{"64197":{"#nid":"64197","#data":{"type":"event","title":"Functional Molecular Imaging in the Brain","body":[{"value":"\u003Cp\u003EAbstract:\u003Cbr \/\u003E\nFunctional magnetic resonance imaging (fMRI) with contrast agents\nsensitive to neural activity could have great impact in neuroscience by\ncombining noninvasive whole-brain coverage with molecular-level\nspecificity for neuronal events. My laboratory is developing molecular\nfMRI approaches based on molecular sensors we have designed to detect\nintra- and extracellular signalling events in the nervous system.\u0026nbsp; Our\nsensors are built on a variety of chemical platforms, ranging from\nsmall molecules to nanoparticles.\u0026nbsp; Protein-based contrast agents are of\nparticular interest to us because of the possibility of gene-based\nbrain delivery strategies and the availability of powerful protein\nengineering techniques.\u0026nbsp; Here we describe molecular engineering of\nseveral MRI sensors for neural activity, as well as the first efforts\nin our laboratory to perform functional neuroimaging with molecular\nspecificity in living brains.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EBioengineering Seminar Series\u003C\/p\u003E\u003Cp\u003EAlan Jasanoff, PhD\u0026nbsp; - Massachusetts Institute of Technology\u0026nbsp;\n\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003EFunctional Molecular Imaging in the Brain\u003C\/em\u003E\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Alan Jasanoff, PhD - Massachusetts Institute of Technology"}],"uid":"27195","created_gmt":"2011-02-11 11:00:11","changed_gmt":"2016-10-08 01:54:05","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-02-24T10:00:00-05:00","event_time_end":"2011-02-24T11:00:00-05:00","event_time_end_last":"2011-02-24T11:00:00-05:00","gmt_time_start":"2011-02-24 15:00:00","gmt_time_end":"2011-02-24 16:00:00","gmt_time_end_last":"2011-02-24 16:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/web.mit.edu\/jasanofflab\/","title":"Jasanoff Lab"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"11877","name":"BioE Seminar"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EFaculty Host: Xiaoping Hu (404) 712-2730\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}