of the Cerebral Cortex in vivo\u0022 - Bilal Haider, Ph.D., University College London.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"\u0022Synaptic Inhibition Controls Operating Regimes of the Cerebral Cortex in vivo\u0022 - Bilal Haider, Ph.D. - University College London"}],"uid":"27159","created_gmt":"2015-01-14 11:58:18","changed_gmt":"2017-04-13 21:20:38","author":"Vickie Okrzesik","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2015-01-27T10:00:00-05:00","event_time_end":"2015-01-27T11:00:00-05:00","event_time_end_last":"2015-01-27T11:00:00-05:00","gmt_time_start":"2015-01-27 15:00:00","gmt_time_end":"2015-01-27 16:00:00","gmt_time_end_last":"2015-01-27 16:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"1254","name":"Wallace H. Coulter Dept. of Biomedical Engineering"}],"categories":[],"keywords":[{"id":"6175","name":"biomedical engineer"},{"id":"114591","name":"Cerebral Cortex in vivo"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78751","name":"Undergraduate students"},{"id":"78761","name":"Faculty\/Staff"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EFaculty Host: \u003Ca href=\u0022mailto:crozell13@mail.gatech.edu\u0022\u003EChris Rozell, Ph.D.\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}