{"65553":{"#nid":"65553","#data":{"type":"event","title":"Stem Cell Engineering Center Seminar Series","body":[{"value":"\u003Cp\u003EKrishnendu Roy, PhD - University of Texas at Austin\u003C\/p\u003E\u003Cp\u003EAbstract:\u003Cbr \/\u003EBiomaterials and synthetic micro-environments, e.g. scaffolds, bioreactors, drug carriers, etc. can be designed to interact with stem cells and directly influence signaling pathways, differentiation and cell behavior. Most physiological and pathophysiological processes involve complex interactions of cells with their microenvironments.\u0026nbsp; These interactions often vary both spatially and temporally and provide critical, instructive cues to the cells. In this talk we would specifically focus on engineering artificial niches to control stem cell fate. Specifically, we would present results from our effort to (a) generate complex tissues with spatially varying extracellular matrix (ECM) compositions and mechanical properties from a single stem cell population, and (b) generate functional immune cells from embryonic and adult stem cells using biomaterial and bioreactor-based approaches. We will also briefly discuss our work on designing new biomaterial-based delivery systems for cancer therapies.\u003Cbr \/\u003E\u003Cbr \/\u003EBiosketch: \u003Cbr \/\u003EDr. Krishnendu (Krish) Roy received his undergraduate degree from the Indian Institute of Technology (IIT Kharagpur, India) followed by his MS from Boston University and his PhD in Biomedical Engineering from Johns Hopkins University. Following his PhD, he joined Zycos Inc., a start-up biotechnology company where he served first as a Scientist and then as a Senior Scientist in the Drug Delivery Research group.\u0026nbsp; Dr. Roy left his industrial position to join The University of Texas at Austin in 2002, where he is currently the General Dynamics Endowed Faculty Fellow in Engineering, Associate Chair for Education and Outreach and Associate Professor of Biomedical Engineering. Dr. Roy\u2019s research interests are in the areas of stem cell engineering with particular focus on bioreactor cultures and immune cell generation. He is also interested in controlled drug and vaccine delivery technologies and biomedical polymers with applications in cancer and immunotherapies. He was recently elected Fellow of the American Institute for Medical and Biological Engineering (AIMBE). Dr. Roy has received numerous awards and honors including the Young Investigator Awards from both the Controlled Release Society (CRS) and The Society for Biomaterials (SFB), the Young Scientist Award from HSEMB, NSF CAREER award, Global Indus Technovator Award from MIT, the CRS Cygnus Award etc. He has also received the translational research award from the Coulter foundation and the bioengineering grant from the Whitaker Foundation. Dr. Roy\u2019s research has been supported through numerous grants from the NIH and NSF as well as an individual investigator award from the Cancer Prevention and Research Institute of Texas (CPRIT). He serves as a member of the Editorial Boards for the Journal of Controlled Release and the European Journal of Pharmaceutics and Biopharmaceutics.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003ESCEC Seminar Series\u003C\/p\u003E\u003Cp\u003E\u0022Engineering Complex Stem Cell Niches:\u0026nbsp; Generating Therapeutic Cells from Adult and Embryonic Stem Cells\u0022\u003C\/p\u003E\u003Cp\u003EKrishnendu Roy, PhD - University of Texas at Austin\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"\u0022Engineering Complex Stem Cell Niches:  Generating Therapeutic Cells from Adult and Embryonic Stem Cells\u0022 Krishnendu Roy, PhD - University of Texas at Austin"}],"uid":"27195","created_gmt":"2011-04-13 13:12:16","changed_gmt":"2016-10-08 01:54:46","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-04-26T13:00:00-04:00","event_time_end":"2011-04-26T14:00:00-04:00","event_time_end_last":"2011-04-26T14:00:00-04:00","gmt_time_start":"2011-04-26 17:00:00","gmt_time_end":"2011-04-26 18:00:00","gmt_time_end_last":"2011-04-26 18:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"hg_media":{"65552":{"id":"65552","type":"image","title":"Krishnendu Roy, PhD - University of Texas at Austin","body":null,"created":"1449176863","gmt_created":"2015-12-03 21:07:43","changed":"1475894579","gmt_changed":"2016-10-08 02:42:59","alt":"Krishnendu Roy, PhD - University of Texas at Austin","file":{"fid":"192274","name":"Roy_Krish.jpg","image_path":"\/sites\/default\/files\/images\/Roy_Krish_1.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/Roy_Krish_1.jpg","mime":"image\/jpeg","size":13278,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/Roy_Krish_1.jpg?itok=MEFy5N-b"}}},"media_ids":["65552"],"related_links":[{"url":"http:\/\/www.bme.utexas.edu\/faculty\/roy\/index.html","title":"Roy lab"},{"url":"http:\/\/scec.gatech.edu\/","title":"Stem Cell Engineering Center"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"248","name":"IBB"},{"id":"167446","name":"SCEC Seminar"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EMegan Richards\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"65542":{"#nid":"65542","#data":{"type":"event","title":"Biomechanics of Development and Morphogenesis","body":[{"value":"\u003Cp\u003E\u003Cem\u003EIBB Breakfast Club Seminar Series\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EEvan Zamir, PhD\u003C\/strong\u003E - Assistant Professor, School of Mechanical Engineering\u003C\/p\u003E\u003Cp\u003EThe primary mission of Dr. Zamir\u0027s research program is to uncover the biophysical mechanisms that both drive and regulate tissue morphogenesis and cell motility during embryonic development; he uses gastrulation as an experimental system for studying these phenomena. Gastrulation is, perhaps, the fundamental morphogenetic event that occurs during development of higher organisms, as it involves the formation of mesoderm (the middle of the three primary germ layers), which gives rise to vital internal organs, including the heart. Moreover, in recent years, it has become increasingly apparent that many of the genetic regulatory mechanisms that regulate cellular processes during gastrulation play crucial, if not central, roles in abnormal developmental processes that can occur in children or adults \u2014 notably, cancer. Therefore, Dr. Zamir is interested in several areas of human health that, at first glance, may appear unrelated \u2014 heart development, cancer, tissue engineering \u2014 yet involve many of the same fundamental cellular processes and genetic pathways.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe IBB Breakfast Club seminar series was started with the spirit of the Institute\u0027s interdisciplinary mission in mind. The goal of the seminar series is to highlight research taking place throughout the institute to enable the IBB community to further collaborative opportunities and interdisciplinary research. Faculty are often asked to speak at other universities and conferences, but rarely present at their home institution, this seminar series is an attempt to close that gap. The IBB Breakfast Club is open to anyone in the bio-community.\u003C\/p\u003E\u003Cp\u003EContinental breakfast and coffee will be served.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003E\u003Cem\u003EIBB Breakfast Club Seminar Series\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003EEvan Zamir, PhD - Assistant Professor, School of Mechanical Engineering\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Evan Zamir, PhD - Assistant Professor, School of Mechanical Engineering"}],"uid":"27195","created_gmt":"2011-04-13 09:52:32","changed_gmt":"2016-10-08 01:54:46","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-05-10T09:30:00-04:00","event_time_end":"2011-05-10T10:30:00-04:00","event_time_end_last":"2011-05-10T10:30:00-04:00","gmt_time_start":"2011-05-10 13:30:00","gmt_time_end":"2011-05-10 14:30:00","gmt_time_end_last":"2011-05-10 14:30:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"hg_media":{"65800":{"id":"65800","type":"image","title":"IBB Breakfast Club Seminar Series","body":null,"created":"1449176884","gmt_created":"2015-12-03 21:08:04","changed":"1475894582","gmt_changed":"2016-10-08 02:43:02","alt":"IBB Breakfast Club Seminar Series","file":{"fid":"192404","name":"IBB_Breakfast_Club_Logo_2010.jpg","image_path":"\/sites\/default\/files\/images\/IBB_Breakfast_Club_Logo_2010_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/IBB_Breakfast_Club_Logo_2010_0.jpg","mime":"image\/jpeg","size":55737,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/IBB_Breakfast_Club_Logo_2010_0.jpg?itok=uPdPtcAW"}},"65799":{"id":"65799","type":"image","title":"Evan Zamir, PhD - Assistant Professor, School of Mechanical Engineering","body":null,"created":"1449176884","gmt_created":"2015-12-03 21:08:04","changed":"1475894582","gmt_changed":"2016-10-08 02:43:02","alt":"Evan Zamir, PhD - Assistant Professor, School of Mechanical Engineering","file":{"fid":"192403","name":"Zamir.jpg.png","image_path":"\/sites\/default\/files\/images\/Zamir.jpg_0.png","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/Zamir.jpg_0.png","mime":"image\/png","size":250604,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/Zamir.jpg_0.png?itok=WTSZCsnw"}}},"media_ids":["65800","65799"],"related_links":[{"url":"http:\/\/www.me.gatech.edu\/zamirlab\/Home.html","title":"Zamir lab"},{"url":"http:\/\/www.ibb.gatech.edu\/breakfast-club","title":"IBB Breakfast Club"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"11879","name":"BK Club"},{"id":"248","name":"IBB"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EColly Mitchell\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"65543":{"#nid":"65543","#data":{"type":"event","title":"Small RNA Regulation of the Quorum Sensing Response in the Bacterial Pathogen Vibrio Cholerae","body":[{"value":"\u003Cp\u003E\u003Cem\u003EIBB Breakfast Club Seminar Series\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EBrian Hammer, PhD\u003C\/strong\u003E - Assistant Professor, School of Biology\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003EAbstract:\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003EVibrio cholerae\u003C\/em\u003E, the waterborne bacterium\nresponsible for the deadly disease cholera, is both a transient human pathogen\nand a ubiquitous inhabitant of marine environments. The pathogenesis and\necology of this deadly microbe are the focus of research in the Hammer lab. \u003Cem\u003EV.\ncholerae\u003C\/em\u003E has become a model organism to understand a process of microbial\ncell-cell communication called quorum sensing, which allows bacterial groups to\nact in unison by synchronizing gene expression in response to population\ndensity. \u003Cem\u003EV. cholerae\u003C\/em\u003E, and many other \u003Cem\u003EVibrio\u003C\/em\u003E species, achieves\nquorum sensing by producing and then responding to chemical signal molecules,\ncalled autoinducers, which control the production of multiple regulatory small\nRNAs. In \u003Cem\u003EV. cholerae\u003C\/em\u003E, these non-coding sRNAs are predicted to base-pair\nwith, and alter the translation of, several mRNAs encoding protein regulators\nthat alter the expression of \u0026gt;100 genes. Many of the quorum-sensing\nregulated genes (such as the cholera toxin and attachment factors) are critical\nfor host colonization, while others (such as genes involved in horizontal gene\ntransfer) are important in marine ecosystems. We are currently using genetic,\nbiochemical, and computational methods to define the mechanism of sRNA control and\nthe role of \u003Cem\u003EV. cholerae\u003C\/em\u003E quorum sensing in clinical and environmental\nsettings.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe IBB Breakfast Club seminar series was started with the spirit of the Institute\u0027s interdisciplinary mission in mind. The goal of the seminar series is to highlight research taking place throughout the institute to enable the IBB community to further collaborative opportunities and interdisciplinary research. Faculty are often asked to speak at other universities and conferences, but rarely present at their home institution, this seminar series is an attempt to close that gap. The IBB Breakfast Club is open to anyone in the bio-community.\u003C\/p\u003E\u003Cp\u003EContinental breakfast and coffee will be served.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003E\u003Cbr \/\u003E\u003C\/em\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EIBB Breakfast Club Seminar Series\u003C\/p\u003E\u003Cp\u003EBrian Hammer, PhD - Assistant Professor, School of Biology\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Brian Hammer, PhD - Assistant Professor, School of Biology"}],"uid":"27195","created_gmt":"2011-04-13 09:56:41","changed_gmt":"2016-10-08 01:54:46","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-06-14T09:30:00-04:00","event_time_end":"2011-06-14T10:30:00-04:00","event_time_end_last":"2011-06-14T10:30:00-04:00","gmt_time_start":"2011-06-14 13:30:00","gmt_time_end":"2011-06-14 14:30:00","gmt_time_end_last":"2011-06-14 14:30:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"hg_media":{"65800":{"id":"65800","type":"image","title":"IBB Breakfast Club Seminar Series","body":null,"created":"1449176884","gmt_created":"2015-12-03 21:08:04","changed":"1475894582","gmt_changed":"2016-10-08 02:43:02","alt":"IBB Breakfast Club Seminar Series","file":{"fid":"192404","name":"IBB_Breakfast_Club_Logo_2010.jpg","image_path":"\/sites\/default\/files\/images\/IBB_Breakfast_Club_Logo_2010_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/IBB_Breakfast_Club_Logo_2010_0.jpg","mime":"image\/jpeg","size":55737,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/IBB_Breakfast_Club_Logo_2010_0.jpg?itok=uPdPtcAW"}},"65805":{"id":"65805","type":"image","title":"Brian Hammer, PhD - Assistant Professor, School of Biology","body":null,"created":"1449176884","gmt_created":"2015-12-03 21:08:04","changed":"1475894582","gmt_changed":"2016-10-08 02:43:02","alt":"Brian Hammer, PhD - Assistant Professor, School of Biology","file":{"fid":"192408","name":"Hammer.jpg","image_path":"\/sites\/default\/files\/images\/Hammer_1.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/Hammer_1.jpg","mime":"image\/jpeg","size":8705,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/Hammer_1.jpg?itok=PtE7wxj1"}}},"media_ids":["65800","65805"],"related_links":[{"url":"http:\/\/www.ibb.gatech.edu\/brian-hammer","title":"Brian Hammer profile"},{"url":"http:\/\/www.ibb.gatech.edu\/breakfast-club","title":"IBB Breakfast Club"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"11879","name":"BK Club"},{"id":"248","name":"IBB"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EColly Mitchell\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"65544":{"#nid":"65544","#data":{"type":"event","title":"Social Biology of Insects - IBB Breakfast Club Seminar Series","body":[{"value":"\u003Cp\u003E\u003Cem\u003EIBB Breakfast Club Seminar Series\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EMichael Goodisman, PhD\u003C\/strong\u003E - Associate Professor, School of Biology\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003E\u0022Social Biology of Insects\u0022\u003C\/em\u003E\u003Cem\u003E\u0026nbsp;\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003EAbstract\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003E\u0026nbsp;\u003C\/em\u003EBiological complexity has increased through a series of major evolutionary transitions.\u0026nbsp; One of the most recent transitions occurred when individually reproducing organisms came together to form integrated social groups.\u0026nbsp; The transition to sociality is best exemplified by the social insects, such as ants, social bees, social wasps, and termites.\u0026nbsp; Social insects have been ranked as \u2018among the greatest achievements of organic evolution\u2019 because of the extraordinary levels of cooperation.\u0026nbsp; In addition, social insects have been extremely successful ecologically.\u0026nbsp; In this presentation, I will introduce the life history strategies and evolutionary significance of social insects.\u0026nbsp; I will then discuss aspects of research within my group aimed at understanding the molecular basis underlying sociality, the nature of selection in social systems, the breeding biology of social animals, and the process of self-organization in social groups.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe IBB Breakfast Club seminar series was started with the spirit of the Institute\u0027s interdisciplinary mission in mind. The goal of the seminar series is to highlight research taking place throughout the institute to enable the IBB community to further collaborative opportunities and interdisciplinary research. Faculty are often asked to speak at other universities and conferences, but rarely present at their home institution, this seminar series is an attempt to close that gap. The IBB Breakfast Club is open to anyone in the bio-community.\u003C\/p\u003E\u003Cp\u003EContinental breakfast and coffee will be served.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EIBB Breakfast Club Seminar\u003C\/p\u003E\u003Cp\u003EMichael Goodisman, PhD - Associate Professor, School of Biology\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Michael Goodisman, associate professor of biology, will speak."}],"uid":"27195","created_gmt":"2011-04-13 09:58:32","changed_gmt":"2016-10-08 01:54:46","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-07-12T09:30:00-04:00","event_time_end":"2011-07-12T10:30:00-04:00","event_time_end_last":"2011-07-12T10:30:00-04:00","gmt_time_start":"2011-07-12 13:30:00","gmt_time_end":"2011-07-12 14:30:00","gmt_time_end_last":"2011-07-12 14:30:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"hg_media":{"65800":{"id":"65800","type":"image","title":"IBB Breakfast Club Seminar Series","body":null,"created":"1449176884","gmt_created":"2015-12-03 21:08:04","changed":"1475894582","gmt_changed":"2016-10-08 02:43:02","alt":"IBB Breakfast Club Seminar Series","file":{"fid":"192404","name":"IBB_Breakfast_Club_Logo_2010.jpg","image_path":"\/sites\/default\/files\/images\/IBB_Breakfast_Club_Logo_2010_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/IBB_Breakfast_Club_Logo_2010_0.jpg","mime":"image\/jpeg","size":55737,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/IBB_Breakfast_Club_Logo_2010_0.jpg?itok=uPdPtcAW"}},"65801":{"id":"65801","type":"image","title":"Michael Goodisman, PhD - Assistant Professor, School of Biology","body":null,"created":"1449176884","gmt_created":"2015-12-03 21:08:04","changed":"1475894582","gmt_changed":"2016-10-08 02:43:02","alt":"Michael Goodisman, PhD - Assistant Professor, School of Biology","file":{"fid":"192405","name":"Goodisman.jpg","image_path":"\/sites\/default\/files\/images\/Goodisman_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/Goodisman_0.jpg","mime":"image\/jpeg","size":17386,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/Goodisman_0.jpg?itok=X-F34AoE"}}},"media_ids":["65800","65801"],"related_links":[{"url":"http:\/\/www.ibb.gatech.edu\/michael-goodisman","title":"Goodisman profile"},{"url":"http:\/\/www.ibb.gatech.edu\/breakfast-club","title":"IBB Breakfast Club"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"11879","name":"BK Club"},{"id":"248","name":"IBB"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EColly Mitchell\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"65547":{"#nid":"65547","#data":{"type":"event","title":"IBB Breakfast Club Seminar - Medical Decision Making: A Machine Learning Framework for Classification in Medicine and Biology","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EEva Lee, PhD\u003C\/strong\u003E - Director, Center for Operations Research in Medicine and HealthCare, Professor, School of Industrial and Systems Engineering\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003EAbstract\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003ESystems modeling and quantitative analysis of large amounts of complex clinical and biological data may help to identify discriminatory patterns that can uncover health risks, detect early disease formation, monitor treatment and prognosis, and predict treatment outcome. In this talk, we describe a machine-learning framework for medical decision making. It consists of a pattern recognition module, a feature selection module, and a classification modeler and solver. The pattern recognition module involves automatic image analysis, genomic pattern recognition, and spectrum pattern extractions. The feature selection module consists of a combinatorial selection algorithm where discriminatory patterns are extracted from among a large set of pattern attributes. These modules are wrapped around the classification modeler and solver into a machine learning framework. The classification modeler and solver consist of novel optimization-based predictive models that maximize the correct classification while constraining the inter-group misclassifications. The classification\/predictive models 1)have the ability to classify any number of distinct groups; 2) allow incorporation of heterogeneous, and continuous\/time-dependent types of attributes as input; 3) utilize a high-dimensional data transformation that minimizes noise and errors in biological and clinical data; 4) incorporate a reserved-judgement region that provides a safeguard against over-training; and 5) have successive multi-stage classification capability.\u003C\/p\u003E\n\u003Cp\u003ESuccessful applications of our model to developing rules for gene silencing in cancer cells, predicting the immunity of vaccines, identifying the cognitive status of individuals, and predicting metabolite concentrations in humans will be discussed. We acknowledge our clinical\/biological collaborators: Dr. Vertino (Winship Cancer Institute, Emory), Drs. Pulendran and Ahmed (Emory Vaccine Center), Dr. Levey (Neurodegenerative Disease and Alzheimer\u2019s Disease), and Dr. Jones (Clinical Biomarkers, Emory).\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe IBB Breakfast Club seminar series was started with the spirit of the Institute\u0027s interdisciplinary mission in mind. The goal of the seminar series is to highlight research taking place throughout the institute to enable the IBB community to further collaborative opportunities and interdisciplinary research. Faculty are often asked to speak at other universities and conferences, but rarely present at their home institution, this seminar series is an attempt to close that gap. The IBB Breakfast Club is open to anyone in the bio-community.\u003C\/p\u003E\n\u003Cp\u003E\u003Cem\u003EContinental breakfast and coffee will be served.\u003C\/em\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EIBB Breakfast Club Seminar Series\u003C\/p\u003E\u003Cp\u003EEva Lee, PhD - Director, Center for Operations Research in Medicine and HealthCare, Professor, School of Industrial and Systems Engineering\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Eva Lee, PhD - Director, Center for Operations Research in Medicine and HealthCare, Professor, School of Industrial and Systems Engineering"}],"uid":"27195","created_gmt":"2011-04-13 10:26:59","changed_gmt":"2016-10-08 01:54:46","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-08-09T09:30:00-04:00","event_time_end":"2011-08-09T10:30:00-04:00","event_time_end_last":"2011-08-09T10:30:00-04:00","gmt_time_start":"2011-08-09 13:30:00","gmt_time_end":"2011-08-09 14:30:00","gmt_time_end_last":"2011-08-09 14:30:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"hg_media":{"65800":{"id":"65800","type":"image","title":"IBB Breakfast Club Seminar Series","body":null,"created":"1449176884","gmt_created":"2015-12-03 21:08:04","changed":"1475894582","gmt_changed":"2016-10-08 02:43:02","alt":"IBB Breakfast Club Seminar Series","file":{"fid":"192404","name":"IBB_Breakfast_Club_Logo_2010.jpg","image_path":"\/sites\/default\/files\/images\/IBB_Breakfast_Club_Logo_2010_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/IBB_Breakfast_Club_Logo_2010_0.jpg","mime":"image\/jpeg","size":55737,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/IBB_Breakfast_Club_Logo_2010_0.jpg?itok=uPdPtcAW"}},"65804":{"id":"65804","type":"image","title":"Eva Lee, PhD - Professor, School of Industrial \u0026 Systems Engineering","body":null,"created":"1449176884","gmt_created":"2015-12-03 21:08:04","changed":"1475894582","gmt_changed":"2016-10-08 02:43:02","alt":"Eva Lee, PhD - Professor, School of Industrial \u0026 Systems Engineering","file":{"fid":"192407","name":"Eva_Lee.jpg","image_path":"\/sites\/default\/files\/images\/Eva_Lee_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/Eva_Lee_0.jpg","mime":"image\/jpeg","size":50370,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/Eva_Lee_0.jpg?itok=iSl_f0vG"}}},"media_ids":["65800","65804"],"related_links":[{"url":"http:\/\/www.isye.gatech.edu\/faculty-staff\/profile.php?entry=el44","title":"Eva Lee"},{"url":"http:\/\/www.ibb.gatech.edu\/breakfast-club","title":"IBB Breakfast Club"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"11879","name":"BK Club"},{"id":"1043","name":"eva lee"},{"id":"248","name":"IBB"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EColly Mitchell\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"65663":{"#nid":"65663","#data":{"type":"event","title":"2011 IBB Distinguished Lecture","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003E\u0022Investigation of Human Diseases at the Intersections of Engineering, Natural Sciences and Medicine\u0022\n\u003Cbr \/\u003E\n\u003Cbr \/\u003ESubra Suresh - Director, United States National Science Foundation\n\n\u003C\/strong\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cem\u003EAbstract:\n\u003C\/em\u003E\u003Cbr \/\u003EMajor advances in various branches of engineering and natural sciences, together with transformational developments in information technology, computational modeling and simulation, genetics, genomics, and nanotechnology, have provided unprecedented opportunities to explore human health and diseases at the cellular and molecular levels.  Such developments have also facilitated new opportunities to study fundamental mechanistic processes with the goal of developing basic scientific understanding, new diagnostic tools, and novel therapeutics for a range of human diseases and disorders.  This presentation will provides an overview of some recent accomplishments and opportunities for future exploration.  Specific examples are drawn from the study of infectious diseases, hereditary blood disorders, and cancer.\n\n\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cem\u003EBiography:\u003C\/em\u003E\u003Cbr \/\u003ESubra Suresh was sworn in as director of the National Science Foundation on October 18, 2010, and is the Vannevar Bush Professor of Engineering (on leave) at the Massachusetts Institute of Technology. He holds joint faculty appointments in Materials Science and Engineering, Mechanical Engineering, Biological Engineering, and Health Sciences and Technology. \n\nSuresh\u2019s work as a researcher, educator, and academic administrator across a wide range of disciplines\u2014including mechanical engineering, materials science, and biomedical engineering\u2014have been recognized by academic and professional organizations around the world. His experimental and computational modeling work on the mechanical properties of structural and functional materials, his innovations in materials design and characterization, and his discoveries regarding the connections between cellular nanomechanics and human diseases such as malaria have shaped new fields at the intersections of traditional disciplines. More than 100 students, post-doctoral associates, and research scientists who trained in his group occupy prominent positions in academe, industry, and government throughout the world. He has authored or co-authored three books: Fatigue of Materials, Fundamentals of Functionally Graded Materials, and Thin Film Materials.  \n\nSuresh made far-reaching contributions as a graduate student, parent, faculty member, and dean over three decades at MIT. While serving as department head in Materials Science and Engineering from 2000 to 2006, he renovated highly visible spaces along the Infinite Corridor to give the general public an insider\u2019s view of modern materials research and instruction, and, in partnership with the Physics Department, he helped launch the Physics-DMSE-Spectroscopy-Infrastructure (PDSI) project. Suresh was founding chair of the first Singapore-MIT Alliance (SMA) Programme on Advanced Materials for Micro and Nano Systems and was the Institute\u2019s lead coordinator on the creation of the Singapore-MIT Alliance for Research and Technology (SMART) Center. Suresh\u2019s interests in international, inter-institutional, and inter-disciplinary collaboration led in 2005 to the creation of Global Enterprise for MicroMechanics and Molecular Medicine (GEM4), whose membership now includes more than 12 institutions from around the world.\n\nDuring Suresh\u2019s tenure as Dean the School of Engineering added more than 50 new faculty members to its ranks\u2014more than 10% of its total. Under his leadership, the School pioneered new interdepartmental faculty searches and recruited high numbers of women and under-represented minorities to the faculty; in 2009-10, for the first time in its history, more women than men joined the faculty of MIT\u2019s School of Engineering. Suresh also oversaw the creation of a several new initiatives: the Center for Computational Engineering, the Transportation@MIT initiative, the Bernard Gordon Engineering Leadership Program, the creation and renovation of a number of laboratory facilities, and the MIT Flexible Engineering Degree Program.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003E2011 IBB Distinguished Lecture -\u0026nbsp;Subra Suresh, PhD - Director, National Science Foundation\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"\u0022Investigation of Human Diseases at the Intersections of Engineering, Natural Sciences and Medicine\u0022 - Subra Suresh, PhD - Director National Science Foundation"}],"uid":"27195","created_gmt":"2011-04-19 12:20:49","changed_gmt":"2016-10-08 01:54:50","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-09-20T12:00:00-04:00","event_time_end":"2011-09-20T14:30:00-04:00","event_time_end_last":"2011-09-20T14:30:00-04:00","gmt_time_start":"2011-09-20 16:00:00","gmt_time_end":"2011-09-20 18:30:00","gmt_time_end_last":"2011-09-20 18:30:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"hg_media":{"65664":{"id":"65664","type":"image","title":"Subra Suresh, PhD - Director, National Science Foundation","body":null,"created":"1449176863","gmt_created":"2015-12-03 21:07:43","changed":"1475894582","gmt_changed":"2016-10-08 02:43:02","alt":"Subra Suresh, PhD - Director, National Science Foundation","file":{"fid":"192294","name":"Suresh_Subra.jpg","image_path":"\/sites\/default\/files\/images\/Suresh_Subra_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/Suresh_Subra_0.jpg","mime":"image\/jpeg","size":50897,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/Suresh_Subra_0.jpg?itok=2HOimKIv"}}},"media_ids":["65664"],"related_links":[{"url":"http:\/\/nanomechanics.mit.edu\/","title":"Suresh lab"},{"url":"http:\/\/www.nsf.gov\/","title":"National Science Foundation"},{"url":"http:\/\/www.ibb.gatech.edu\/","title":"Petit Institute for Bioengineering and Bioscience"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"13266","name":"2011 IBB Distinguished Lecturer"},{"id":"248","name":"IBB"},{"id":"363","name":"NSF"},{"id":"167492","name":"Subra Suresh"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EMegan McDevitt\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"65424":{"#nid":"65424","#data":{"type":"event","title":"IBB Industry Partner\u0027s Symposium","body":[{"value":"\u003Cp\u003EJoin us to see the latest research taking place in the areas of regenerative medicine and pharmaceuticals on the Georgia Tech campus. The symposium provides a unique environment for industry interactions with science, engineering, and clinical faculty and students generating new potential technologies.\u003Cbr \/\u003E\u003Cbr \/\u003EThe annual fall Industry Partners Symposium is a premier benefit of the IBB Industry Partners Program.\u0026nbsp; The symposium provides our partners with updates on the latest advances in regenerative medicine and pharmaceutical research through oral and poster presentations.\u0026nbsp; There is plenty of time for interactions with faculty and students and one-on-one meetings can be pre-arranged.\u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022http:\/\/ips.gatech.edu\/2011-program\u0022\u003E2011 Industry Partners\u0027 Symposium program\u003C\/a\u003E\u003C\/p\u003E\u003Cp\u003EFor more information, contact\u0026nbsp;\u003Ca href=\u0022mailto:megan.mcdevitt@ibb.gatech.edu\u0022\u003EMegan McDevitt\u003C\/a\u003E, Marketing and Event Manager, IBB\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EJoin us to see the latest research taking place in the areas of\nregenerative medicine and pharmaceuticals on the Georgia Tech campus.\nThe symposium provides a unique environment for industry interactions\nwith science, engineering, and clinical faculty and students generating\nnew potential technologies.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Join us to see the latest research taking place in the areas of regenerative medicine and pharmaceuticals on the Georgia Tech campus"}],"uid":"27224","created_gmt":"2011-04-07 10:30:26","changed_gmt":"2016-10-08 01:54:42","author":"Megan McDevitt","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-11-10T07:00:00-05:00","event_time_end":"2011-11-11T16:00:00-05:00","event_time_end_last":"2011-11-11T16:00:00-05:00","gmt_time_start":"2011-11-10 12:00:00","gmt_time_end":"2011-11-11 21:00:00","gmt_time_end_last":"2011-11-11 21:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"248","name":"IBB"},{"id":"12693","name":"Industry Partners"},{"id":"7031","name":"pharmaceutical"},{"id":"1489","name":"Regenerative Medicine"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1789","name":"Conference\/Symposium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:mcdevitt@ibb.gatech.edu\u0022\u003EMegan McDevitt\u003C\/a\u003E,\u0026nbsp;Marketing and Event Manager\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}