{"56203":{"#nid":"56203","#data":{"type":"event","title":"ChBE Fall Seminar Series (August 29, 2007)","body":[{"value":"\u003Cp\u003EKristi Anseth, Tisone Professor, Associate Professor of Surgery, and Howard Hughes Medical Institute Investigator at the University of Colorado at Boulder, presents Permitting vs. Promoting Hydrogel Niches for Tissue Regeneration as part of ChBE\u0027s Fall Seminar Series.\n\u003C\/p\u003E\n\u003Cp\u003EUnless otherwise noted, all seminars are held in the Molecular Science and Engineering Building in Room G011. Refreshments are served at 3:30 PM. The seminar starts promptly at 4:00 PM.\n\u003C\/p\u003E\n\u003Cp\u003EABSTRACT:\u003Cbr \/\u003E\nHydrogels provide a unique, largely aqueous environment for 3D cell culture, and when locally\u003Cbr \/\u003E\nmodified with appropriate signaling molecules, these synthetic niches can facilitate the\u003Cbr \/\u003E\nregeneration of tissues. While the gel environment is often \u0026gt;90% water, the microscopic\u003Cbr \/\u003E\narchitecture and local chemistry play important roles in dictating cell morphology, proliferation,\u003Cbr \/\u003E\nand differentiation; gel degradation and erosion; and the secretion and distribution of\u003Cbr \/\u003E\nextracellular matrix molecules. This talk will illustrate several examples where the\u003Cbr \/\u003E\nregeneration of neotissue structures is highly coupled to the biophysical and biochemical\u003Cbr \/\u003E\nproperties of the gels, and demonstrate how appropriate tuning of the gel properties can create\u003Cbr \/\u003E\nmicroenvironments that simply permit cells to function to those that actively promote specific\u003Cbr \/\u003E\ncell functions. Integral to this understanding is the ability to manipulate the underlying gel\u003Cbr \/\u003E\nchemistry and properties through the synthesis of macromolecular precursors and control of the\u003Cbr \/\u003E\ngelation process.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Kristi Anseth, Tisone Professor, Associate Professor of Surgery, and Howard Hughes Medical Institute Investigator at the University of Colorado at Boulder, presents a seminar...","format":"limited_html"}],"field_summary_sentence":[{"value":"Kristi Anseth presents seminar"}],"uid":"27255","created_gmt":"2010-05-20 11:46:59","changed_gmt":"2016-10-08 01:51:37","author":"Josie Giles","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2007-08-29T16:30:00-04:00","event_time_end":"2007-08-29T18:00:00-04:00","event_time_end_last":"2007-08-29T18:00:00-04:00","gmt_time_start":"2007-08-29 20:30:00","gmt_time_end":"2007-08-29 22:00:00","gmt_time_end_last":"2007-08-29 22:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/www.chbe.gatech.edu\/","title":"School of Chemical \u0026 Biomolecular Engineering"}],"groups":[{"id":"1240","name":"School of Chemical and Biomolecular Engineering"}],"categories":[],"keywords":[{"id":"1303","name":"chbe"},{"id":"1704","name":"chemical \u0026 biomolecular engineering"},{"id":"560","name":"chemical engineering"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1789","name":"Conference\/Symposium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EJosie Giles\u003C\/strong\u003E\u003Cbr \/\u003ESchool of Chemical \u0026amp; Biomolecular Engineering\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=jg234\u0022\u003EContact Josie Giles\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-2299\u003C\/strong\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}