{"366381":{"#nid":"366381","#data":{"type":"event","title":"Timothy Formosa, University of Utah","body":[{"value":"\u003Cp\u003EThe histone chaperone FACT and nucleosomes; some assembly required\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EThe histone chaperone FACT and nucleosomes; some assembly required\u003C\/p\u003E\u003Cp\u003EHistone chaperones bind to the abundant, basic, and hydrophobic histone proteins to prevent them from forming inappropriate interactions prior to their assembly into nucleosomes. However, chaperones also promote the assembly of nucleosomes. Structural, biochemical, and genetic results reveal how the essential histone chaperone FACT interacts with the four core histones, uncovering unexpected mechanisms for chaperone function, a previously unknown interaction motif for binding H2A-H2B dimers, and the surprisingly dynamic nature of the nucleosome itself.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Timothy Formosa, University of Utah"}],"uid":"27964","created_gmt":"2015-01-21 10:31:02","changed_gmt":"2017-04-13 21:20:34","author":"Jasmine Martin","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2015-04-30T12:00:00-04:00","event_time_end":"2015-04-30T12:00:00-04:00","event_time_end_last":"2015-04-30T12:00:00-04:00","gmt_time_start":"2015-04-30 16:00:00","gmt_time_end":"2015-04-30 16:00:00","gmt_time_end_last":"2015-04-30 16:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"1275","name":"School of Biological Sciences"}],"categories":[],"keywords":[{"id":"115281","name":"Timothy Formosa"},{"id":"9552","name":"Yuhong Fan"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1793","name":"Sports\/Athletics"}],"invited_audience":[{"id":"78751","name":"Undergraduate students"},{"id":"78761","name":"Faculty\/Staff"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EIf you have questions about logistics or would like to set up an appointment with the speaker, please contact the School of Biology\u0027s administrative office at \u003Ca href=\u0022mailto:bio-admin@biology.gatech.edu\u0022\u003Ebio-admin@biology.gatech.edu\u003C\/a\u003E.\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}