{"598090":{"#nid":"598090","#data":{"type":"news","title":"Toward Personalized Treatment of Cystic Fibrosis","body":[{"value":"\u003Cp\u003ECystic fibrosis (CF) is a debilitating genetic disease that impairs lung function. A major consequence of the disease is establishment of chronic lung infections. Multiple bacterial species cause the infections, and the bacterial populations differ from patient to patient.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EResearch by School of Biological Sciences Associate Professor \u003Ca href=\u0022http:\/\/biosci.gatech.edu\/people\/sam-brown\u0022\u003ESam Brown\u003C\/a\u003E aims to understand the dynamics of the bacterial populations \u0026ndash; or microbiomes \u0026ndash; associated with the disease. The hope is to develop treatments targeting the specific microbiomes of individual patients.\u003C\/p\u003E\r\n\r\n\u003Cp\u003ETo this end, the Centers for Disease Control and Prevention (CDC) has awarded Brown a grant of $300,000 for one year to develop new treatment strategies that are tailored to the individual microbiome profile of a person with cystic fibrosis. \u003Ca href=\u0022https:\/\/www.cdc.gov\/drugresistance\/solutions-initiative\/innovations-to-slow-AR.html\u0022\u003EBrown is one of 25 investigators to receive funding from CDC\u003C\/a\u003E as part of the agency\u0026rsquo;s push to combat antibiotic resistance.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EThe project \u0026ndash; titled \u0026ldquo;Optimization of Therapeutic Strategies to Manage Polymicrobial CF Lung Infections: Clinical Assessment \u0026ndash;will be carried out with co-investigator \u003Ca href=\u0022http:\/\/www.pediatrics.emory.edu\/information\/employee\/ourpeople.php?id=641\u0022\u003EArlene Stecenko\u003C\/a\u003E, a cystic fibrosis expert at Emory University School of Medicine. Brown and Stecenko will track infection microbiomes in a small group of patients. They will monitor the impact of existing antibiotic treatments. They also will explore whether patients who naturally carry candidate \u0026ldquo;probiotic,\u0026rdquo; or beneficial, species are more resistant to colonization by notorious pathogens such as \u003Cem\u003EPseudomonas aeruginosa \u003C\/em\u003Eand \u003Cem\u003EStaphylococcus aureus\u003C\/em\u003E.\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026ldquo;This funding takes us closer to the long-term goal of effective personalized-medicine solutions to improve the lives of people with cystic fibrosis,\u0026rdquo; says Brown, who is a researcher with the Petit Institute for Bioengineering and Bioscience.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"Georgia Tech\u2019s Sam Brown Receives CDC Grant to Develop Treatment Strategies"}],"field_summary":[{"value":"\u003Cp\u003ESam Brown\u0026nbsp;aims to understand the dynamics of the bacterial populations \u0026ndash; or microbiomes \u0026ndash; associated with cystic fibrosis to develop treatments targeting the specific microbiomes of individual patients.\u003C\/p\u003E\r\n","format":"limited_html"}],"field_summary_sentence":[{"value":"The grant will advance efforts to personalize the treatment of cystic fibrosis."}],"uid":"30678","created_gmt":"2017-10-30 18:24:06","changed_gmt":"2017-11-06 17:47:33","author":"A. Maureen Rouhi","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2017-10-30T00:00:00-04:00","iso_date":"2017-10-30T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"598089":{"id":"598089","type":"image","title":"Sam Brown","body":null,"created":"1509387508","gmt_created":"2017-10-30 18:18:28","changed":"1509387508","gmt_changed":"2017-10-30 18:18:28","alt":"","file":{"fid":"228012","name":"Sam.Brown_.sam_lab_0.jpg","image_path":"\/sites\/default\/files\/images\/Sam.Brown_.sam_lab_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/Sam.Brown_.sam_lab_0.jpg","mime":"image\/jpeg","size":46932,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/Sam.Brown_.sam_lab_0.jpg?itok=IlLE3FfH"}},"598088":{"id":"598088","type":"image","title":"Centers for Disease Control and Prevention","body":null,"created":"1509387430","gmt_created":"2017-10-30 18:17:10","changed":"1509387430","gmt_changed":"2017-10-30 18:17:10","alt":"","file":{"fid":"228011","name":"CDC logo.gif","image_path":"\/sites\/default\/files\/images\/CDC%20logo.gif","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/CDC%20logo.gif","mime":"image\/gif","size":8175,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/CDC%20logo.gif?itok=0m5ncFHG"}}},"media_ids":["598089","598088"],"groups":[{"id":"1278","name":"College of Sciences"},{"id":"85951","name":"School of Chemistry and Biochemistry"}],"categories":[{"id":"138","name":"Biotechnology, Health, Bioengineering, Genetics"}],"keywords":[{"id":"7478","name":"cystic fibrosis"},{"id":"174114","name":"microbiomes"},{"id":"126571","name":"go-PetitInstitute"},{"id":"167225","name":"Sam Brown"},{"id":"166882","name":"School of Biological Sciences"},{"id":"4896","name":"College of Sciences"}],"core_research_areas":[{"id":"39441","name":"Bioengineering and Bioscience"}],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EA. Maureen Rouhi, Ph.D.\u003Cbr \/\u003E\r\nDirector of Communications\u003Cbr \/\u003E\r\nCollege of Sciences\u003C\/p\u003E\r\n","format":"limited_html"}],"email":["maureen.rouhi@cos.gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}