{"622813":{"#nid":"622813","#data":{"type":"event","title":"Immunoengineering Seminar Series","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EEncoding and Decoding Specificity in Adaptive Immunity by Deep Learning\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ESai Reddy, Ph.D.\u003Cbr \/\u003E\r\nAssociate Professor\u003Cbr \/\u003E\r\nDepartment of Biosystems Science and Engineering\u0026nbsp;\u003Cbr \/\u003E\r\nETH Zurich\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EThe ability to predict and correspondingly manipulate adaptive immune responses is highly valuable for biotechnology and medicine. To achieve this requires a greater molecular understanding of antigen selection and specificity by adaptive immune cells. In this I will explain how we are using deep learning to identify patterns of antigen-specificity in antibody responses following immunization. Deep neural networks are used to elucidate the antibody sequence space by generating thousands of novel and functional variants \u003Cem\u003Ein-silico\u003C\/em\u003E, highlighting how deep learning can be used to encode and decode specificity in adaptive immunity.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"\u0022Encoding and Decoding Specificity in Adaptive Immunity by Deep Learning\u0022 - Sai Reddy, Ph.D. - ETH Zurich"}],"uid":"27349","created_gmt":"2019-06-27 14:35:45","changed_gmt":"2019-06-27 14:35:45","author":"Floyd Wood","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2019-08-26T12:00:00-04:00","event_time_end":"2019-08-26T13:00:00-04:00","event_time_end_last":"2019-08-26T13:00:00-04:00","gmt_time_start":"2019-08-26 16:00:00","gmt_time_end":"2019-08-26 17:00:00","gmt_time_end_last":"2019-08-26 17:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/immunoengineering.gatech.edu\/","title":"Center for Immunoengineering"},{"url":"https:\/\/bsse.ethz.ch\/lsi\/the-lab\/People\/STR.html","title":"Reddy profile"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"126571","name":"go-PetitInstitute"},{"id":"248","name":"IBB"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"177814","name":"Postdoc"},{"id":"174045","name":"Graduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:susan.thomas@me.gatech.edu\u0022\u003ESusan Thomas\u003C\/a\u003E, faculty host\u003C\/p\u003E\r\n","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}