{"601210":{"#nid":"601210","#data":{"type":"event","title":"MS defense by Taylor James","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EName: Taylor James\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EMaster\u0026rsquo;s Thesis Defense Meeting\u003Cbr \/\u003E\r\n\u003Cstrong\u003EDate:\u003C\/strong\u003E\u0026nbsp;Wednesday, January 24, 2018\u003Cbr \/\u003E\r\n\u003Cstrong\u003ETime:\u003C\/strong\u003E\u0026nbsp;2:00pm\u003Cbr \/\u003E\r\n\u003Cstrong\u003ELocation:\u0026nbsp;\u003C\/strong\u003ECABI Conference Room\u003Cbr \/\u003E\r\n\u0026nbsp;\u003Cbr \/\u003E\r\n\u003Cstrong\u003EAdvisor:\u003C\/strong\u003E\u003Cbr \/\u003E\r\nProfessor Audrey Duarte, Ph.D. (Georgia Tech)\u003Cbr \/\u003E\r\n\u0026nbsp;\u003Cbr \/\u003E\r\n\u003Cstrong\u003EThesis Committee Members:\u003C\/strong\u003E\u003Cbr \/\u003E\r\nProfessor Audrey Duarte, Ph.D. (Georgia Tech)\u003C\/p\u003E\r\n\r\n\u003Cp\u003EProfessor Eric Schumacher, Ph.D. (Georgia Tech)\u003Cbr \/\u003E\r\nProfessor Mark Wheeler, Ph.D. (Georgia Tech)\u003Cbr \/\u003E\r\n\u0026nbsp;\u003Cbr \/\u003E\r\n\u003Cstrong\u003ETitle:\u003C\/strong\u003E\u0026nbsp;Separating Contributions of\u0026nbsp;Prefrontal Cortex\u0026nbsp;Subregions\u0026nbsp;to Age-Related Associative Memory Impairments\u003Cbr \/\u003E\r\n\u003Cstrong\u003EAbstract\u003C\/strong\u003E\u003Cbr \/\u003E\r\nThe anterior prefrontal cortex (aPFC) is believed to play a critical\u0026nbsp;role in integrating the outputs of lower-order\u0026nbsp;processes, such as evaluations\u0026nbsp;of item or inter-item properties. The high-order integration functions\u0026nbsp;attributed to the\u0026nbsp;aPFC have been shown to support complex reasoning. but the\u0026nbsp;region\u0026rsquo;s role in episodic encoding is less well\u0026nbsp;understood. Emerging data\u0026nbsp;suggest high-order PFC functions may be particularly susceptible to the effects\u0026nbsp;of age and\u0026nbsp;may contribute to older adults\u0026rsquo; associative memory impairments. It\u0026nbsp;is currently unknown how aging interferes with\u0026nbsp;aPFC operations necessary for\u0026nbsp;integrating multiple relations for episodic encoding and retrieval. We\u0026nbsp;investigated this\u0026nbsp;issue in the current fMRI study. Young and older adults were\u0026nbsp;presented with an occupation and an object and were\u0026nbsp;asked to judge how likely\u0026nbsp;the two were to interact, either in general or within the context of a given\u0026nbsp;scene. When\u0026nbsp;provided with a scene, participants needed to consider and\u0026nbsp;integrate the distinct relations between the three items to\u0026nbsp;reach a decision: a\u0026nbsp;task dependent on aPFC functions. fMRI data were collected during encoding, and\u0026nbsp;memory for\u0026nbsp;object-occupation pairings and their associated contexts was tested\u0026nbsp;outside of the scanner. fMRI results showed\u0026nbsp;greater left DLPFC activity with\u0026nbsp;increasing integration demands for both young and older adults. Older adults\u0026nbsp;exhibited\u0026nbsp;memory impairments for both the pairs and contexts, despite similar engagement\u0026nbsp;of aPFC regions as the young. This\u0026nbsp;could indicate that integration processes\u0026nbsp;were intact yet inefficient in older adults. Alternatively, performance deficits\u0026nbsp;may have resulted from age-related differences in whole-brain patterns of\u0026nbsp;task-related encoding activity.\u0026nbsp;\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Separating Contributions of Prefrontal Cortex Subregions to Age-Related Associative Memory Impairments"}],"uid":"27707","created_gmt":"2018-01-23 17:49:29","changed_gmt":"2018-01-23 17:49:29","author":"Tatianna Richardson","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2018-01-24T14:00:00-05:00","event_time_end":"2018-01-24T16:00:00-05:00","event_time_end_last":"2018-01-24T16:00:00-05:00","gmt_time_start":"2018-01-24 19:00:00","gmt_time_end":"2018-01-24 21:00:00","gmt_time_end_last":"2018-01-24 21:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"221981","name":"Graduate Studies"}],"categories":[],"keywords":[{"id":"111531","name":"ms defense"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}