{"60096":{"#nid":"60096","#data":{"type":"news","title":"Vaccine-Delivery Patch with Dissolving Microneedles Boosts Protection","body":[{"value":"\u003Cp\u003EA new vaccine-delivery patch based on hundreds of microscopic needles that dissolve into the skin could allow persons without medical training to painlessly administer vaccines -- while providing improved immunization against diseases such as influenza.\u003C\/p\u003E\u003Cp\u003EPatches containing micron-scale needles that carry vaccine with them as they dissolve into the skin could simplify immunization programs by eliminating the use of hypodermic needles -- and their \u0022sharps\u0022 disposal and re-use concerns. Applied easily to the skin, the microneedle patches could allow self-administration of vaccine during pandemics and simplify large-scale immunization programs in developing nations. \u003C\/p\u003E\u003Cp\u003EDetails of the dissolving microneedle patches and immunization benefits observed in experimental mice were reported July 18th in the advance online publication of the journal \u003Cem\u003ENature Medicine\u003C\/em\u003E. Conducted by researchers from Emory University and the Georgia Institute of Technology, the study is believed to be the first to evaluate the immunization benefits of dissolving microneedles. The research was supported by the National Institutes of Health (NIH). \u003C\/p\u003E\u003Cp\u003E\u0022In this study, we have shown that a dissolving microneedle patch can vaccinate against influenza at least as well, and probably better than, a traditional hypodermic needle,\u0022 said Mark Prausnitz, a professor in the Georgia Tech School of Chemical and Biomolecular Engineering. \u003C\/p\u003E\u003Cp\u003EJust 650 microns in length and assembled into an array of 100 needles for the mouse study, the dissolving microneedles penetrate the outer layers of skin. Beyond their other advantages, the dissolving microneedles appear to provide improved immunity to influenza when compared to vaccination with hypodermic needles. \u003C\/p\u003E\u003Cp\u003E\u0022The skin is a particularly attractive site for immunization because it contains an abundance of the types of cells that are important in generating immune responses to vaccines,\u0022 said Richard Compans, professor of microbiology and immunology at Emory University School of Medicine. \u003C\/p\u003E\u003Cp\u003EIn the study, one group of mice received the influenza vaccine using traditional hypodermic needles injecting into muscle; another group received the vaccine through dissolving microneedles applied to the skin, while a control group had microneedle patches containing no vaccine applied to their skin. When infected with influenza virus 30 days later, both groups that had received the vaccine remained healthy while mice in the control group contracted the disease and died. \u003C\/p\u003E\u003Cp\u003EThree months after vaccination, the researchers also exposed a different group of immunized mice to flu virus and found that animals vaccinated with microneedles appeared to have a better \u0022recall\u0022 response to the virus and thus were able to clear the virus from their lungs more effectively than those that received vaccine with hypodermic needles. \u003C\/p\u003E\u003Cp\u003E\u0022Another advantage of these microneedles is that the vaccine is present as a dry formulation, which will enhance its stability during distribution and storage,\u0022 said Ioanna Skountzou, an Emory University assistant professor. \u003C\/p\u003E\u003Cp\u003EPressed into the skin, the microneedles quickly dissolve in bodily fluids, leaving only the water-soluble backing. The backing can be discarded because it no longer contains any sharps. \u003C\/p\u003E\u003Cp\u003E\u0022We envision people getting the patch in the mail or at a pharmacy and then self administering it at home,\u0022 said Sean Sullivan, the study\u2019s lead author from Georgia Tech. \u0022Because the microneedles on the patch dissolve away into the skin, there would be no dangerous sharp needles left over.\u0022 \u003C\/p\u003E\u003Cp\u003EThe microneedle arrays were made from a polymer material, poly-vinyl pyrrolidone, that has been shown to be safe for use in the body. Freeze-dried vaccine was mixed with the vinyl-pyrrolidone monomer before being placed into microneedle molds and polymerized at room temperature using ultraviolet light. \u003C\/p\u003E\u003Cp\u003EIn many parts of the world, poor medical infrastructure leads to the re-use of hypodermic needles, contributing to the spread of diseases such as HIV and hepatitis B. Dissolving microneedle patches would eliminate re-use while allowing vaccination to be done by personnel with minimal training. \u003C\/p\u003E\u003Cp\u003EThough the study examined only the administration of flu vaccine with the dissolving microneedles, the technique should be useful for other immunizations. If mass-produced, the microneedle patches are expected to cost about the same as conventional needle-and-syringe techniques, and may lower the overall cost of immunization programs by reducing personnel costs and waste disposal requirements, Prausnitz said. \u003C\/p\u003E\u003Cp\u003EBefore dissolving microneedles can be made widely available, however, clinical studies will have to be done to assure safety and effectiveness. Other vaccine formulation techniques may also be studied, and researchers will want to better understand why vaccine delivery with dissolving microneedles has been shown to provide better protection. \u003C\/p\u003E\u003Cp\u003EBeyond those already mentioned, the study involved Jeong-Woo Lee, Vladimir Zarnitsyn, Seong-O Choi and Niren Murthy from Georgia Tech, and Dimitrios Koutsonanos and Maria del Pilar Martin from Emory University. \u003C\/p\u003E\u003Cp\u003E\u0022The dissolving microneedle patch could open up many new doors for immunization programs by eliminating the need for trained personnel to carry out the vaccination,\u0022 Prausnitz said. \u0022This approach could make a significant impact because it could enable self-administration as well as simplify vaccination programs in schools and assisted living facilities.\u0022 \u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003EGeorgia Institute of Technology\u003Cbr \/\u003E75 Fifth Street, N.W., Suite 314\u003Cbr \/\u003EAtlanta, Georgia 30308 USA\u003C\/strong\u003E \u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EMedia Relations Contacts\u003C\/strong\u003E: John Toon, Georgia Tech (404-894-6986) (\u003Ca href=\u0022mailto:jtoon@gatech.edu\u0022\u003Ejtoon@gatech.edu\u003C\/a\u003E), Holly Korschun, Emory University (404-727-3990) (\u003Ca href=\u0022mailto:hkorsch@emory.edu\u0022\u003Ehkorsch@emory.edu\u003C\/a\u003E) or Abby Vogel Robinson, Georgia Tech (404-385-3364) (\u003Ca href=\u0022mailto:abby@innovate.gatech.edu\u0022\u003Eabby@innovate.gatech.edu\u003C\/a\u003E). \u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EWriter\u003C\/strong\u003E: John Toon \u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"Device Replaces Hypodermic Needles to Eliminate Sharp Waste"}],"field_summary":[{"value":"\u003Cp\u003EA new vaccine-delivery patch based on hundreds of microscopic needles that dissolve into the skin could allow persons without medical training to painlessly administer vaccines \u2013 while providing improved immunization against diseases such as influenza.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Dissolving microneedles offer a new vaccine-delivery solution"}],"uid":"27303","created_gmt":"2010-07-18 00:00:00","changed_gmt":"2016-10-08 03:07:11","author":"John Toon","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2010-07-18T00:00:00-04:00","iso_date":"2010-07-18T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"60097":{"id":"60097","type":"image","title":"Dissolving microneedles on fingertip","body":null,"created":"1449176239","gmt_created":"2015-12-03 20:57:19","changed":"1475894520","gmt_changed":"2016-10-08 02:42:00","alt":"Dissolving microneedles on fingertip","file":{"fid":"191051","name":"tvn90868.jpg","image_path":"\/sites\/default\/files\/images\/tvn90868_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tvn90868_0.jpg","mime":"image\/jpeg","size":428627,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tvn90868_0.jpg?itok=XnfaXzLx"}},"60098":{"id":"60098","type":"image","title":"Dissolving microneedles on application.","body":null,"created":"1449176239","gmt_created":"2015-12-03 20:57:19","changed":"1475894520","gmt_changed":"2016-10-08 02:42:00","alt":"Dissolving microneedles on application.","file":{"fid":"191052","name":"tvw90868.jpg","image_path":"\/sites\/default\/files\/images\/tvw90868_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tvw90868_0.jpg","mime":"image\/jpeg","size":534894,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tvw90868_0.jpg?itok=0nHMgk9n"}},"60099":{"id":"60099","type":"image","title":"Dissolving microneedles after on minute.","body":null,"created":"1449176239","gmt_created":"2015-12-03 20:57:19","changed":"1475894520","gmt_changed":"2016-10-08 02:42:00","alt":"Dissolving microneedles after on minute.","file":{"fid":"191053","name":"tjx90868.jpg","image_path":"\/sites\/default\/files\/images\/tjx90868_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tjx90868_0.jpg","mime":"image\/jpeg","size":603655,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tjx90868_0.jpg?itok=LDwBMIKz"}}},"media_ids":["60097","60098","60099"],"related_links":[{"url":"http:\/\/www.chbe.gatech.edu\/fac_staff\/faculty\/prausnitz.php","title":"Mark Prausnitz"},{"url":"http:\/\/microbiology.emory.edu\/compans_r.html","title":"Richard Compans"},{"url":"http:\/\/www.chbe.gatech.edu\/","title":"School of Chemical \u0026 Biomolecular Engineering"},{"url":"http:\/\/www.med.emory.edu\/","title":"Emory University School of Medicine"}],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"145","name":"Engineering"},{"id":"147","name":"Military Technology"},{"id":"135","name":"Research"}],"keywords":[{"id":"296","name":"Flu"},{"id":"764","name":"immunization"},{"id":"765","name":"influenza"},{"id":"494","name":"Microneedle"},{"id":"170850","name":"skin"},{"id":"763","name":"vaccine"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EJohn Toon\u003C\/strong\u003E\u003Cbr \/\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=jt7\u0022\u003EContact John Toon\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-6986\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["jtoon@gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"56447":{"#nid":"56447","#data":{"type":"news","title":"Prausnitz Team\\\u0027s Microneedle Research Featured on CNN","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EMicroneedles May Be More Effective than Traditional Shots\u003C\/strong\u003E\u003Cbr \/\u003E\nCNN\n\u003C\/p\u003E\n\u003Cp\u003EIt\u0027s enough to make a kid scream.  A shot can be an unpleasant experience for anyone, no matter the age.  Funding by government flu grants, researchers at Georgia Tech and Emory University in Atlanta developed a solution - needles so small, you can\u0027t feel them.  It\u0027s as long as one or a few hairs are thick, said Georgia Tech researcher, Mark Prausnitz.  They\u0027re called microneedles, so tiny they only go part of the way through the skin, just deep enough to work but not enough to hit nerves and actually hurt.  Research shows microneedles might be more effective than traditional shots, and perhaps the biggest advantage, they\u0027re so simple, people can vaccinate themselves. If all goes well, researchers say in five years, microneedles could make doctors\u0027 visits a little more pain-free.  Brooke Baldwin, CNN, Atlanta.  To view the segment, go to following link to open file: \u003Ca href=\u0027http:\/\/web11.mediavsn.com\/UserSavedClips\/6ab9cff0-ed16-4f17-8870-cb66dff64927.asx\u0027\u003ECNN Video\u003C\/a\u003E\n\u003C\/p\u003E\n\u003Cp\u003ETo view Georgia Tech article:  \u003Ca href=\u0027http:\/\/www.gatech.edu\/newsroom\/release.html?id=2863\u0027\u003EFlu Vaccine Given In Microneedle Patches\u003C\/a\u003E\n\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Prausnitz Team\u0027s Microneedle Research Featured on CNN","format":"limited_html"}],"field_summary_sentence":[{"value":"Prausnitz Team\u0027s Microneedle Research Featured on CNN"}],"uid":"27195","created_gmt":"2009-06-01 00:00:00","changed_gmt":"2016-10-08 03:06:11","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2009-05-30T00:00:00-04:00","iso_date":"2009-05-30T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"146","name":"Life Sciences and Biology"},{"id":"135","name":"Research"}],"keywords":[{"id":"496","name":"CNN"},{"id":"498","name":"Flu Vaccine"},{"id":"109","name":"Georgia Tech"},{"id":"248","name":"IBB"},{"id":"495","name":"Mark Prausnitz"},{"id":"494","name":"Microneedle"},{"id":"497","name":"Parker H. Petit Institute for Bioengineering and Bioscience"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EColly Mitchell\u003C\/strong\u003E\u003Cbr \/\u003EParker H. Petit Institute for Bioengineering and Bioscience\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=cmitchell6\u0022\u003EContact Colly Mitchell\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-5982\u003C\/strong\u003E","format":"limited_html"}],"email":["colly.mitchell@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"46338":{"#nid":"46338","#data":{"type":"news","title":"Flu Vaccine Given in Microneedle Patches Proves Effective in Mice","body":[{"value":"\u003Cp\u003EFlu vaccine delivered through skin patches containing microneedles has proven just as effective at preventing influenza in mice as intramuscular, hypodermic flu immunization. A team of researchers at Emory University and the Georgia Institute of Technology believes the new microneedle skin patch method of delivering flu vaccine could improve overall seasonal vaccination coverage in people because of decreased pain, increased convenience, lower cost and simpler logistics over conventional hypodermic immunization.\n\u003C\/p\u003E\n\u003Cp\u003EThe research was published in the early online edition of the journal \u003Cem\u003EProceedings of the National Academy of Sciences \u003C\/em\u003E(PNAS). Another study by the research team on a different influenza strain was described in the journal \u003Cem\u003EPublic Library of Science \u003C\/em\u003E(PLoS) One. \n\u003C\/p\u003E\n\u003Cp\u003EThe patches used in the experiments contained an array of stainless steel microneedles coated with inactivated influenza virus. The patches were pressed manually into the skin and after a few minutes, the vaccine coating dissolved off within the skin. The coated microneedle immunizations were compared to conventional intramuscular hypodermic injections at the same dose in another group of mice. \n\u003C\/p\u003E\n\u003Cp\u003EThe researchers found that the microneedle vaccinations induced strong immune responses against influenza virus that were comparable to immune responses induced by the intramuscular, hypodermic immunizations. One month after vaccination, the researchers infected both groups of mice with a high dose of influenza virus. While all mice in a control group of unvaccinated mice died of influenza, all mice in both the hypodermic and the microneedle groups survived. \n\u003C\/p\u003E\n\u003Cp\u003E\u0022Our findings show that microneedle patches are just as effective at protecting against influenza as conventional hypodermic immunizations,\u0022 says Richard Compans, PhD, Emory professor of microbiology and immunology and one of the paper\u0027s senior authors. \u0022In addition, vaccine delivery into the skin is desirable because of the skin\u0027s rich immune network.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EEven though cutaneous immunization has been shown to induce a broad range of immune responses, and to be especially effective in individuals over age 60, this method has not been widely used because it has not been convenient and has required highly trained personnel.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022Unlike conventional hypodermic injections, microneedles are prepared in a patch for simple administration, possibly by patients themselves, and inserted painlessly onto the skin without specialized training,\u0022 says Mark Prausnitz, PhD, professor in the Georgia Tech School of Chemical and Biomolecular Engineering and co-senior author. \u0022These micron-scale needles can be mass produced using low-cost methods for distribution to doctors\u0027 offices, pharmacies and, possibly, people\u0027s homes.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EOther advantages of the microneedle patches could include more convenient storage, easier transportation and lower dosage requirements. Lower doses could be particularly important because flu vaccine production capacity sometimes is limited for seasonal vaccine, and a future influenza pandemic would require much greater production of vaccine. \n\u003C\/p\u003E\n\u003Cp\u003EReplacing a hypodermic needle with a microneedle patch also could significantly impact the way other vaccines are delivered, and could be particularly beneficial in developing countries. A microneedle patch could fit inside an envelope for delivery by the postal service and would occupy much less storage space. Patches also would increase vaccine safety by reducing the dangers of accidental or intentional hypodermic needle re-use. \n\u003C\/p\u003E\n\u003Cp\u003EThe project team plans future immunization studies in other animal models, including guinea pigs or ferrets, before initiating studies in humans. Also, more studies are needed to determine the minimum vaccine dose needed for full protection. \n\u003C\/p\u003E\n\u003Cp\u003EThe Emory and Georgia Tech research team began developing the new microneedle vaccine patch technology in 2007 using grants from the National Institutes of Health (NIH). The project team has extensive experience in microneedle development, influenza vaccines, vaccine delivery systems, product development and interdisciplinary collaboration.\n\u003C\/p\u003E\n\u003Cp\u003EIn 2007 the NIH awarded a $32.8 million, seven-year contract to Emory, along with the University of Georgia, to establish the Emory\/UGA Influenza Pathogenesis and Immunology Research Center. The center is working to improve the effectiveness of flu vaccines through a number of different projects studying how influenza viruses attack their hosts, how they are transmitted, and what new immune targets might be identified for antiviral medicines.\n\u003C\/p\u003E\n\u003Cp\u003EPrausnitz and his colleagues have been working since the mid 1990s to develop microneedle technology for painless drug and vaccine delivery through the skin. The Georgia Tech team has also developed manufacturing processes for microneedle patches and tested the ability of the needles to deliver proteins, vaccines, nanoparticles, and other small and large molecules through the skin.\n\u003C\/p\u003E\n\u003Cp\u003EOther authors of the papers are Emory microbiologists Ioanna Skountzou and Chinglai Yang, and first authors Ling Ye, Qiyun Zhu, Dimitrios Koutsonanos, and Maria del Pilar Martin from Emory and Vladimir Zarnitsyn from Georgia Tech. Other authors and contributors were Yulong Gao, Lei Pan, and Zhiyuan Wen from Emory, and Harvinder Gill and Sean Sullivan from Georgia Tech.\n\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"New Delivery Method Could Result in Simpler, Safer, Painless Vaccines"}],"field_summary":[{"value":"Flu vaccine delivered through skin patches containing microneedles has proven just as effective at preventing influenza in mice as intramuscular, hypodermic flu immunization.","format":"limited_html"}],"field_summary_sentence":[{"value":"Testing shows microneedle patches are effective for immunization"}],"uid":"27303","created_gmt":"2009-04-28 00:00:00","changed_gmt":"2016-10-08 03:03:14","author":"John Toon","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2009-04-28T00:00:00-04:00","iso_date":"2009-04-28T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"46339":{"id":"46339","type":"image","title":"Research team","body":null,"created":"1449174401","gmt_created":"2015-12-03 20:26:41","changed":"1475894416","gmt_changed":"2016-10-08 02:40:16","alt":"Research team","file":{"fid":"101108","name":"ttf55060.jpg","image_path":"\/sites\/default\/files\/images\/ttf55060_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/ttf55060_0.jpg","mime":"image\/jpeg","size":1505734,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/ttf55060_0.jpg?itok=2pAK5-_4"}},"46340":{"id":"46340","type":"image","title":"Microscope image","body":null,"created":"1449174401","gmt_created":"2015-12-03 20:26:41","changed":"1475894416","gmt_changed":"2016-10-08 02:40:16","alt":"Microscope image","file":{"fid":"101109","name":"tdz55060.jpg","image_path":"\/sites\/default\/files\/images\/tdz55060_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tdz55060_0.jpg","mime":"image\/jpeg","size":304370,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tdz55060_0.jpg?itok=HM98liVO"}},"46341":{"id":"46341","type":"image","title":"Stainless steel microneedles","body":null,"created":"1449174401","gmt_created":"2015-12-03 20:26:41","changed":"1475894416","gmt_changed":"2016-10-08 02:40:16","alt":"Stainless steel microneedles","file":{"fid":"101110","name":"tgi55060.jpg","image_path":"\/sites\/default\/files\/images\/tgi55060_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tgi55060_0.jpg","mime":"image\/jpeg","size":784064,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tgi55060_0.jpg?itok=oa9E0otX"}}},"media_ids":["46339","46340","46341"],"related_links":[{"url":"http:\/\/www.che.gatech.edu\/","title":"School of Chemical and Biomolecular Engineering"},{"url":"http:\/\/www.chbe.gatech.edu\/fac_staff\/faculty\/prausnitz.php","title":"Mark Prausnitz"},{"url":"http:\/\/www.emory.edu\/","title":"Emory University"}],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"135","name":"Research"}],"keywords":[{"id":"764","name":"immunization"},{"id":"765","name":"influenza"},{"id":"494","name":"Microneedle"},{"id":"170850","name":"skin"},{"id":"763","name":"vaccine"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EJohn Toon\u003C\/strong\u003E\u003Cbr \/\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=jt7\u0022\u003EContact John Toon\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-6986\u003C\/strong\u003E","format":"limited_html"}],"email":["jtoon@gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"56372":{"#nid":"56372","#data":{"type":"news","title":"Spring Break with the Pharmaceutical Industry","body":[{"value":"\u003Cp\u003EA group of students from the Georgia Institute of Technology spent spring break (March 18\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Spring Break with the Pharmaceutical Industry","format":"limited_html"}],"field_summary_sentence":[{"value":"A group of students from the Georgia Institute of T"}],"uid":"27224","created_gmt":"2007-07-12 00:00:00","changed_gmt":"2016-10-08 03:06:01","author":"Megan McDevitt","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2007-07-12T00:00:00-04:00","iso_date":"2007-07-12T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"135","name":"Research"},{"id":"150","name":"Physics and Physical Sciences"}],"keywords":[{"id":"9491","name":"bommarius"},{"id":"2780","name":"drug design"},{"id":"9489","name":"pharmcueticals"},{"id":"9490","name":"prausnitz"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EMegan McDevitt\u003C\/strong\u003E\u003Cbr \/\u003EIBB\u003Cbr \/\u003E\u003Ca href=\u0022mailto:mcdevitt@ibb.gatech.edu\u0022\u003EContact Megan McDevitt\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-7001\u003C\/strong\u003E","format":"limited_html"}],"email":["mcdevitt@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}