{"652050":{"#nid":"652050","#data":{"type":"event","title":"Oral Microbiome Geography: The Site-Specialist Hypothesis ","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EGary Borisy, Ph.D.\u003Cbr \/\u003E\r\nSenior Investigator\u003Cbr \/\u003E\r\nForsyth Institute\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Ca href=\u0022https:\/\/bluejeans.com\/228677182\/4554\u0022\u003EBlueJeans Seminar\u003C\/a\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EABSTRACT\u003C\/strong\u003E\u003Cbr \/\u003E\r\nThe concept that different sites within the mouth support distinctive microbiotas was introduced almost 50 years ago. Subsequently, high-throughput profiling of microbes using culture-independent, DNA sequence methods showed that sites within the mouth could be distinguished by the composition of their resident microbiota. We suggest a stronger conclusion is warranted which we term the site-specialist hypothesis: that each microbe in the mouth is specialized for one habitat or a cluster of related habitats, so that the microbiota at one oral site are different from the microbiota at other oral sites not only in overall composition and proportions of common taxa but also in specific membership.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003EWe evaluate the site-specialist hypothesis by a combination of imaging and genomics approaches. Our imaging approach employs multiplexed fluorescence in situ hybridization to localize individual taxa at the micron scale.\u0026nbsp;\u0026nbsp;Our genomics approach employs the construction of multispecies pangenomes and read recruitment from metagenomic samples collected from individual oral sites to evaluate the presence of individual strains at different sites within the mouth.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003EHost: Juan P Barraza, Ph.D. student, Whiteley Lab\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Biological Sciences Seminar by Gary Borisy, Ph.D."}],"uid":"27964","created_gmt":"2021-10-26 03:15:05","changed_gmt":"2021-11-01 11:49:21","author":"Jasmine Martin","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2021-11-04T13:00:00-04:00","event_time_end":"2021-11-04T14:00:00-04:00","event_time_end_last":"2021-11-04T14:00:00-04:00","gmt_time_start":"2021-11-04 17:00:00","gmt_time_end":"2021-11-04 18:00:00","gmt_time_end_last":"2021-11-04 18:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"hg_media":{"652051":{"id":"652051","type":"image","title":"Gary Borisy, Ph.D.","body":null,"created":"1635218260","gmt_created":"2021-10-26 03:17:40","changed":"1635218260","gmt_changed":"2021-10-26 03:17:40","alt":"","file":{"fid":"247389","name":"Gary Borisy2.jpg","image_path":"\/sites\/default\/files\/images\/Gary%20Borisy2.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/Gary%20Borisy2.jpg","mime":"image\/jpeg","size":691141,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/Gary%20Borisy2.jpg?itok=wgzT2D9c"}}},"media_ids":["652051"],"groups":[{"id":"1275","name":"School of Biological Sciences"}],"categories":[],"keywords":[{"id":"189167","name":"Gary Borisy"},{"id":"166882","name":"School of Biological Sciences"},{"id":"166892","name":"School of Biological Sciences Seminar"},{"id":"172458","name":"biological sciences"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"177814","name":"Postdoc"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}