{"523751":{"#nid":"523751","#data":{"type":"event","title":"BME Seminar Speaker: Steven Nicoll","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003ESteven B. Nicoll, Ph.D.\u003C\/strong\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EAssociate Professor\u003Cbr \/\u003EConnective Tissue Engineering Laboratory\u003Cbr \/\u003EDepartment of Biomedical Engineering\u003Cbr \/\u003EThe City College of New York\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cstrong\u003ETuesday, April 26\u003Cbr \/\u003E11:00 a.m.\u003Cbr \/\u003EU.A. Whitaker, Room 1103\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EABSTRACT\u003C\/strong\u003E\u003Cbr \/\u003EThere are several indications for the use of permanent fillers for volumetric augmentation, including the correction of localized tissue atrophy and deficits due to trauma, tumor resections, infectious processes (i.e., HIV infection), and congenital craniofacial anomalies. In addition, injury and degeneration of specialized connective tissues, such as those found in the intervertebral disc of the spinal column, require surgical intervention to restore function. Tissue engineering strategies may provide novel replacement therapies for such damaged or diseased soft tissues.\u0026nbsp; However, there remains a need for biomaterials that are effective, biocompatible, renewable, and inexpensive. Potential candidates include derivatives of the plant polysaccharide, cellulose, which may be chemically modified to create injectable, in situ gelling materials with tunable properties tailored for specific clinical applications.\u0026nbsp; These hydrogels may be used alone or in combination with mesenchymal stem cells to engineer viable tissue analogs. This seminar will focus on the design of these cellulosic materials, considering multiple factors such as anatomical site and FDA regulatory pathways, to guide the research and development process toward eventual clinical translation.\u003C\/p\u003E\u003Cp\u003E\u003Cbr \/\u003E\u003C\/p\u003E\u003Cp\u003EHost: \u003Ca href=\u0022mailto:%20johnna.temenoff@bme.gatech.edu\u0022\u003EJohnna Temenoff, Ph.D.\u003C\/a\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Development of Injectable Cellulosic Hydrogels for Soft Tissue Replacement"}],"uid":"27513","created_gmt":"2016-04-12 15:35:06","changed_gmt":"2017-04-13 21:16:00","author":"Walter Rich","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2016-04-26T12:00:00-04:00","event_time_end":"2016-04-26T13:00:00-04:00","event_time_end_last":"2016-04-26T13:00:00-04:00","gmt_time_start":"2016-04-26 16:00:00","gmt_time_end":"2016-04-26 17:00:00","gmt_time_end_last":"2016-04-26 17:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"1254","name":"Wallace H. Coulter Dept. of Biomedical Engineering"}],"categories":[],"keywords":[{"id":"168549","name":"Nicolls"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78751","name":"Undergraduate students"},{"id":"78761","name":"Faculty\/Staff"},{"id":"174045","name":"Graduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EJohnna Temenoff, Ph.D.\u003Cbr \/\u003E\u003Ca href=\u0022mailto:johnna.temenoff@bme.gatech.edu\u0022\u003Ejohnna.temenoff@bme.gatech.edu\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}