{"372321":{"#nid":"372321","#data":{"type":"event","title":"MS Defense Presentation by Josh Grooms","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EJosh Grooms\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003EBME MS Defense Presentation\u003C\/p\u003E\u003Cp\u003EMonday February 9, 2015 at 1:00 \u2013 3:00 PM\u003C\/p\u003E\u003Cp\u003EEmory University, Health Sciences Research Building \u2013 Rollins Auditorium (First Floor)\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EAdvisor: \u003C\/strong\u003EShella Keilholz, PhD\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ECommittee Members:\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003EShella Keilholz, PhD\u003C\/p\u003E\u003Cp\u003EXiaoping Hu, PhD\u003C\/p\u003E\u003Cp\u003ECharles Epstein, MD\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ETitle: Examining the Relationship between BOLD fMRI and Infraslow EEG in the Resting Human Brain\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EAbstract:\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003E\u0026nbsp;\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003EFunctional magnetic resonance imaging (fMRI) is currently at the forefront of research on cognition and the brain\u2019s large-scale organization. Patterns found in the hemodynamic signals that it records have been strongly linked to various behaviors and cognitive pathologies. These signals are widely assumed to reflect local neuronal activity, but our understanding of the exact relationship between them remains incomplete. To address this, researchers use multimodal approaches that pair fMRI signals with known measures of neuronal activity, such as electroencephalography (EEG). It has long been thought that the infraslow (\u0026lt; 0.1 Hz) fMRI signals, which have become so important to the study of brain function, might have a direct electrophysiological counterpart. If so, the impact could be substantial; EEG could be positioned as a low-cost alternative to fMRI when fMRI is impractical. Additionally, with its wide availability and high temporal resolution, EEG could become much more influential in the studying of functional brain networks. Previous studies have produced indirect support for the fMRI-EEG relationship, but until recently the hypothesized link between their infraslow signals had not been tested in humans. The objective of this study was to investigate and characterize this link by examining infraslow fMRI and EEG signals that were simultaneously recorded in resting human adults. We present evidence strongly favoring the link by demonstrating significant stationary and dynamic correlations between the two signal types. Moreover, functional brain networks appear to be a fundamental unit of this coupling. We conclude that infraslow electrophysiology is likely playing an important role in the dynamic configuration of the resting state brain networks that are well-known in fMRI research. Our results provide new insights into the neuronal underpinnings of hemodynamic activity and a foundational point on which the use of infraslow EEG in functional connectivity studies can be based.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Examining the Relationship between BOLD fMRI and Infraslow EEG in the Resting Human Brain"}],"uid":"27707","created_gmt":"2015-02-03 16:36:00","changed_gmt":"2016-10-08 01:45:55","author":"Tatianna Richardson","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2015-02-09T12:00:00-05:00","event_time_end":"2015-02-09T14:00:00-05:00","event_time_end_last":"2015-02-09T14:00:00-05:00","gmt_time_start":"2015-02-09 17:00:00","gmt_time_end":"2015-02-09 19:00:00","gmt_time_end_last":"2015-02-09 19:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"221981","name":"Graduate Studies"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[{"id":"78771","name":"Public"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}