{"640571":{"#nid":"640571","#data":{"type":"event","title":"Digging Ancient Haplotypes out of Modern Human Genomes","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003ELuca Pagani, Ph.D.\u003Cbr \/\u003E\r\nDepartment of Biology\u003Cbr \/\u003E\r\nUniversity of Padova\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Ca href=\u0022https:\/\/bluejeans.com\/688157141\u0022\u003EView S\u003C\/a\u003E\u003Ca href=\u0022https:\/\/youtu.be\/_n8CLtPDV8c\u0022\u003Eeminar\u003C\/a\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EABSTRACT\u003Cbr \/\u003E\r\nA growing body of human ancient DNA evidence is being used to build increasingly more realistic models of demographic changes in the last few thousand years. However, due to low coverage and low sample size, in most cases ancient DNA is inherently limited in providing phased haplotypes and accurate population-level allele frequency estimates.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EHere we propose to consider modern genomes as being arranged together from pieces of a jigsaw of ancient haplotypes that recombined and admixed in the last few thousand years. Following what has already been attempted for recently admixed populations, one can use local ancestry methods to extract these genomic regions and study them separately. The benefit of this approach stems from our ability to make use of existing high-quality whole genomes, which can be deconvoluted to identify the genetic makeup of the ancient populations that admixed to form contemporary human groups.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EHost: \u003Ca href=\u0022https:\/\/biosciences.gatech.edu\/people\/joseph-lachance\u0022\u003EJoe Lachance, Ph.D.\u003C\/a\u003E\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Biological Sciences Seminar by Luca Pagani, Ph.D."}],"uid":"27964","created_gmt":"2020-10-26 12:43:02","changed_gmt":"2021-04-08 22:23:00","author":"Jasmine Martin","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2020-11-12T11:00:00-05:00","event_time_end":"2020-11-13T11:59:00-05:00","event_time_end_last":"2020-11-13T11:59:00-05:00","gmt_time_start":"2020-11-12 16:00:00","gmt_time_end":"2020-11-13 16:59:00","gmt_time_end_last":"2020-11-13 16:59:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"hg_media":{"640568":{"id":"640568","type":"image","title":"Luca Pagani, Ph.D.","body":null,"created":"1603715480","gmt_created":"2020-10-26 12:31:20","changed":"1603715480","gmt_changed":"2020-10-26 12:31:20","alt":"","file":{"fid":"243478","name":"Luca Pagani.jpg","image_path":"\/sites\/default\/files\/images\/Luca%20Pagani.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/Luca%20Pagani.jpg","mime":"image\/jpeg","size":390057,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/Luca%20Pagani.jpg?itok=TsWT2Jhm"}}},"media_ids":["640568"],"groups":[{"id":"1275","name":"School of Biological Sciences"}],"categories":[],"keywords":[{"id":"166882","name":"School of Biological Sciences"},{"id":"170037","name":"Joe Lachance"},{"id":"186089","name":"Luca Pagani"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"177814","name":"Postdoc"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EFor additional login information contact \u003Ca href=\u0022mailto:jasmine.martin@biosci.gatech.edu?subject=Additional%20Login%20Details%20for%20Seminar\u0022\u003EJasmine Martin\u003C\/a\u003E\u003C\/p\u003E\r\n","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}