{"64226":{"#nid":"64226","#data":{"type":"external_news","title":"Flu Vaccine Patch to get 5-Year Test","body":[{"value":"\u003Cp\u003EA revolutionary flu vaccine patch is likely to be developed in the course of an upcoming 5-year clinical trial.\n\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27195","created_gmt":"2011-02-14 13:35:58","changed_gmt":"2016-10-08 02:24:18","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","publication":"David Wright","field_article_url":"","publication_url":"http:\/\/drugtopics.modernmedicine.com\/drugtopics\/Modern+Medicine+Now\/Flu-vaccine-patch-to-get-5-year-test\/ArticleStandard\/Article\/detail\/707274?contextCategoryId=40152","dateline":{"date":"2011-02-15T00:00:00-05:00","iso_date":"2011-02-15T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"140","name":"Cancer Research"},{"id":"132","name":"Institute Leadership"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"}],"keywords":[{"id":"11896","name":"A revolutionary flu vaccine patch is likely to be developed in the course of an upcoming 5-year clinical trial"},{"id":"109","name":"Georgia Tech"},{"id":"248","name":"IBB"},{"id":"495","name":"Mark Prausnitz"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"65062":{"#nid":"65062","#data":{"type":"external_news","title":"Give yourself the flu vaccine?","body":[{"value":"\u003Cp\u003E For some people, getting a flu shot can be a traumatizing experience, especially children.\u0026nbsp; That\u0027s why researchers at Georgia Tech and Emory University are collaborating on a more patient-friendly way to vaccinate.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27195","created_gmt":"2011-03-22 10:18:03","changed_gmt":"2016-10-08 02:24:21","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","publication":"PACE-ICE PACE","field_article_url":"","publication_url":"http:\/\/abclocal.go.com\/wpvi\/story?section=news\/health\u0026id=8023493","dateline":{"date":"2011-03-20T00:00:00-04:00","iso_date":"2011-03-20T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"140","name":"Cancer Research"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"}],"keywords":[{"id":"12431","name":"Give yourself the flu vaccine?"},{"id":"248","name":"IBB"},{"id":"495","name":"Mark Prausnitz"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"60106":{"#nid":"60106","#data":{"type":"news","title":"Patch heralds new era in battle against pandemics","body":[{"value":"\u003Cp\u003EA revolutionary way of vaccinating against infectious diseases has been invented by scientists who have developed a skin patch containing an influenza vaccine.\n\u003C\/p\u003E\n\u003Cp\u003EThe patch does away with needles and syringes and could transform the battle against future pandemics by painlessly inoculating patients with vaccines that could be sent out in the post and self-administered in the home by somebody with no medical experience. \n\u003C\/p\u003E\n\u003Cp\u003EIn the developing world, the skin patches could eliminate the need for the costly medical infrastructure of mass-vaccination campaigns, which require trained medical personnel to inject vaccines, and expensive storage equipment. Skin patches also bypass the hazards of dirty needles. \n\u003C\/p\u003E\n\u003Cp\u003EThe skin patch is \u0022armed\u0022 with an array of microscopic needles made of biodegradable plastic that painlessly scratch the surface of the skin and dissolve harmlessly without trace after delivering the vaccine safely inside the body.\n\u003C\/p\u003E\n\u003Cp\u003ETo view full article, visit URL below: \n\u003C\/p\u003E\n\u003Cp\u003E\u003Ca href=\u0022http:\/\/www.independent.co.uk\/news\/science\/patch-heralds-new-era-in-battle-against-pandemics-2029750.html\u0022 title=\u0022http:\/\/www.independent.co.uk\/news\/science\/patch-heralds-new-era-in-battle-against-pandemics-2029750.html\u0022\u003Ehttp:\/\/www.independent.co.uk\/news\/science\/patch-heralds-new-era-in-battl...\u003C\/a\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"A revolutionary way of vaccinating against infectious diseases has been invented by scientists who have developed a skin patch containing an influenza vaccine.","format":"limited_html"}],"field_summary_sentence":[{"value":"Scientists unveil an innovative and cheap method of delivering v"}],"uid":"27349","created_gmt":"2010-07-19 00:00:00","changed_gmt":"2016-10-08 03:07:11","author":"Floyd Wood","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2010-07-19T00:00:00-04:00","iso_date":"2010-07-19T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"60107":{"id":"60107","type":"image","title":"Prof. Mark Prausnitz","body":null,"created":"1449176253","gmt_created":"2015-12-03 20:57:33","changed":"1475894520","gmt_changed":"2016-10-08 02:42:00"}},"media_ids":["60107"],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"140","name":"Cancer Research"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"}],"keywords":[{"id":"109","name":"Georgia Tech"},{"id":"248","name":"IBB"},{"id":"495","name":"Mark Prausnitz"},{"id":"7496","name":"microneedles"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EFloyd Wood\u003C\/strong\u003E\u003Cbr \/\u003EIBB\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=fwood3\u0022\u003EContact Floyd Wood\u003C\/a\u003E","format":"limited_html"}],"email":["floyd.wood@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"60104":{"#nid":"60104","#data":{"type":"news","title":"Microneedles May Make Getting Flu Shots Easier","body":[{"value":"\u003Cp\u003EOne day your annual flu shot could come in the mail.\n\u003C\/p\u003E\n\u003Cp\u003EAt least that\u0027s the hope of researchers developing a new method of vaccine delivery that people could even use at home: a patch with microneedles.\n\u003C\/p\u003E\n\u003Cp\u003EMicroneedles?\n\u003C\/p\u003E\n\u003Cp\u003EThat\u0027s right, tiny little needles so small you don\u0027t even feel them. Attached to a patch like a Band-Aid, the little needles barely penetrate the skin before they dissolve and release their vaccine.\n\u003C\/p\u003E\n\u003Cp\u003EResearchers led by Mark Prausnitz of Georgia Institute of Technology reported their research on microneedles in Sunday\u0027s edition of Nature Medicine.\n\u003C\/p\u003E\n\u003Cp\u003EThe business side of the patch feels like fine sandpaper, he said. In tests of microneedles without vaccine, people rated the discomfort at one-tenth to one-twentieth that of getting a standard injection, he said. Nearly everyone said it was painless.\n\u003C\/p\u003E\n\u003Cp\u003EVisit URL below to view full NPR article:\n\u003C\/p\u003E\n\u003Cp\u003E\u003Ca href=\u0022http:\/\/www.npr.org\/templates\/story\/story.php?storyId=128603588\u0022 title=\u0022http:\/\/www.npr.org\/templates\/story\/story.php?storyId=128603588\u0022\u003Ehttp:\/\/www.npr.org\/templates\/story\/story.php?storyId=128603588\u003C\/a\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EOne day your annual flu shot could come in the mail.\n\nAt least that\u0027s the hope of researchers developing a new method of vaccine delivery that people could even use at home: a patch with microneedles.\n\nMicroneedles?\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Microneedles May Make Getting Flu Shots Easier"}],"uid":"27349","created_gmt":"2010-07-19 00:00:00","changed_gmt":"2016-10-08 03:07:11","author":"Floyd Wood","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2010-07-18T00:00:00-04:00","iso_date":"2010-07-18T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"60107":{"id":"60107","type":"image","title":"Prof. Mark Prausnitz","body":null,"created":"1449176253","gmt_created":"2015-12-03 20:57:33","changed":"1475894520","gmt_changed":"2016-10-08 02:42:00"}},"media_ids":["60107"],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"140","name":"Cancer Research"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"}],"keywords":[{"id":"109","name":"Georgia Tech"},{"id":"248","name":"IBB"},{"id":"495","name":"Mark Prausnitz"},{"id":"7496","name":"microneedles"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EFloyd Wood\u003C\/strong\u003E\u003Cbr \/\u003EIBB\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=fwood3\u0022\u003EContact Floyd Wood\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["floyd.wood@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"60096":{"#nid":"60096","#data":{"type":"news","title":"Vaccine-Delivery Patch with Dissolving Microneedles Boosts Protection","body":[{"value":"\u003Cp\u003EA new vaccine-delivery patch based on hundreds of microscopic needles that dissolve into the skin could allow persons without medical training to painlessly administer vaccines -- while providing improved immunization against diseases such as influenza.\u003C\/p\u003E\u003Cp\u003EPatches containing micron-scale needles that carry vaccine with them as they dissolve into the skin could simplify immunization programs by eliminating the use of hypodermic needles -- and their \u0022sharps\u0022 disposal and re-use concerns. Applied easily to the skin, the microneedle patches could allow self-administration of vaccine during pandemics and simplify large-scale immunization programs in developing nations. \u003C\/p\u003E\u003Cp\u003EDetails of the dissolving microneedle patches and immunization benefits observed in experimental mice were reported July 18th in the advance online publication of the journal \u003Cem\u003ENature Medicine\u003C\/em\u003E. Conducted by researchers from Emory University and the Georgia Institute of Technology, the study is believed to be the first to evaluate the immunization benefits of dissolving microneedles. The research was supported by the National Institutes of Health (NIH). \u003C\/p\u003E\u003Cp\u003E\u0022In this study, we have shown that a dissolving microneedle patch can vaccinate against influenza at least as well, and probably better than, a traditional hypodermic needle,\u0022 said Mark Prausnitz, a professor in the Georgia Tech School of Chemical and Biomolecular Engineering. \u003C\/p\u003E\u003Cp\u003EJust 650 microns in length and assembled into an array of 100 needles for the mouse study, the dissolving microneedles penetrate the outer layers of skin. Beyond their other advantages, the dissolving microneedles appear to provide improved immunity to influenza when compared to vaccination with hypodermic needles. \u003C\/p\u003E\u003Cp\u003E\u0022The skin is a particularly attractive site for immunization because it contains an abundance of the types of cells that are important in generating immune responses to vaccines,\u0022 said Richard Compans, professor of microbiology and immunology at Emory University School of Medicine. \u003C\/p\u003E\u003Cp\u003EIn the study, one group of mice received the influenza vaccine using traditional hypodermic needles injecting into muscle; another group received the vaccine through dissolving microneedles applied to the skin, while a control group had microneedle patches containing no vaccine applied to their skin. When infected with influenza virus 30 days later, both groups that had received the vaccine remained healthy while mice in the control group contracted the disease and died. \u003C\/p\u003E\u003Cp\u003EThree months after vaccination, the researchers also exposed a different group of immunized mice to flu virus and found that animals vaccinated with microneedles appeared to have a better \u0022recall\u0022 response to the virus and thus were able to clear the virus from their lungs more effectively than those that received vaccine with hypodermic needles. \u003C\/p\u003E\u003Cp\u003E\u0022Another advantage of these microneedles is that the vaccine is present as a dry formulation, which will enhance its stability during distribution and storage,\u0022 said Ioanna Skountzou, an Emory University assistant professor. \u003C\/p\u003E\u003Cp\u003EPressed into the skin, the microneedles quickly dissolve in bodily fluids, leaving only the water-soluble backing. The backing can be discarded because it no longer contains any sharps. \u003C\/p\u003E\u003Cp\u003E\u0022We envision people getting the patch in the mail or at a pharmacy and then self administering it at home,\u0022 said Sean Sullivan, the study\u2019s lead author from Georgia Tech. \u0022Because the microneedles on the patch dissolve away into the skin, there would be no dangerous sharp needles left over.\u0022 \u003C\/p\u003E\u003Cp\u003EThe microneedle arrays were made from a polymer material, poly-vinyl pyrrolidone, that has been shown to be safe for use in the body. Freeze-dried vaccine was mixed with the vinyl-pyrrolidone monomer before being placed into microneedle molds and polymerized at room temperature using ultraviolet light. \u003C\/p\u003E\u003Cp\u003EIn many parts of the world, poor medical infrastructure leads to the re-use of hypodermic needles, contributing to the spread of diseases such as HIV and hepatitis B. Dissolving microneedle patches would eliminate re-use while allowing vaccination to be done by personnel with minimal training. \u003C\/p\u003E\u003Cp\u003EThough the study examined only the administration of flu vaccine with the dissolving microneedles, the technique should be useful for other immunizations. If mass-produced, the microneedle patches are expected to cost about the same as conventional needle-and-syringe techniques, and may lower the overall cost of immunization programs by reducing personnel costs and waste disposal requirements, Prausnitz said. \u003C\/p\u003E\u003Cp\u003EBefore dissolving microneedles can be made widely available, however, clinical studies will have to be done to assure safety and effectiveness. Other vaccine formulation techniques may also be studied, and researchers will want to better understand why vaccine delivery with dissolving microneedles has been shown to provide better protection. \u003C\/p\u003E\u003Cp\u003EBeyond those already mentioned, the study involved Jeong-Woo Lee, Vladimir Zarnitsyn, Seong-O Choi and Niren Murthy from Georgia Tech, and Dimitrios Koutsonanos and Maria del Pilar Martin from Emory University. \u003C\/p\u003E\u003Cp\u003E\u0022The dissolving microneedle patch could open up many new doors for immunization programs by eliminating the need for trained personnel to carry out the vaccination,\u0022 Prausnitz said. \u0022This approach could make a significant impact because it could enable self-administration as well as simplify vaccination programs in schools and assisted living facilities.\u0022 \u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003EGeorgia Institute of Technology\u003Cbr \/\u003E75 Fifth Street, N.W., Suite 314\u003Cbr \/\u003EAtlanta, Georgia 30308 USA\u003C\/strong\u003E \u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EMedia Relations Contacts\u003C\/strong\u003E: John Toon, Georgia Tech (404-894-6986) (\u003Ca href=\u0022mailto:jtoon@gatech.edu\u0022\u003Ejtoon@gatech.edu\u003C\/a\u003E), Holly Korschun, Emory University (404-727-3990) (\u003Ca href=\u0022mailto:hkorsch@emory.edu\u0022\u003Ehkorsch@emory.edu\u003C\/a\u003E) or Abby Vogel Robinson, Georgia Tech (404-385-3364) (\u003Ca href=\u0022mailto:abby@innovate.gatech.edu\u0022\u003Eabby@innovate.gatech.edu\u003C\/a\u003E). \u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EWriter\u003C\/strong\u003E: John Toon \u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"Device Replaces Hypodermic Needles to Eliminate Sharp Waste"}],"field_summary":[{"value":"\u003Cp\u003EA new vaccine-delivery patch based on hundreds of microscopic needles that dissolve into the skin could allow persons without medical training to painlessly administer vaccines \u2013 while providing improved immunization against diseases such as influenza.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Dissolving microneedles offer a new vaccine-delivery solution"}],"uid":"27303","created_gmt":"2010-07-18 00:00:00","changed_gmt":"2016-10-08 03:07:11","author":"John Toon","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2010-07-18T00:00:00-04:00","iso_date":"2010-07-18T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"60097":{"id":"60097","type":"image","title":"Dissolving microneedles on fingertip","body":null,"created":"1449176239","gmt_created":"2015-12-03 20:57:19","changed":"1475894520","gmt_changed":"2016-10-08 02:42:00","alt":"Dissolving microneedles on fingertip","file":{"fid":"191051","name":"tvn90868.jpg","image_path":"\/sites\/default\/files\/images\/tvn90868_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tvn90868_0.jpg","mime":"image\/jpeg","size":428627,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tvn90868_0.jpg?itok=XnfaXzLx"}},"60098":{"id":"60098","type":"image","title":"Dissolving microneedles on application.","body":null,"created":"1449176239","gmt_created":"2015-12-03 20:57:19","changed":"1475894520","gmt_changed":"2016-10-08 02:42:00","alt":"Dissolving microneedles on application.","file":{"fid":"191052","name":"tvw90868.jpg","image_path":"\/sites\/default\/files\/images\/tvw90868_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tvw90868_0.jpg","mime":"image\/jpeg","size":534894,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tvw90868_0.jpg?itok=0nHMgk9n"}},"60099":{"id":"60099","type":"image","title":"Dissolving microneedles after on minute.","body":null,"created":"1449176239","gmt_created":"2015-12-03 20:57:19","changed":"1475894520","gmt_changed":"2016-10-08 02:42:00","alt":"Dissolving microneedles after on minute.","file":{"fid":"191053","name":"tjx90868.jpg","image_path":"\/sites\/default\/files\/images\/tjx90868_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tjx90868_0.jpg","mime":"image\/jpeg","size":603655,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tjx90868_0.jpg?itok=LDwBMIKz"}}},"media_ids":["60097","60098","60099"],"related_links":[{"url":"http:\/\/www.chbe.gatech.edu\/fac_staff\/faculty\/prausnitz.php","title":"Mark Prausnitz"},{"url":"http:\/\/microbiology.emory.edu\/compans_r.html","title":"Richard Compans"},{"url":"http:\/\/www.chbe.gatech.edu\/","title":"School of Chemical \u0026 Biomolecular Engineering"},{"url":"http:\/\/www.med.emory.edu\/","title":"Emory University School of Medicine"}],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"145","name":"Engineering"},{"id":"147","name":"Military Technology"},{"id":"135","name":"Research"}],"keywords":[{"id":"296","name":"Flu"},{"id":"764","name":"immunization"},{"id":"765","name":"influenza"},{"id":"494","name":"Microneedle"},{"id":"170850","name":"skin"},{"id":"763","name":"vaccine"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EJohn Toon\u003C\/strong\u003E\u003Cbr \/\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=jt7\u0022\u003EContact John Toon\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-6986\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["jtoon@gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"57750":{"#nid":"57750","#data":{"type":"news","title":"Mark Prausnitz presents the Medtronic Lecture at Oxford","body":[{"value":"\u003Cp\u003EMark Prausnitz, PhD. presents the Medtronic Lecture in Biomedical Engineering at the University of Oxford, United Kingdom, on June 2, 2010.\n\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Mark Prausnitz, PhD. presents the Medtronic Lecture in Biomedical Engineering at the University of Oxford, United Kingdom, on June 2","format":"limited_html"}],"field_summary_sentence":[{"value":"Mark Prausnitz presents the Medtronic Lecture at Oxford"}],"uid":"27349","created_gmt":"2010-06-01 00:00:00","changed_gmt":"2016-10-08 03:06:39","author":"Floyd Wood","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2010-06-01T00:00:00-04:00","iso_date":"2010-06-01T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/www.chbe.gatech.edu\/News\/PrausnitzAbstract.pdf","title":"Prausnitz\u0027s Abstract"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"135","name":"Research"}],"keywords":[{"id":"1612","name":"BME"},{"id":"1303","name":"chbe"},{"id":"109","name":"Georgia Tech"},{"id":"248","name":"IBB"},{"id":"495","name":"Mark Prausnitz"},{"id":"9699","name":"University of Oxford"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EJosie Giles\u003C\/strong\u003E\u003Cbr \/\u003ESchool of Chemical \u0026amp; Biomolecular Engineering\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=jg234\u0022\u003EContact Josie Giles\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-2299\u003C\/strong\u003E","format":"limited_html"}],"email":["josie.giles@chbe.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"54819":{"#nid":"54819","#data":{"type":"event","title":"First International Conference on Microneedles","body":[{"value":"\u003Cp\u003EThe first international symposium solely dedicated to microneedle research covering topics including microneedle fabrication, formulation, applications, and pre-clinical and clinical exemplification of microneedle technologies. The meeting will provide a stimulating forum for research exchange, discussion and networking through presentation of leading research by Keynote and Invited Speakers, an Industry Session focusing on commercially focused microneedle technologies and a short course on techniques for microneedle fabrication, formulation and biological assessment. \n\u003C\/p\u003E\n\u003Cp\u003ENetworking opportunities include dedicated time for poster presentations and a conference banquet. The conference fee structure hopes to encourage both established and young scientists to attend this exciting event, which is to be held in a new campus conference facility in the heart of Atlanta. \n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003ECall for abstracts through March 10, 2010\u003C\/strong\u003E\n\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"The first international symposium solely dedicated to microneedle research covering topics including microneedle fabrication, formulation, applications, and pre-clinical and clinical exemplification of microneedle technologies.","format":"limited_html"}],"field_summary_sentence":[{"value":"Call for abstracts through March 10, 2010"}],"uid":"27195","created_gmt":"2010-03-09 12:19:44","changed_gmt":"2016-10-08 01:48:59","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2010-05-24T01:00:00-04:00","event_time_end":"2010-05-26T13:00:00-04:00","event_time_end_last":"2010-05-26T13:00:00-04:00","gmt_time_start":"2010-05-24 05:00:00","gmt_time_end":"2010-05-26 17:00:00","gmt_time_end_last":"2010-05-26 17:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/microneedles.gatech.edu\/","title":"Microneedles Conference"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"109","name":"Georgia Tech"},{"id":"248","name":"IBB"},{"id":"495","name":"Mark Prausnitz"},{"id":"8520","name":"Microneedles Conference"},{"id":"497","name":"Parker H. Petit Institute for Bioengineering and Bioscience"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1789","name":"Conference\/Symposium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EMegan McDevitt\u003C\/strong\u003E\u003Cbr \/\u003EIBB\u003Cbr \/\u003E\u003Ca href=\u0022mailto:mcdevitt@ibb.gatech.edu\u0022\u003EContact Megan McDevitt\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-7001\u003C\/strong\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"56404":{"#nid":"56404","#data":{"type":"news","title":"Microneedles Research from Prausnitz Lab Featured in TIME.com","body":[{"value":"\u003Cp\u003EWhat if, instead of having to brave a hypodermic needle each time you needed a shot, you could simply slap on a patch and go about your day? According to some preliminary research from scientists at the Georgia Institute of Technology and Emory University, that possibility may be just a few years off.  The group of scientists, led by Mark Prausnitz, a professor of chemical and biomolecular engineering at Georgia Tech, have developed a patch that has five rows of tiny \u0022microneedles\u0022 about as wide as human hairs that can be used to painlessly administer vaccines and other medications. To test the efficiency of the new device, Prausnitz and his colleagues gave the flu vaccine to a group of mice, half by way of traditional injection, and half using the new microneedle patch. Later, the mice were exposed to the live flu virus, after which the scientists tested their immune responses and levels of antibodies. They found that the vaccine, administered via the patch, yielded the exact same level of protection as a traditional shot.\n\u003C\/p\u003E\n\u003Cp\u003E\u003Ca href=\u0027http:\/\/wellness.blogs.time.com\/2009\/08\/19\/a-patch-to-take-the-ouch-out-of-shots\/\u0027\u003EView full article\u003C\/a\u003E\n\u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0027http:\/\/www.chbe.gatech.edu\/drugdelivery\/\u0027\u003EVisit Prausnitz lab\u003C\/a\u003E\n\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"What if, instead of having to brave a hypodermic needle each time you needed a shot, you could simply slap on a patch and go about your day? According to some preliminary research from scientists at the Georgia Institute of Technology and Emory University, that possibility may be just a few years off.","format":"limited_html"}],"field_summary_sentence":[{"value":"A patch to take the ouch out of shots"}],"uid":"27195","created_gmt":"2009-08-20 00:00:00","changed_gmt":"2016-10-08 03:06:06","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2009-08-19T00:00:00-04:00","iso_date":"2009-08-19T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"56405":{"id":"56405","type":"image","title":"by Gary Meek","body":null,"created":"1449175629","gmt_created":"2015-12-03 20:47:09","changed":"1475894499","gmt_changed":"2016-10-08 02:41:39","alt":"by Gary Meek","file":{"fid":"190464","name":"tpw48481.jpg","image_path":"\/sites\/default\/files\/images\/tpw48481_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tpw48481_0.jpg","mime":"image\/jpeg","size":38849,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tpw48481_0.jpg?itok=w81VKUcP"}}},"media_ids":["56405"],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"135","name":"Research"}],"keywords":[{"id":"3346","name":"drug delivery"},{"id":"2780","name":"drug design"},{"id":"5910","name":"Drug Discovery"},{"id":"109","name":"Georgia Tech"},{"id":"248","name":"IBB"},{"id":"495","name":"Mark Prausnitz"},{"id":"7496","name":"microneedles"},{"id":"7537","name":"patch"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EColly Mitchell\u003C\/strong\u003E\u003Cbr \/\u003EParker H. Petit Institute for Bioengineering and Bioscience\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=cmitchell6\u0022\u003EContact Colly Mitchell\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-5982\u003C\/strong\u003E","format":"limited_html"}],"email":["colly.mitchell@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"56447":{"#nid":"56447","#data":{"type":"news","title":"Prausnitz Team\\\u0027s Microneedle Research Featured on CNN","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EMicroneedles May Be More Effective than Traditional Shots\u003C\/strong\u003E\u003Cbr \/\u003E\nCNN\n\u003C\/p\u003E\n\u003Cp\u003EIt\u0027s enough to make a kid scream.  A shot can be an unpleasant experience for anyone, no matter the age.  Funding by government flu grants, researchers at Georgia Tech and Emory University in Atlanta developed a solution - needles so small, you can\u0027t feel them.  It\u0027s as long as one or a few hairs are thick, said Georgia Tech researcher, Mark Prausnitz.  They\u0027re called microneedles, so tiny they only go part of the way through the skin, just deep enough to work but not enough to hit nerves and actually hurt.  Research shows microneedles might be more effective than traditional shots, and perhaps the biggest advantage, they\u0027re so simple, people can vaccinate themselves. If all goes well, researchers say in five years, microneedles could make doctors\u0027 visits a little more pain-free.  Brooke Baldwin, CNN, Atlanta.  To view the segment, go to following link to open file: \u003Ca href=\u0027http:\/\/web11.mediavsn.com\/UserSavedClips\/6ab9cff0-ed16-4f17-8870-cb66dff64927.asx\u0027\u003ECNN Video\u003C\/a\u003E\n\u003C\/p\u003E\n\u003Cp\u003ETo view Georgia Tech article:  \u003Ca href=\u0027http:\/\/www.gatech.edu\/newsroom\/release.html?id=2863\u0027\u003EFlu Vaccine Given In Microneedle Patches\u003C\/a\u003E\n\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Prausnitz Team\u0027s Microneedle Research Featured on CNN","format":"limited_html"}],"field_summary_sentence":[{"value":"Prausnitz Team\u0027s Microneedle Research Featured on CNN"}],"uid":"27195","created_gmt":"2009-06-01 00:00:00","changed_gmt":"2016-10-08 03:06:11","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2009-05-30T00:00:00-04:00","iso_date":"2009-05-30T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"146","name":"Life Sciences and Biology"},{"id":"135","name":"Research"}],"keywords":[{"id":"496","name":"CNN"},{"id":"498","name":"Flu Vaccine"},{"id":"109","name":"Georgia Tech"},{"id":"248","name":"IBB"},{"id":"495","name":"Mark Prausnitz"},{"id":"494","name":"Microneedle"},{"id":"497","name":"Parker H. Petit Institute for Bioengineering and Bioscience"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EColly Mitchell\u003C\/strong\u003E\u003Cbr \/\u003EParker H. Petit Institute for Bioengineering and Bioscience\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=cmitchell6\u0022\u003EContact Colly Mitchell\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-5982\u003C\/strong\u003E","format":"limited_html"}],"email":["colly.mitchell@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"46338":{"#nid":"46338","#data":{"type":"news","title":"Flu Vaccine Given in Microneedle Patches Proves Effective in Mice","body":[{"value":"\u003Cp\u003EFlu vaccine delivered through skin patches containing microneedles has proven just as effective at preventing influenza in mice as intramuscular, hypodermic flu immunization. A team of researchers at Emory University and the Georgia Institute of Technology believes the new microneedle skin patch method of delivering flu vaccine could improve overall seasonal vaccination coverage in people because of decreased pain, increased convenience, lower cost and simpler logistics over conventional hypodermic immunization.\n\u003C\/p\u003E\n\u003Cp\u003EThe research was published in the early online edition of the journal \u003Cem\u003EProceedings of the National Academy of Sciences \u003C\/em\u003E(PNAS). Another study by the research team on a different influenza strain was described in the journal \u003Cem\u003EPublic Library of Science \u003C\/em\u003E(PLoS) One. \n\u003C\/p\u003E\n\u003Cp\u003EThe patches used in the experiments contained an array of stainless steel microneedles coated with inactivated influenza virus. The patches were pressed manually into the skin and after a few minutes, the vaccine coating dissolved off within the skin. The coated microneedle immunizations were compared to conventional intramuscular hypodermic injections at the same dose in another group of mice. \n\u003C\/p\u003E\n\u003Cp\u003EThe researchers found that the microneedle vaccinations induced strong immune responses against influenza virus that were comparable to immune responses induced by the intramuscular, hypodermic immunizations. One month after vaccination, the researchers infected both groups of mice with a high dose of influenza virus. While all mice in a control group of unvaccinated mice died of influenza, all mice in both the hypodermic and the microneedle groups survived. \n\u003C\/p\u003E\n\u003Cp\u003E\u0022Our findings show that microneedle patches are just as effective at protecting against influenza as conventional hypodermic immunizations,\u0022 says Richard Compans, PhD, Emory professor of microbiology and immunology and one of the paper\u0027s senior authors. \u0022In addition, vaccine delivery into the skin is desirable because of the skin\u0027s rich immune network.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EEven though cutaneous immunization has been shown to induce a broad range of immune responses, and to be especially effective in individuals over age 60, this method has not been widely used because it has not been convenient and has required highly trained personnel.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022Unlike conventional hypodermic injections, microneedles are prepared in a patch for simple administration, possibly by patients themselves, and inserted painlessly onto the skin without specialized training,\u0022 says Mark Prausnitz, PhD, professor in the Georgia Tech School of Chemical and Biomolecular Engineering and co-senior author. \u0022These micron-scale needles can be mass produced using low-cost methods for distribution to doctors\u0027 offices, pharmacies and, possibly, people\u0027s homes.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EOther advantages of the microneedle patches could include more convenient storage, easier transportation and lower dosage requirements. Lower doses could be particularly important because flu vaccine production capacity sometimes is limited for seasonal vaccine, and a future influenza pandemic would require much greater production of vaccine. \n\u003C\/p\u003E\n\u003Cp\u003EReplacing a hypodermic needle with a microneedle patch also could significantly impact the way other vaccines are delivered, and could be particularly beneficial in developing countries. A microneedle patch could fit inside an envelope for delivery by the postal service and would occupy much less storage space. Patches also would increase vaccine safety by reducing the dangers of accidental or intentional hypodermic needle re-use. \n\u003C\/p\u003E\n\u003Cp\u003EThe project team plans future immunization studies in other animal models, including guinea pigs or ferrets, before initiating studies in humans. Also, more studies are needed to determine the minimum vaccine dose needed for full protection. \n\u003C\/p\u003E\n\u003Cp\u003EThe Emory and Georgia Tech research team began developing the new microneedle vaccine patch technology in 2007 using grants from the National Institutes of Health (NIH). The project team has extensive experience in microneedle development, influenza vaccines, vaccine delivery systems, product development and interdisciplinary collaboration.\n\u003C\/p\u003E\n\u003Cp\u003EIn 2007 the NIH awarded a $32.8 million, seven-year contract to Emory, along with the University of Georgia, to establish the Emory\/UGA Influenza Pathogenesis and Immunology Research Center. The center is working to improve the effectiveness of flu vaccines through a number of different projects studying how influenza viruses attack their hosts, how they are transmitted, and what new immune targets might be identified for antiviral medicines.\n\u003C\/p\u003E\n\u003Cp\u003EPrausnitz and his colleagues have been working since the mid 1990s to develop microneedle technology for painless drug and vaccine delivery through the skin. The Georgia Tech team has also developed manufacturing processes for microneedle patches and tested the ability of the needles to deliver proteins, vaccines, nanoparticles, and other small and large molecules through the skin.\n\u003C\/p\u003E\n\u003Cp\u003EOther authors of the papers are Emory microbiologists Ioanna Skountzou and Chinglai Yang, and first authors Ling Ye, Qiyun Zhu, Dimitrios Koutsonanos, and Maria del Pilar Martin from Emory and Vladimir Zarnitsyn from Georgia Tech. Other authors and contributors were Yulong Gao, Lei Pan, and Zhiyuan Wen from Emory, and Harvinder Gill and Sean Sullivan from Georgia Tech.\n\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"New Delivery Method Could Result in Simpler, Safer, Painless Vaccines"}],"field_summary":[{"value":"Flu vaccine delivered through skin patches containing microneedles has proven just as effective at preventing influenza in mice as intramuscular, hypodermic flu immunization.","format":"limited_html"}],"field_summary_sentence":[{"value":"Testing shows microneedle patches are effective for immunization"}],"uid":"27303","created_gmt":"2009-04-28 00:00:00","changed_gmt":"2016-10-08 03:03:14","author":"John Toon","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2009-04-28T00:00:00-04:00","iso_date":"2009-04-28T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"46339":{"id":"46339","type":"image","title":"Research team","body":null,"created":"1449174401","gmt_created":"2015-12-03 20:26:41","changed":"1475894416","gmt_changed":"2016-10-08 02:40:16","alt":"Research team","file":{"fid":"101108","name":"ttf55060.jpg","image_path":"\/sites\/default\/files\/images\/ttf55060_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/ttf55060_0.jpg","mime":"image\/jpeg","size":1505734,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/ttf55060_0.jpg?itok=2pAK5-_4"}},"46340":{"id":"46340","type":"image","title":"Microscope image","body":null,"created":"1449174401","gmt_created":"2015-12-03 20:26:41","changed":"1475894416","gmt_changed":"2016-10-08 02:40:16","alt":"Microscope image","file":{"fid":"101109","name":"tdz55060.jpg","image_path":"\/sites\/default\/files\/images\/tdz55060_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tdz55060_0.jpg","mime":"image\/jpeg","size":304370,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tdz55060_0.jpg?itok=HM98liVO"}},"46341":{"id":"46341","type":"image","title":"Stainless steel microneedles","body":null,"created":"1449174401","gmt_created":"2015-12-03 20:26:41","changed":"1475894416","gmt_changed":"2016-10-08 02:40:16","alt":"Stainless steel microneedles","file":{"fid":"101110","name":"tgi55060.jpg","image_path":"\/sites\/default\/files\/images\/tgi55060_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tgi55060_0.jpg","mime":"image\/jpeg","size":784064,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tgi55060_0.jpg?itok=oa9E0otX"}}},"media_ids":["46339","46340","46341"],"related_links":[{"url":"http:\/\/www.che.gatech.edu\/","title":"School of Chemical and Biomolecular Engineering"},{"url":"http:\/\/www.chbe.gatech.edu\/fac_staff\/faculty\/prausnitz.php","title":"Mark Prausnitz"},{"url":"http:\/\/www.emory.edu\/","title":"Emory University"}],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"135","name":"Research"}],"keywords":[{"id":"764","name":"immunization"},{"id":"765","name":"influenza"},{"id":"494","name":"Microneedle"},{"id":"170850","name":"skin"},{"id":"763","name":"vaccine"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EJohn Toon\u003C\/strong\u003E\u003Cbr \/\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=jt7\u0022\u003EContact John Toon\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-6986\u003C\/strong\u003E","format":"limited_html"}],"email":["jtoon@gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"56264":{"#nid":"56264","#data":{"type":"news","title":"ChBE Professor Mark Prausnitz Elected to the AIMBE College of Fellows","body":[{"value":"\u003Cp\u003EMark Prausnitz, Professor \u0026amp; the Emerson Lewis Faculty Fellow in Chemical \u0026amp; Biomolecular Engineering, was elected as one of the newest members of the College of Fellows by The American Institute for Medical and Biological Engineering (AIMBE). The newly elected Fellows were nominated and approved by current Fellows of the College, consisting of more than 900 engineers and scientists.\u003C\/p\u003E\n\u003Cp\u003ERecipients of this honor are recognized for their outstanding achievements in medical and biological engineering. A formal induction ceremony will be held during the Institute\u0027s Annual Event at the National Academy of Sciences building in Washington, D.C. on February 11-13, 2009.\u003C\/p\u003E\n\u003Cp\u003EABOUT DR. MARK PRAUSNITZ\u003Cbr \/\u003E\nDr. Prausnitz and his colleagues carry out research on biophysical methods of drug delivery using ultrasound, microneedles and other approaches. The success of drug and gene delivery is limited by the inability of drugs, proteins and DNA to cross biological barriers in the body. The most daunting barrier is that posed by lipid bilayers, which block transport into cells, into tissues, and into the body. The Prausnitz lab studies the effect of ultrasound and microneedles to selectively and reversibly disrupt those biological barriers and thereby deliver drugs into the body across the skin, into the eye, and into targeted cells through short-lived holes their membranes. Ultrasound studies focus on the mechanisms by which ultrasound disrupts membranes and drives intracellular delivery of molecules, as well as mechanisms of cell death. Microneedles studies address basic questions of drug transport, avoidance of pain, and insertion mechanics of microneedles in skin along with applied questions relating to drug and vaccine delivery and needle fabrication technologies. Additional studies address electroporation for drug and gene delivery, pore-forming peptides for transdermal delivery, theoretical and experimental studies of drug delivery to the eye, and enhanced transfection of plant cells for forestry biotechnology.\n\u003C\/p\u003E\n\u003Cp\u003EIn addition to training graduate students in the laboratory, Dr. Prausnitz is actively involved with teaching undergraduate students in the classroom. His core courses are introductory classes on mass and energy balances and thermodynamics and the upper-division course on unit operations laboratory. An elective course developed by Dr. Prausnitz is entitled \u0022Effective Communication for Professional Engineering,\u0022 which addresses oral and written communication in the context of a case study of the nicotine patch.\n\u003C\/p\u003E\n\u003Cp\u003EAnother elective course, developed in collaboration with Dr. Bommarius, is entitled \u0022Drug Design, Development, and Delivery.\u0022 This course for senior undergraduates and graduate students exposes students to the interplay between multiple technical, as well as economic and societal factors that influence the creation of a successful pharmaceutical.\n\u003C\/p\u003E\n\u003Cp\u003EDr. Prausnitz has co-authored more than 100 research articles, given 120 invited lectures to industry and academia, published 170 conference abstracts, holds close to 20 issued or pending patents, and has served as an expert witness. Among his honors are the NSF\/NIH Scholar-in-Residence at the National Institutes of Health, CAREER Young Investigator Award from the National Science Foundation, TR100 Young Innovator Award from Technology Review and Young Investigator Award and Outstanding Pharmaceutical Paper Award from the Controlled Release Society.\u003C\/p\u003E\n\u003Cp\u003EABOUT AIMBE AND THE COLLEGE OF FELLOWS\u003Cbr \/\u003E\nThe College of Fellows leads the way in technological advancement, advocating for\u003Cbr \/\u003E\npublic policies facilitating progress in medical and biological research and development\u003Cbr \/\u003E\nto benefit the public. Since 1991, AIMBE Fellows have helped to revolutionize medicine, engineering and related fields that enhance and extend the lives of people all over the\u003Cbr \/\u003E\nworld. Counting several Nobel Prize winners among them, through their work the Fellows also help protect the environment, lead to new national security safeguards, and contribute to a better, healthier society in many other ways.\n\u003C\/p\u003E\n\u003Cp\u003EWith Fellows in every U.S. state\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Mark Prausnitz, Professor \u0026amp; the Emerson Lewis Faculty Fellow in Chemical \u0026amp; Biomolecular Engineering, was elected as one of the newest members of the College of Fellows by The American Institute for Medical and Biological Engineering (AIMBE). The newly elected Fellows were nominated and approved by current Fellows of the College, consisting of more than 900 engineers and scientists.","format":"limited_html"}],"field_summary_sentence":[{"value":"ChBE Professor Mark Prausnitz Elected to the AIMBE College of Fe"}],"uid":"27255","created_gmt":"2008-11-06 01:00:00","changed_gmt":"2016-10-08 03:06:01","author":"Josie Giles","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2008-11-06T00:00:00-05:00","iso_date":"2008-11-06T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"56265":{"id":"56265","type":"image","title":"Dr. Mark Prausnitz","body":null,"created":"1449175629","gmt_created":"2015-12-03 20:47:09","changed":"1475894499","gmt_changed":"2016-10-08 02:41:39","alt":"Dr. Mark Prausnitz","file":{"fid":"190428","name":"tcr92033.jpg","image_path":"\/sites\/default\/files\/images\/tcr92033_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tcr92033_0.jpg","mime":"image\/jpeg","size":111433,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tcr92033_0.jpg?itok=Dls0geIY"}}},"media_ids":["56265"],"related_links":[{"url":"http:\/\/www.che.gatech.edu\/drugdelivery\/","title":"Dr. Prausnitz\\\u0027s Research Group"},{"url":"http:\/\/www.aimbe.org\/index.php","title":"The American Institute for Medical and Biological Engineering"}],"groups":[{"id":"1240","name":"School of Chemical and Biomolecular Engineering"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"135","name":"Research"}],"keywords":[{"id":"1007","name":"AIMBE"},{"id":"276","name":"Awards"},{"id":"2548","name":"biomedical"},{"id":"1303","name":"chbe"},{"id":"1704","name":"chemical \u0026 biomolecular engineering"},{"id":"560","name":"chemical engineering"},{"id":"495","name":"Mark Prausnitz"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EJosie Giles\u003C\/strong\u003E\u003Cbr \/\u003ESchool of Chemical \u0026amp; Biomolecular Engineering\u003Cbr \/\u003E\u003Ca href=\u0022mailto:josie@gatech.edu\u0022\u003EContact Josie Giles\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-2299\u003C\/strong\u003E","format":"limited_html"}],"email":["josie@gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"56322":{"#nid":"56322","#data":{"type":"news","title":"New Patch Could Eliminate Needles","body":[{"value":"\u003Cp\u003EVaccines can help keep you healthy, but suffering through the protective shot can be downright painful. Now, researchers may have come up with a new way of soothing the sting.\u003C\/p\u003E\n\u003Cp\u003EKelly Marie Boyd doesn\u0027t do well when waiting to get a shot. \n\u003C\/p\u003E\n\u003Cp\u003E\u0022I will start feeling faint, feeling nauseated before they even walk into the room. If I see a needle, I will pass out,\u0022 she said. With a little girl on the way, she dreads having to put her baby through childhood vaccinations.\n\u003C\/p\u003E\n\u003Cp\u003EA new invention may help make things less terrifying for Kelly and others like her. The new tool could eliminate a need for needles, by using what\u0027s called a transdermal patch.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022That way you can put the drug on the skin. It sits there for a period of time and the drug makes its way across the skin,\u0022 said Dr. Mark Prausnitz of Georgia Institute of Technology.\n\u003C\/p\u003E\n\u003Cp\u003EThe \u0022microneedles\u0022 work just like a nicotine patch, but use - you guessed it - microscopic needles. \u0022So small that on the one hand, you don\u0027t feel them. Probably you don\u0027t even see them,\u0022 Prausnitz said.\n\u003C\/p\u003E\n\u003Cp\u003EOn the other hand, they\u0027re large enough to do what\u0027s needed. \u0022The channels that they have are big enough to deliver most any drug or even vaccine that you would like to give,\u0022 Prausnitz said.\n\u003C\/p\u003E\n\u003Cp\u003ENot only is it less painful, this may also be a more effective way of delivering drugs. \n\u003C\/p\u003E\n\u003Cp\u003E\u0022There is a class of immune cells that live in the very top layer of skin. So, if you can give the vaccine right there at the top layer of skin, you can get a better immune response,\u0022 Prausnitz said.\n\u003C\/p\u003E\n\u003Cp\u003EWith a better response, smaller doses of the drug may be given than what is traditionally needed. You may even be able to use them right at home. \n\u003C\/p\u003E\n\u003Cp\u003E\u0022You just stick it on and you\u0027re done,\u0022 Dr. Prausnitz said. \n\u003C\/p\u003E\n\u003Cp\u003EResearchers hope these microneedles will have a big impact in third-world countries, where there\u0027s a huge need for a better way to vaccinate large groups against deadly diseases such as hepatitis B and smallpox.\n\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"ChBE professor Mark Prausnitz and his research team have developed a new, less painful method for administering vaccines.","format":"limited_html"}],"field_summary_sentence":[{"value":"Vaccines can help keep you healthy, but suffering t"}],"uid":"27255","created_gmt":"2006-07-14 00:00:00","changed_gmt":"2016-10-08 03:06:01","author":"Josie Giles","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2005-06-09T00:00:00-04:00","iso_date":"2005-06-09T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"56323":{"id":"56323","type":"image","title":"Traditional Drug Delivery","body":null,"created":"1449175629","gmt_created":"2015-12-03 20:47:09","changed":"1475894499","gmt_changed":"2016-10-08 02:41:39","alt":"Traditional Drug Delivery","file":{"fid":"190450","name":"tjs97045.jpg","image_path":"\/sites\/default\/files\/images\/tjs97045_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tjs97045_0.jpg","mime":"image\/jpeg","size":11482,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tjs97045_0.jpg?itok=jj3rzrQw"}}},"media_ids":["56323"],"related_links":[{"url":"http:\/\/cbs2chicago.com\/health\/local_story_160160916.html","title":"CBS2 Chicago Web Site (Original Story)"}],"groups":[{"id":"1240","name":"School of Chemical and Biomolecular Engineering"}],"categories":[{"id":"135","name":"Research"}],"keywords":[{"id":"1303","name":"chbe"},{"id":"560","name":"chemical engineering"},{"id":"495","name":"Mark Prausnitz"},{"id":"365","name":"Research"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EJosie Giles\u003C\/strong\u003E\u003Cbr \/\u003ESchool of Chemical \u0026amp; Biomolecular Engineering\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=jg234\u0022\u003EContact Josie Giles\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-2299\u003C\/strong\u003E","format":"limited_html"}],"email":["josie.giles@chbe.gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}