{"132331":{"#nid":"132331","#data":{"type":"news","title":"ATDC Graduates Eight Companies at 2012 Showcase Event","body":[{"value":"\u003Cp\u003EBuoyed by encouraging words from Georgia Tech officials, an economic development expert and Georgia\u2019s State Senate majority leader, eight local startup companies graduated from the Advanced Technology Development Center (ATDC) on May 14. The graduation ceremonies were part of ATDC\u2019s 2012 Startup Showcase, held at the Georgia Tech Hotel and Conference Center.\u003C\/p\u003E\u003Cp\u003EPart of Georgia Tech\u2019s Enterprise Innovation Institute, ATDC is a startup accelerator that helps Georgia entrepreneurs launch and build successful technology companies. Each year, member companies that have met rigorous growth milestones are selected to graduate.\u003C\/p\u003E\u003Cp\u003ECalling ATDC \u201cthe flagship\u201d of the institute\u2019s economic development programs, Georgia Tech President G.P. \u201cBud\u201d Peterson praised the level of support the center offers emerging firms. \u201cSuccess is seldom a one-man enterprise,\u201d he said. \u201cThese companies can now go on to be tremendously successful.\u201d\u003C\/p\u003E\u003Cp\u003EStephen Fleming, a Georgia Tech vice president and executive director of the Enterprise Innovation Institute, outlined ATDC\u2019s history and noted the recent expansion of the entrepreneur-in-residence program, which gives member companies access to CEOs and others who have successfully created their own startup firms.\u003C\/p\u003E\u003Cp\u003E\u201cWe are making use of a lot of the resources from our community,\u201d Fleming said.\u003C\/p\u003E\u003Cp\u003EBill Cronin, vice president of economic development for Invest Atlanta, told the graduating firms they and other companies like them are a vital part of the city\u2019s business culture. \u201cLast year, the companies that were incubated at Georgia Tech directly represented $84 million annually to our local economy,\u201d Cronin said.\u003C\/p\u003E\u003Cp\u003E\u201cThis is only a start, as these companies ripen and mature, they will make money and hopefully reinvest in their businesses and our economy,\u201d Cronin added. \u201cThey will cross-pollinate and create new strains of technology, industry hybrids and innovative business ideas.\u201d\u003C\/p\u003E\u003Cp\u003EState Senate Majority Leader Chip Rogers (R-Woodstock), a 1991 graduate of Georgia Tech, said the eight firms are \u201ca microcosm of what America is all about: innovation, free markets and entrepreneurship.\u201d\u003C\/p\u003E\u003Cp\u003ENina Sawczuk, general manager of the ATDC, mentioned the two new community catalysts \u2013 Jennifer Bonnett and Chip Schooler \u2013 and detailed results of a new survey of ATDC member companies that indicated 98 percent of members would recommend the program to other startups.\u003C\/p\u003E\u003Cp\u003EThe 2012 ATDC graduates included:\u003C\/p\u003E\u003Cul\u003E\u003Cli\u003E\u003Cstrong\u003E3DM Systems\u003C\/strong\u003E (formerly ShapeStart Measurement Systems), which produces an in-ear, three-dimensional scanner for the digital design of custom hearing aids and ear molds.\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003EAsankya\u003C\/strong\u003E (which has been acquired by EMC Corporation), a provider of technologies used by firms offering computer cloud storage.\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003EAxion BioSystems\u003C\/strong\u003E, which makes products used for neural and cardiac toxicology testing and the screening of potential drug compounds by pharmaceutical companies.\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003EBioAutomaton Systems Inc\u003C\/strong\u003E., which designs and manufactures patented automation systems for cost-effective propagation of transgenic tree seedlings.\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003ECeltaxsys\u003C\/strong\u003E, which is focused on the discovery and development of therapeutics to treat inflammation by controlling innate immunity.\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003EDigital Assent\u003C\/strong\u003E, whose technology delivers personalized health information and advertising to consumers in doctors\u2019 waiting rooms and at home.\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003EPreparis\u003C\/strong\u003E, which provides a web-based series of services and apps that build corporate emergency preparedness and security.\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003ESimpleC\u003C\/strong\u003E, which produces technologies that deliver cognitive therapies to those suffering from dementia.\u003C\/li\u003E\u003C\/ul\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EOn the Floor\u003C\/strong\u003E\u003Cbr \/\u003EGraduation wasn\u2019t the only component of the 2012 Startup Showcase. After the formal ceremony, event attendees moved to an exhibit hall featuring 45 ATDC member companies and Georgia Tech researchers displaying their products and technologies.\u003C\/p\u003E\u003Cp\u003ESteve Dickerson, founder and CEO of exhibitor SoftWear Automation, which produces technology that automates the sewing of garments, said his booth was experiencing a healthy amount of traffic.\u003C\/p\u003E\u003Cp\u003EHe also had praise for ATDC, from which two of his other startup companies have graduated. \u201cIt\u2019s the whole level of support [ATDC gives] you,\u201d Dickerson said. \u201cI\u2019ve leaned on ATDC to come up with everything from ideas on investors to company names. I\u2019m pretty darn pleased.\u201d\u003C\/p\u003E\u003Cp\u003EA half dozen Georgia Tech researchers also showed the technologies they were developing:\u003C\/p\u003E\u003Cul\u003E\u003Cli\u003EDouglas Cox, George W. Woodruff School of Mechanical Engineering: Solar Car.\u003C\/li\u003E\u003Cli\u003EMaysam Ghovanloo, School of Electrical and Computer Engineering: Tongue Drive System.\u003C\/li\u003E\u003Cli\u003ETanya Marlow, School of Interactive Computing: Mobile Music Touch Glove.\u003C\/li\u003E\u003Cli\u003EJayant Ratti, School of Electrical and Computer Engineering: Robotic Insects.\u003C\/li\u003E\u003Cli\u003EPatricio Vela, School of Electrical and Computer Engineering: Robotic Arm.\u003C\/li\u003E\u003Cli\u003EGil Weinberg, Center for Music Technology: Robot Travis.\u003C\/li\u003E\u003C\/ul\u003E\u003Cp\u003E\u003Cstrong\u003EAbout ATDC\u003C\/strong\u003E: The Advanced Technology Development Center (ATDC) serves as the hub for technology entrepreneurship in Georgia. Founded in 1980, ATDC helps Georgia entrepreneurs launch and build successful technology companies by providing coaching, connections, and community. Through business incubation and acceleration services, ATDC has supported the creation of hundreds of technology companies that together have raised more than a billion dollars in outside financing. Headquartered in Atlanta\u2019s Technology Square, ATDC members benefit from a close proximity to Georgia Tech and connections with other Georgia research universities. ATDC was named one of the \u201c10 technology incubators that are changing the world\u201d by Forbes Magazine in 2010.\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EEnterprise Innovation Institute\u003C\/strong\u003E\u003Cbr \/\u003E\u003Cstrong\u003EGeorgia Institute of Technology\u003C\/strong\u003E\u003Cbr \/\u003E\u003Cstrong\u003E75 Fifth Street, N.W., Suite 314\u003C\/strong\u003E\u003Cbr \/\u003E\u003Cstrong\u003EAtlanta, Georgia 30308 USA\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EMedia Relations Contacts\u003C\/strong\u003E: John Toon (404-894-6986)(\u003Ca href=\u0022mailto:jtoon@gatech.edu\u0022\u003Ejtoon@gatech.edu\u003C\/a\u003E) or Abby Robinson (404-385-3364)(\u003Ca href=\u0022mailto:abby@innovate.gatech.edu\u0022\u003Eabby@innovate.gatech.edu\u003C\/a\u003E).\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EWriter\u003C\/strong\u003E: Stephen Ursery\u003Cbr \/\u003E\u003Cbr \/\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EBuoyed by encouraging words from Georgia Tech officials, an economic development expert and Georgia\u2019s State Senate majority leader, eight local startup companies graduated from the Advanced Technology Development Center (ATDC) on May 14. The graduation ceremonies were part of ATDC\u2019s 2012 Startup Showcase, held at the Georgia Tech Hotel and Conference Center.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"ATDC, Georgia Tech\u0027s business incubator, graduated eight companies at its 2012 showcase event."}],"uid":"27303","created_gmt":"2012-05-22 17:49:21","changed_gmt":"2016-10-08 03:12:18","author":"John Toon","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2012-05-22T00:00:00-04:00","iso_date":"2012-05-22T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"132301":{"id":"132301","type":"image","title":"ATDC 2012 Graduates","body":null,"created":"1449178659","gmt_created":"2015-12-03 21:37:39","changed":"1475894759","gmt_changed":"2016-10-08 02:45:59","alt":"ATDC 2012 Graduates","file":{"fid":"194710","name":"atdc-2012-grads.jpg","image_path":"\/sites\/default\/files\/images\/atdc-2012-grads_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/atdc-2012-grads_0.jpg","mime":"image\/jpeg","size":2046364,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/atdc-2012-grads_0.jpg?itok=NqiEOGVg"}},"132311":{"id":"132311","type":"image","title":"ATDC 2012 Showcase - President Peterson","body":null,"created":"1449178659","gmt_created":"2015-12-03 21:37:39","changed":"1475894759","gmt_changed":"2016-10-08 02:45:59","alt":"ATDC 2012 Showcase - President Peterson","file":{"fid":"194711","name":"peterson-remarks.jpg","image_path":"\/sites\/default\/files\/images\/peterson-remarks_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/peterson-remarks_0.jpg","mime":"image\/jpeg","size":2288709,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/peterson-remarks_0.jpg?itok=M7ohSCix"}},"132321":{"id":"132321","type":"image","title":"ATDC 2912 Showcase - Dennis  Hayes","body":null,"created":"1449178659","gmt_created":"2015-12-03 21:37:39","changed":"1475894759","gmt_changed":"2016-10-08 02:45:59","alt":"ATDC 2912 Showcase - Dennis  Hayes","file":{"fid":"194712","name":"hayes-peterson-fleming.jpg","image_path":"\/sites\/default\/files\/images\/hayes-peterson-fleming_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/hayes-peterson-fleming_0.jpg","mime":"image\/jpeg","size":1476072,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/hayes-peterson-fleming_0.jpg?itok=D_A3jYKk"}}},"media_ids":["132301","132311","132321"],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"131","name":"Economic Development and Policy"}],"keywords":[{"id":"9193","name":"accelerator"},{"id":"4238","name":"atdc"},{"id":"3671","name":"Enterprise Innovation Institute"},{"id":"4239","name":"incubator"},{"id":"167668","name":"Stephen Fleming"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EJohn Toon\u003C\/p\u003E\u003Cp\u003EResearch News \u0026amp; Publications Office\u003C\/p\u003E\u003Cp\u003E(404) 894-6986\u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022mailto:jtoon@gatech.edu\u0022\u003Ejtoon@gatech.edu\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["jtoon@gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"73128":{"#nid":"73128","#data":{"type":"external_news","title":"Atlanta ranked as an emerging life sciences market","body":[{"value":"\u003Cp\u003EJones Lang LaSalle said Monday Atlanta is among the top U.S. markets for life science companies, including those working in biotechnology, pharmaceuticals, biofuels and medical devices.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27195","created_gmt":"2011-11-29 14:18:16","changed_gmt":"2016-10-08 02:25:13","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","publication":"breakthrough cases","field_article_url":"","publication_url":"http:\/\/www.bizjournals.com\/atlanta\/news\/2011\/11\/28\/atlanta-ranked-as-an-emerging-life.html","dateline":{"date":"2011-11-28T00:00:00-05:00","iso_date":"2011-11-28T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"134","name":"Student and Faculty"}],"keywords":[{"id":"15200","name":"atlanta ranked as emerging life sciences market"},{"id":"109","name":"Georgia Tech"},{"id":"248","name":"IBB"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"72308":{"#nid":"72308","#data":{"type":"external_news","title":"Georgia has No. 2 business climate in U.S.","body":[{"value":"\u003Cp\u003EMagazine lists of all kinds that rank cities and states often draw a skeptical response from people who question their methodology or real value. \u0026nbsp;But a new ranking of Georgia as having the second-best business climate in the U.S. should have a positive impact on efforts to attract companies and jobs here, a top state development official said.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27195","created_gmt":"2011-11-02 14:29:19","changed_gmt":"2016-10-08 02:25:13","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","publication_url":"http:\/\/www.ajc.com\/business\/magazine-georgia-has-no-1214815.html","dateline":{"date":"2011-11-01T00:00:00-04:00","iso_date":"2011-11-01T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"14970","name":"Georgia has No. 2 business climate in U.S."}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"71711":{"#nid":"71711","#data":{"type":"news","title":"Hold Your Forces: Mechanical Stress Can Help or Hinder Wound Healing Depending on Time of Application","body":[{"value":"\u003Cp\u003EA new study demonstrates that mechanical forces affect the growth and remodeling of blood vessels during tissue regeneration and wound healing. The forces diminish or enhance the vascularization process and tissue regeneration depending on when they are applied during the healing process.\u003C\/p\u003E\u003Cp\u003EThe study found that applying mechanical forces to an injury site immediately after healing began disrupted vascular growth into the site and prevented bone healing. However, applying mechanical forces later in the healing process enhanced functional bone regeneration. The study\u2019s findings could influence treatment of tissue injuries and recommendations for rehabilitation.\u003C\/p\u003E\u003Cp\u003E\u201cOur finding that mechanical stresses caused by movement can disrupt the initial formation and growth of new blood vessels supports the advice doctors have been giving their patients for years to limit activity early in the healing process,\u201d said Robert Guldberg, a professor in the George W. Woodruff School of Mechanical Engineering at the Georgia Institute of Technology. \u201cHowever, our findings also suggest applying mechanical stresses to the wound later on can significantly improve healing through a process called adaptive remodeling.\u201d\u003C\/p\u003E\u003Cp\u003EThe study was published last month in the journal Proceedings of the National Academy of Sciences. The research was supported by the National Institutes of Health, the Armed Forces Institute of Regenerative Medicine and the U.S. Department of Defense.\u003C\/p\u003E\u003Cp\u003EBecause blood vessel growth is required for the regeneration of many different tissues, including bone, Guldberg and former Georgia Tech graduate student Joel Boerckel used healing of a bone defect in rats for their study. Following removal of eight millimeters of femur bone, they treated the gap with a polymer scaffold seeded with a growth factor called recombinant human bone morphogenetic protein-2 (rhBMP-2), a potent inducer of bone regeneration. The scaffold was designed in collaboration with Nathaniel Huebsch and David Mooney from Harvard University.\u003C\/p\u003E\u003Cp\u003EIn one group of animals, plates screwed onto the bones to maintain limb stability prevented mechanical forces from being applied to the affected bone. In another group, plates allowed compressive loads along the bone axis to be transferred, but prevented twisting and bending of the limbs. The researchers used contrast-enhanced micro-computed tomography imaging and histology to quantify new bone and blood vessel formation.\u003C\/p\u003E\u003Cp\u003EThe experiments showed that exerting mechanical forces on the injury site immediately after healing began significantly inhibited vascular growth into the bone defect region. The volume of blood vessels and their connectivity were reduced by 66 and 91 percent, respectively, compared to the group for which no force was applied. The lack of vascular growth into the defect produced a 75 percent reduction in bone formation and failure to heal the defect.\u003C\/p\u003E\u003Cp\u003EBut the study found that the same mechanical force that hindered repair early in the healing process became helpful later on.\u003C\/p\u003E\u003Cp\u003EWhen the injury site experienced no mechanical force until four weeks after the injury, blood vessels grew into the defect and vascular remodeling began. With delayed loading, the researchers observed a reduction in quantity and connectivity of blood vessels, but the average vessel thickness increased. In addition, bone formation improved by 20 percent compared to when no force was applied, and strong tissue biomaterial integration was evident.\u003C\/p\u003E\u003Cp\u003E\u201cWe found that having a very stable environment initially is very important because mechanical stresses applied early on disrupted very small vessels that were forming,\u201d said Guldberg, who is also the director of the Petit Institute for Bioengineering and Bioscience at Georgia Tech. \u201cIf you wait until those vessels have grown in and they\u2019re a little more mature, applying a mechanical stimulus then induces remodeling so that you end up with a more robust vascular network.\u201d\u003C\/p\u003E\u003Cp\u003EThe study\u2019s results may help researchers optimize the mechanical properties of tissue regeneration scaffolds in the future.\u003C\/p\u003E\u003Cp\u003E\u201cOur study shows that one might want to implant a material that is stiff at the very beginning to stabilize the injury site but becomes more compliant with time, to improve vascularization and tissue regeneration,\u201d added Guldberg.\u003C\/p\u003E\u003Cp\u003EGeorgia Tech mechanical engineering graduate student Brent Uhrig and postdoctoral fellow Nick Willett also contributed to this research.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"A new study demonstrates that mechanical forces affect the growth and remodeling of blood vessels during tissue regeneration and wound healing."}],"field_summary":"","field_summary_sentence":[{"value":"A new study demonstrates that mechanical forces affect the growth and remodeling of blood vessels during tissue regeneration and wound healing."}],"uid":"27224","created_gmt":"2011-10-24 10:03:56","changed_gmt":"2016-10-08 03:10:34","author":"Megan McDevitt","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-10-24T00:00:00-04:00","iso_date":"2011-10-24T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"71712":{"id":"71712","type":"image","title":"Guldberg Research Image","body":null,"created":"1449177396","gmt_created":"2015-12-03 21:16:36","changed":"1475894642","gmt_changed":"2016-10-08 02:44:02","alt":"Guldberg Research Image","file":{"fid":"193556","name":"guldberg_vessels_hires.jpg","image_path":"\/sites\/default\/files\/images\/guldberg_vessels_hires_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/guldberg_vessels_hires_0.jpg","mime":"image\/jpeg","size":151340,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/guldberg_vessels_hires_0.jpg?itok=qcSq_8wy"}}},"media_ids":["71712"],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"}],"keywords":[{"id":"9567","name":"Bob Guldberg"},{"id":"248","name":"IBB"},{"id":"541","name":"Mechanical Engineering"},{"id":"13428","name":"Parker H. Petit Institute for Bioengineering and Bioscience; Pete Petit; Robert Guldberg"},{"id":"11629","name":"Robert Guldberg"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EAbby Robinson\u0026nbsp;\u003Cbr \/\u003E404-385-3364\u003Cbr \/\u003E\u003Cbr \/\u003EJohn Toon\u003Cbr \/\u003E404-894-6986\u003Cbr \/\u003E\u003Cbr \/\u003EResearch News \u0026amp; Publications Office\u0026nbsp;\u003C\/p\u003E","format":"limited_html"}],"email":["abby@innovate.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"71510":{"#nid":"71510","#data":{"type":"external_news","title":"Real Science, Real Impact","body":[{"value":"\u003Cp\u003EBiotech and life sciences flourish as Georgia researchers breed hope in their labs.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27195","created_gmt":"2011-10-18 08:30:44","changed_gmt":"2016-10-08 02:25:09","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","publication":"sustainability planning","field_article_url":"","publication_url":"http:\/\/www.georgiatrend.com\/October-2011\/Real-Science-Real-Impact\/","dateline":{"date":"2011-10-01T00:00:00-04:00","iso_date":"2011-10-01T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"140","name":"Cancer Research"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"150","name":"Physics and Physical Sciences"}],"keywords":[{"id":"11644","name":"Georgia Trend"},{"id":"14774","name":"Real science real impact"},{"id":"168926","name":"sciele"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"70130":{"#nid":"70130","#data":{"type":"news","title":"Transformative NIH Grant Will Support Development of Tissue Regeneration Therapeutics","body":[{"value":"\u003Cp\u003EThe National Institutes of Health (NIH) has awarded nearly $2 million to researchers at the Georgia Institute of Technology and Emory University to develop a new class of therapeutics for treating traumatic injuries and degenerative diseases.\u003C\/p\u003E\u003Cp\u003EThe five-year project focuses on developing biomaterials capable of capturing certain molecules from embryonic stem cells and delivering them to wound sites to enhance tissue regeneration in adults. By applying these unique molecules, clinicians may be able to harness the regenerative power of stem cells while avoiding concerns of tumor formation and immune system compatibility associated with most stem cell transplantation approaches.\u003C\/p\u003E\u003Cp\u003E\u0022Pre-clinical and clinical evidence strongly suggests that the biomolecules produced by stem cells significantly impact tissue regeneration independent of differentiation into functionally competent cells,\u0022 said Todd McDevitt, director of the Stem Cell Engineering Center at Georgia Tech and an associate professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. \u0022We want to find out if the signaling molecules responsible for scarless wound healing and functional tissue restoration during early stages of embryological development can be used with adult wounds to produce successful tissue regeneration without scar formation.\u0022\u003C\/p\u003E\u003Cp\u003EIn addition to McDevitt, Coulter Department associate professor Johnna Temenoff and Woodruff School of Mechanical Engineering professor Robert Guldberg are also investigators on the project.\u003C\/p\u003E\u003Cp\u003ERegenerative medicine seeks to restore normal structure and function to tissues compromised by degenerative diseases and traumatic injuries. The contrast between embryonic and adult wound healing suggests that molecules that facilitate tissue regeneration during embryonic development are distinctly different from those of adult tissues.\u003C\/p\u003E\u003Cp\u003EThis grant includes plans for engineering biomaterials that can efficiently capture morphogens, which are molecules secreted by embryonic stem cells undergoing differentiation. The study will also evaluate the regenerative activity of molecule-filled biomaterials in animal models of dermal wound healing, hind limb ischemia and bone fractures. Examining the effects of the morphogens on a range of animal wound models will increase the likelihood of success and define any limitations of the technology, such as its use for specific tissues or injuries.\u003C\/p\u003E\u003Cp\u003E\u0022Biomaterials have largely been used in an attempt to direct stem cell differentiation or serve as passive cell transplantation vehicles for regenerative medicine and tissue engineering purposes,\u0022 said McDevitt, who is also a Petit Faculty Fellow in the Institute for Bioengineering and Bioscience at Georgia Tech. \u0022The idea of specifically engineering biomaterial properties to capture and deliver complex assemblies of stem cell-derived morphogens without transplanting the cells themselves represents a novel strategy to translate the potency of stem cells into a viable regenerative medicine therapy.\u0022\u003C\/p\u003E\u003Cp\u003EThe award was one of 17 granted this year through the NIH Director\u0027s Transformative Research Projects Program (T-R01), which was created to challenge the status quo with innovative ideas that have the potential to advance fields and speed the translation of research into improved health for the American public.\u003C\/p\u003E\u003Cp\u003EAnother T-R01 grant was awarded to Coulter Department professor Shuming Nie, associate professor May Wang and University of Pennsylvania School of Medicine Thoracic Surgery Research Laboratory director Sunil Singhal. That $7 million, five-year grant will support continuing work by the Emory-Georgia Tech Nanotechnology Center for Personalized and Predictive Oncology team on developing fluorescent nanoparticle probes that hone in on cancer cells and on creating instruments that visualize them for cancer detection during surgery.\u003C\/p\u003E\u003Cp\u003ESince its inception in 2009, the NIH Director\u0027s Award Program has funded a total of 406 high-risk research projects, including 79 T-R01 awards.\u003C\/p\u003E\u003Cp\u003E\u0022The NIH Director\u0027s Award programs reinvigorate the biomedical work force by providing unique opportunities to conduct research that is neither incremental nor conventional,\u0022 said James M. Anderson, director of the Division of Program Coordination, Planning and Strategic Initiatives, who guides the NIH Common Fund\u0027s High-Risk Research program. \u0022The awards are intended to catalyze giant leaps forward for any area of biomedical research, allowing investigators to go in entirely new directions.\u0022\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E Georgia Institute of Technology\u003Cbr \/\u003E 75 Fifth Street, N.W., Suite 314\u003Cbr \/\u003E Atlanta, Georgia 30308 USA\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EMedia Relations Contacts:\u003C\/strong\u003E Abby Robinson (abby@innovate.gatech.edu; 404-385-3364) or John Toon (jtoon@gatech.edu; 404-894-6986)\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EWriter:\u003C\/strong\u003E Abby Robinson\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EThe National Institutes of Health (NIH) has awarded nearly $2 million to researchers at the Georgia Institute of Technology and Emory University to develop a new class of therapeutics for treating traumatic injuries and degenerative diseases.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Transformative NIH grant awarded to Georgia Tech and Emory researchers."}],"uid":"27206","created_gmt":"2011-09-20 00:00:00","changed_gmt":"2016-10-08 03:10:09","author":"Abby Vogel Robinson","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-09-20T00:00:00-04:00","iso_date":"2011-09-20T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"70131":{"id":"70131","type":"image","title":"Todd McDevitt","body":null,"created":"1449177288","gmt_created":"2015-12-03 21:14:48","changed":"1475894616","gmt_changed":"2016-10-08 02:43:36"},"70132":{"id":"70132","type":"image","title":"Todd McDevitt\/Marissa Cooke\/Alyssa Ngangan","body":null,"created":"1449177288","gmt_created":"2015-12-03 21:14:48","changed":"1475894616","gmt_changed":"2016-10-08 02:43:36"},"70133":{"id":"70133","type":"image","title":"Todd McDevitt\/Marissa Cooke\/Alyssa Ngangan","body":null,"created":"1449177288","gmt_created":"2015-12-03 21:14:48","changed":"1475894616","gmt_changed":"2016-10-08 02:43:36"}},"media_ids":["70131","70132","70133"],"related_links":[{"url":"http:\/\/www.bme.gatech.edu\/facultystaff\/faculty_record.php?id=78","title":"Todd McDevitt"},{"url":"http:\/\/www.bme.gatech.edu\/facultystaff\/faculty_record.php?id=84","title":"Johnna Temenoff"},{"url":"http:\/\/www.me.gatech.edu\/faculty\/guldberg.shtml","title":"Robert Guldberg"},{"url":"http:\/\/www.bme.gatech.edu\/","title":"Wallace H. Coulter Department of Biomedical Engineering"},{"url":"http:\/\/www.me.gatech.edu\/","title":"George W. Woodruff School of Mechanical Engineering"}],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"135","name":"Research"}],"keywords":[{"id":"3024","name":"biomaterials"},{"id":"594","name":"college of engineering"},{"id":"14376","name":"Degenerative Diseases"},{"id":"11533","name":"Department of Biomedical Engineering"},{"id":"14370","name":"Johnna Temenoff"},{"id":"14371","name":"morphogen"},{"id":"2076","name":"NIH"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EAbby Robinson\u003C\/strong\u003E\u003Cbr \/\u003EResearch News and Publications\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=avogel6\u0022\u003EContact Abby Robinson\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-3364\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["abby@innovate.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"69191":{"#nid":"69191","#data":{"type":"external_news","title":"New center helps bring medical technology to market","body":[{"value":"\u003Cp\u003EResearchers across Georgia and the Southeast soon will have a new outlet for turning their ideas into reality for medical devices with the launch of the Global Center for Medical Innovation.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27195","created_gmt":"2011-08-05 10:27:59","changed_gmt":"2016-10-08 02:25:03","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","publication_url":"http:\/\/www.ajc.com\/business\/new-center-helps-bring-1068812.html","dateline":{"date":"2011-08-02T00:00:00-04:00","iso_date":"2011-08-02T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"140","name":"Cancer Research"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"150","name":"Physics and Physical Sciences"}],"keywords":[{"id":"13911","name":"New center helps bring medical center to market"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"68790":{"#nid":"68790","#data":{"type":"news","title":"Study Shows H1N1 Microneedle Vaccine Protects Better Than Injection","body":[{"value":"\u003Cp\u003EA vaccine delivered to the skin using a microneedle patch gives better protection against the H1N1 influenza virus than a vaccine delivered through subcutaneous or intramuscular injection, researchers from Emory University and the Georgia Institute of Technology have found. Their research is published online in the \u003Cem\u003EJournal of Infectious Diseases\u003C\/em\u003E.\u003C\/p\u003E\n\u003Cp\u003EMice given a single H1N1 vaccine through the skin using a coated metal microneedle patch as well as mice vaccinated through subcutaneous injection were 100 percent protected against a lethal flu virus challenge six weeks after vaccination. However, when challenged with the H1N1 virus six months later, the injected mice had a 60 percent decrease in antibody production against the virus and extensive lung inflammation. Mice that were vaccinated with microneedles, on the other hand, maintained high levels of protection and antibody production after six months, with no signs of lung inflammation.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022A major goal of influenza vaccine development has been to confer strong immune responses, including immunological memory and cellular immune responses for long-term protection, and to limit virus spread after infection,\u0022 said first author Dimitrios Koutsonanos, MD, post-doctoral fellow of microbiology and immunology at Emory University School of Medicine. \n\u003C\/p\u003E\n\u003Cp\u003EThe research team also included Ioanna Skountzou, MD, PhD, Richard Compans, PhD, Maria del Pilar Martin, PhD, and Joshy Jacob, PhD, from Emory, and Georgia Tech bioengineers Mark Prausnitz, PhD, and Vladimir Zarnitsyn, PhD.\n\u003C\/p\u003E\n\u003Cp\u003EResearchers already have found that intramuscular injection is not the most efficient way to deliver vaccines. The muscles have a low concentration of cells needed to relay immune signals and activate a T-cell response, including dendritic cells, macrophages, and MHC class II-expressing cells. The skin, however, contains a rich network of antigen-presenting cells, including macrophages, Langerhans cells and dermal dendritic cells that activate cytokines and chemokines \u2013 immune signaling cells responsible for initiating an immune response. \n\u003C\/p\u003E\n\u003Cp\u003EThe Emory\/Georgia Tech research team previously reported that delivery of seasonal influenza vaccine through the skin using antigen-coated metal microneedle patches or dissolving microneedles elicited strong immune responses that can confer protection at least equal to conventional intramuscular injections. The team has developed dissolving microneedle technology that could be used in easy-to-administer, painless patches. \n\u003C\/p\u003E\n\u003Cp\u003E\u0022The pandemic H1N1 A\/California\/04\/09 influenza virus continues to be the predominant strain,\u0022 said lead researcher Ioanna Skountzou, MD, PhD, assistant professor of microbiology and immunology at Emory University School of Medicine. \u0022Our research shows that skin-based vaccination, made possible through microneedle technology, may now be a viable and more effective alternative to intramuscular injection for H1N1 flu and other strains as well.\u0022\n\u003C\/p\u003E\n\u003Cp\u003E\u0022Microneedle delivery also offers other logistical advantages that make this method attractive for influenza vaccination, such as inexpensive manufacturing, small size for easy storage and distribution, and simple administration that might enable self-vaccination to increase patient coverage,\u0022 said Prausnitz. \n\u003C\/p\u003E\n\u003Cp\u003E\u003Cem\u003EThis news release was written by Emory University\u003C\/em\u003E.\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EMedia Contacts\u003C\/strong\u003E: Holly Korschun, Emory University (404-727-3990)(\u003Ca href=\u0022mailto:hkorsch@emory.edu\u0022\u003Ehkorsch@emory.edu\u003C\/a\u003E) or John Toon (404-894-6986)(\u003Ca href=\u0022mailto:jtoon@gatech.edu\u0022\u003Ejtoon@gatech.edu\u003C\/a\u003E). \n\u003C\/p\u003E\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EVaccine delivered to the skin using a microneedle patch gives better protection against the H1N1 influenza virus than a vaccine delivered through subcutaneous or intramuscular injection, researchers have found.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Vaccination with microneedles gives better H1N1 influenza protection."}],"uid":"27303","created_gmt":"2011-07-11 00:00:00","changed_gmt":"2016-10-08 03:09:44","author":"John Toon","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-07-11T00:00:00-04:00","iso_date":"2011-07-11T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"68791":{"id":"68791","type":"image","title":"Steel microneedle array","body":null,"created":"1449177201","gmt_created":"2015-12-03 21:13:21","changed":"1475894599","gmt_changed":"2016-10-08 02:43:19"}},"media_ids":["68791"],"related_links":[{"url":"http:\/\/www.chbe.gatech.edu\/","title":"School of Chemical \u0026 Biomolecular Engineering"},{"url":"http:\/\/www.chbe.gatech.edu\/faculty\/prausnitz.php","title":"Mark Prausnitz"}],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"146","name":"Life Sciences and Biology"},{"id":"135","name":"Research"}],"keywords":[{"id":"764","name":"immunization"},{"id":"765","name":"influenza"},{"id":"495","name":"Mark Prausnitz"},{"id":"494","name":"Microneedle"},{"id":"13653","name":"microneedle patch"},{"id":"7360","name":"vaccination"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EJohn Toon\u003C\/strong\u003E\u003Cbr \/\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=jt7\u0022\u003EContact John Toon\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-6986\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["jtoon@gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"68719":{"#nid":"68719","#data":{"type":"news","title":"Unique Gel Capsule Structure Enables Multiple Drug Delivery","body":[{"value":"\u003Cp\u003EResearchers at the Georgia Institute of Technology have designed a multiple-compartment gel capsule that could be used to simultaneously deliver drugs of different types. The researchers used a simple \u0022one-pot\u0022 method to prepare the hydrogel capsules, which measure less than one micron.\u003C\/p\u003E\n\u003Cp\u003EThe capsule\u0027s structure -- hollow except for polymer chains tethered to the interior of the shell -- provides spatially-segregated compartments that make it a good candidate for multi-drug encapsulation and release strategies. The microcapsule could be used to simultaneously deliver distinct drugs by filling the core of the capsule with hydrophilic drugs and trapping hydrophobic drugs within nanoparticles assembled from the polymer chains. \n\u003C\/p\u003E\n\u003Cp\u003E\u0022We have demonstrated that we can make a fairly complex multi-component delivery vehicle using a relatively straightforward and scalable synthesis,\u0022 said L. Andrew Lyon, a professor in the School of Chemistry and Biochemistry at Georgia Tech. \u0022Additional research will need to be conducted to determine how they would best be loaded, delivered and triggered to release the drugs.\u0022\u003C\/p\u003E\n\u003Cp\u003EDetails of the microcapsule synthesis procedure were published online on July 5, 2011 in the journal \u003Cem\u003EMacromolecular Rapid Communications\u003C\/em\u003E. \n\u003C\/p\u003E\n\u003Cp\u003ELyon and Xiaobo Hu, a former visiting scholar at Georgia Tech, created the microcapsules. As a graduate student at the Research Institute of Materials Science at the South China University of Technology, Hu is co-advised by Lyon and Zhen Tong of the South China University of Technology. Funding for this research was provided to Hu by the China Scholarship Council.\n\u003C\/p\u003E\n\u003Cp\u003EThe researchers began the two-step, one-pot synthesis procedure by forming core particles from a temperature-sensitive polymer called poly(N-isopropylacrylamide). To create a dissolvable core, they formed polymer chains from the particles without a cross-linking agent. This resulted in an aggregated collection of polymer chains with temperature-dependent stability.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022The polymer comprising the core particles is known for undergoing chain transfer reactions that add cross-linking points without the presence of a cross-linking agent, so we initiated the polymerization using a redox method with ammonium persulfate and N,N,N\u2019,N\u2019-tetramethylethylenediamine. This ensured those side chain transfer reactions did not occur, which allowed us to create a truly dissolvable core,\u0022 explained Lyon.\u003C\/p\u003E\n\u003Cp\u003EFor the second step in the procedure, Lyon and Hu added a cross-linking agent to a polymer called poly(N-isopropylmethacrylamide) to create a shell around the aggregated polymer chains. The researchers conducted this step under conditions that would allow any core-associated polymer chains that interacted with the shell during synthesis to undergo chain transfer and become grafted to the interior of the shell. \n\u003C\/p\u003E\n\u003Cp\u003ECooling the microcapsule exploited the temperature sensitivities of the polymers. The shell swelled with water and expanded to its stable size, while the free-floating polymer chains in the center of the capsule diffused out of the core, leaving behind an empty space. Any chains that stuck to the shell during its synthesis remained. Because the chains control the interaction between the particles they store and their surroundings, the tethered chains can act as hydrophobic drug carriers.\n\u003C\/p\u003E\n\u003Cp\u003ECompared to delivering a single drug, co-delivery of multiple drugs has several potential advantages, including synergistic effects, suppressed drug resistance and the ability to tune the relative dosage of various drugs. The future optimization of these microcapsules may allow simultaneous delivery of distinct classes of drugs for the treatment of diseases like cancer, which is often treated using combination chemotherapy.\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E\nGeorgia Institute of Technology\u003Cbr \/\u003E\n75 Fifth Street, N.W., Suite 314\u003Cbr \/\u003E\nAtlanta, Georgia  30308  USA\u003C\/strong\u003E\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EMedia Relations Contacts:\u003C\/strong\u003E Abby Robinson (abby@innovate.gatech.edu; 404-385-3364) or John Toon (jtoon@gatech.edu; 404-894-6986)\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EWriter:\u003C\/strong\u003E Abby Robinson\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EChemists have designed a multiple-compartment gel capsule that can simultaneously deliver hydrophilic and hydrophobic drugs. The microcapsules could be used for the treatment of diseases like cancer, which is often treated using combination chemotherapy.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Microcapsule can deliver hydrophobic and hydrophilic drugs together."}],"uid":"27206","created_gmt":"2011-07-06 00:00:00","changed_gmt":"2016-10-08 03:09:44","author":"Abby Vogel Robinson","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-07-06T00:00:00-04:00","iso_date":"2011-07-06T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"68720":{"id":"68720","type":"image","title":"Microcapsule synthesis schematic","body":null,"created":"1449177201","gmt_created":"2015-12-03 21:13:21","changed":"1475894597","gmt_changed":"2016-10-08 02:43:17"},"68721":{"id":"68721","type":"image","title":"3D AFM images of microcapsules","body":null,"created":"1449177201","gmt_created":"2015-12-03 21:13:21","changed":"1475894597","gmt_changed":"2016-10-08 02:43:17"},"68722":{"id":"68722","type":"image","title":"AFM images of microcapsules","body":null,"created":"1449177201","gmt_created":"2015-12-03 21:13:21","changed":"1475894597","gmt_changed":"2016-10-08 02:43:17"}},"media_ids":["68720","68721","68722"],"related_links":[{"url":"http:\/\/dx.doi.org\/10.1002\/marc.201100338","title":"Macromolecular Rapid Communications paper"},{"url":"http:\/\/www.chemistry.gatech.edu\/faculty\/Lyon\/","title":"Andrew Lyon"},{"url":"http:\/\/www.chemistry.gatech.edu\/","title":"School of Chemistry and Biochemistry"}],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"135","name":"Research"}],"keywords":[{"id":"4912","name":"Andrew Lyon"},{"id":"4896","name":"College of Sciences"},{"id":"3346","name":"drug delivery"},{"id":"13603","name":"Drug Delivery Systems"},{"id":"13604","name":"drug delivery vehicle"},{"id":"7306","name":"hydrophilic"},{"id":"13608","name":"hydrophilic drug"},{"id":"7305","name":"hydrophobic"},{"id":"13607","name":"hydrophobic drug"},{"id":"13605","name":"microcapsule"},{"id":"13606","name":"Multi Drug"},{"id":"7031","name":"pharmaceutical"},{"id":"166928","name":"School of Chemistry and Biochemistry"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EAbby Robinson\u003C\/strong\u003E\u003Cbr \/\u003EResearch News and Publications\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=avogel6\u0022\u003EContact Abby Robinson\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-3364\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["abby@innovate.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"68642":{"#nid":"68642","#data":{"type":"external_news","title":"America\u0027s Top States for Business - Special Report - CNBC","body":[{"value":"\u003Cp\u003EGeorgia Ranked #4 in America\u0027s Best States for Business - CNBC\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27195","created_gmt":"2011-06-29 11:31:13","changed_gmt":"2016-10-08 02:24:59","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","publication_url":"http:\/\/www.cnbc.com\/id\/41665883\/","dateline":{"date":"2011-06-28T00:00:00-04:00","iso_date":"2011-06-28T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"139","name":"Business"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"150","name":"Physics and Physical Sciences"}],"keywords":[{"id":"13568","name":"America\u0027s best states for business"},{"id":"13567","name":"Georgia Ranked Number 4"},{"id":"13566","name":"IBB Industry News"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"68536":{"#nid":"68536","#data":{"type":"news","title":"Obama Taps Georgia Tech President for National Manufacturing Steering Committee","body":[{"value":"\u003Cp\u003EPresident Barack Obama today named Georgia Tech President G. P. \u201cBud\u201d Peterson to the Advanced Manufacturing Partnership steering committee. The partnership will bring together industry, universities and the federal government to identify and invest in the key emerging technologies, such as information technology, biotechnology and nanotechnology. The national initiative is designed to help U.S. manufacturers improve cost, quality and speed of production in order to remain globally competitive.\u003C\/p\u003E\u003Cp\u003E\u201cWe applaud this initiative, and Georgia Tech is honored to collaborate to identify ways to strengthen the manufacturing sector to help create jobs in Georgia and across the United States,\u201d said Peterson, who also serves as a member of the Secretary of Commerce\u0027s National Advisory Council on Innovation and Entrepreneurship.\u003C\/p\u003E\u003Cp\u003EThe steering committee will guide the efforts of industry leaders, federal agency heads and university presidents, and will partner universities with industry and government agencies to develop new research and education agendas related to advanced manufacturing. \u003C\/p\u003E\u003Cp\u003EThe president also announced a new National Robotics Initiative as part of the advanced manufacturing and technology focus. Henrik Christensen, KUKA Chair of Robotics for Georgia Tech, serves as an academic and research leader on the National Robotics Initiative.\u003C\/p\u003E\u003Cp\u003EAccording to Christensen, this is a critical time for the U.S. While the last 25 years saw tremendous progress due to the Internet, the next game-changing revolution will be robotics.\u003C\/p\u003E\u003Cp\u003E\u201cRobotics technology addresses a number of our nation\u2019s most critical needs, including reinvigorating the U.S. manufacturing base, protecting our citizens and soldiers, caring for our aging population, preserving our environment, and reducing our dependence on foreign oil,\u201d Christensen said. \u201cThrough the National Robotics Initiative, the United States can regain our leadership position from Europe, Japan and South Korea, both in terms of basic research and in terms of the application of the technology to secure future growth. As home to one of the nation\u2019s top robotics programs, Georgia Tech is an enthusiastic member of this strategic effort.\u201d\u003C\/p\u003E\u003Cp\u003EThe Advanced Manufacturing Partnership will commit to form a multiuniversity, collaborative framework for the sharing of educational materials and best practices relating to advanced manufacturing and its linkage to the innovation.\u003C\/p\u003E\u003Cp\u003ESusan Hockfield, president of the Massachusetts Institute of Technology and Andrew Liveries of Dow Chemical are chairing the Advanced Manufacturing Partnership steering committee.\u0026nbsp; In addition to Peterson, other committee members include University of California at Berkley Chancellor Robert Birgeneau, University of Michigan President Mary Sue Coleman, Stanford President John Hennessy and Carnegie Mellon President Jared Cohon.\u003C\/p\u003E\u003Cp\u003E\u201cMany of our challenges can be solved through innovation and fostering an entrepreneurial environment, as well as collaboration between industry, education and government to create a healthy economic environment and an educated workforce,\u201d Peterson said. \u201cThis collaborative effort will facilitate job creation and global competitiveness and is a component of Georgia Tech\u2019s strategic plan.\u201d\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"College of Computing Professor Leads National Robotics Roadmap"}],"field_summary":[{"value":"\u003Cp\u003EHenrik Christensen (\u003Cem\u003EInteractive Computing\u003C\/em\u003E), \nKUKA Chair of Robotics for Georgia Tech, to serve as an academic and \nresearch leader on a new National Robotics Initiative announced by President Obama today. \u003Cem\u003ESource: GT Communications \u0026amp; Marketing\u003C\/em\u003E\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":"","uid":"27154","created_gmt":"2011-06-24 15:34:09","changed_gmt":"2016-10-08 03:09:37","author":"Louise Russo","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-06-24T00:00:00-04:00","iso_date":"2011-06-24T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"47223","name":"College of Computing"}],"categories":[],"keywords":[{"id":"13503","name":"Advanced Manufactuing"},{"id":"13504","name":"Advanced Manufacturing Partnership steering committee"},{"id":"2675","name":"economic"},{"id":"11890","name":"henrik christensen"},{"id":"215","name":"manufacturing"},{"id":"13502","name":"President G.P."},{"id":"769","name":"President Obama"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"67771":{"#nid":"67771","#data":{"type":"external_news","title":"Economic forecast is promising","body":[{"value":"\u003Cp\u003EGiven the continued moribund housing and job markets, it may seem hard to believe, but the economy has been in recovery mode for two full years since the trough of the \u201cgreat recession.\u201d\u0026nbsp;\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27195","created_gmt":"2011-06-20 14:43:44","changed_gmt":"2016-10-08 02:24:54","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","publication_url":"http:\/\/www.ajc.com\/business\/economic-forecast-is-promising-980486.html","dateline":{"date":"2011-06-18T00:00:00-04:00","iso_date":"2011-06-18T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"140","name":"Cancer Research"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"}],"keywords":[{"id":"13449","name":"economic forecast is promising"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"66415":{"#nid":"66415","#data":{"type":"news","title":"Ga. Tech Generates Highest Economic Impact among University System Institutions","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003E\u003C\/strong\u003EA newly released report indicates\nthat the Georgia Institute of Technology made a $2.15 billion economic impact during\nfiscal year 2010, the highest of any institution in the University System of\nGeorgia (USG). The Selig Center for Economic Growth in the University of\nGeorgia\u2019s Terry College of Business also found that Georgia Tech generated\n18,127 full- and part-time jobs. \u003C\/p\u003E\n\n\u003Cp\u003EThe annual study showed that with a\n$12.6 billion economic impact on the state\u2019s economy in FY2010, Georgia\u2019s\npublic university system remains a powerful economic engine for the state, generating\n130,738 full- and part-time jobs statewide during the same time period.\u003C\/p\u003E\n\n\u003Cp\u003EThe eight\ninstitutions of the University System located in the metro Atlanta area\naccounted for $5.8 billion of the USG\u2019s $12.6 billion total. Georgia Tech,\nGeorgia State University, Clayton State University, Kennesaw State University,\nSouthern Polytechnic State University, Georgia Gwinnett College, Atlanta\nMetropolitan College and Georgia Perimeter College also produced 53,658 jobs.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"Institute also produces 18,127 full- and part-time jobs"}],"field_summary":[{"value":"\u003Cp\u003EA newly released report indicates\nthat the Georgia Institute of Technology made a $2.15 billion economic impact during\nfiscal year 2010, the highest of any institution in the University System of\nGeorgia (USG).\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"A newly released report indicates that the Georgia Institute of Technology made a $2.15 billion economic impact during fiscal year 2010."}],"uid":"27281","created_gmt":"2011-06-07 16:00:15","changed_gmt":"2016-10-08 03:08:49","author":"Lisa Grovenstein","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-06-07T00:00:00-04:00","iso_date":"2011-06-07T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"62801":{"id":"62801","type":"image","title":"Tech Tower Web Feature","body":null,"created":"1449176394","gmt_created":"2015-12-03 20:59:54","changed":"1475894547","gmt_changed":"2016-10-08 02:42:27","alt":"Tech Tower Web Feature","file":{"fid":"191672","name":"Tech_Tower_WebFeature.jpg","image_path":"\/sites\/default\/files\/images\/Tech_Tower_WebFeature_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/Tech_Tower_WebFeature_0.jpg","mime":"image\/jpeg","size":149983,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/Tech_Tower_WebFeature_0.jpg?itok=jncbZNG2"}}},"media_ids":["62801"],"related_links":[{"url":"http:\/\/www.icapp.org\/pubs\/usg_impact_fy2010.pdf","title":"2011 USG Economic Impact Study"}],"groups":[{"id":"1317","name":"News Briefs"}],"categories":[{"id":"131","name":"Economic Development and Policy"}],"keywords":[{"id":"13344","name":"2011 economic impact"},{"id":"1033","name":"Economic Impact"},{"id":"726","name":"University System of Georgia"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003ELisa Grovenstein, 404-894-8835\u003C\/p\u003E","format":"limited_html"}],"email":["lisa.grovenstein@comm.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"66467":{"#nid":"66467","#data":{"type":"external_news","title":"Research dollars pave way for jobs","body":[{"value":"\u003Cp\u003ETwo of the South\u2019s most prominent native sons \u2014 Ben Bernanke and Newt Gingrich \u2014 \nagree it is important. President Barack Obama calls it \u201cessential to our \nprogress.\u201d What issue can possibly make Republican, Democratic and financial \nleaders sing kumbaya in the age of hyper-partisanship?\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27349","created_gmt":"2011-06-13 09:25:44","changed_gmt":"2016-10-08 02:24:32","author":"Floyd Wood","boilerplate_text":"","field_publication":"","publication":"big tech","field_article_url":"","publication_url":"http:\/\/www.ajc.com\/opinion\/research-dollars-pave-way-969115.html","dateline":{"date":"2011-06-06T00:00:00-04:00","iso_date":"2011-06-06T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"134","name":"Student and Faculty"}],"keywords":[{"id":"248","name":"IBB"},{"id":"13374","name":"IBB Industry"},{"id":"12693","name":"Industry Partners"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"66127":{"#nid":"66127","#data":{"type":"news","title":"Georgia Tech Launching New Accelerator Program","body":"","field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EGeorgia Tech is launching a four-month accelerator program twice a year to back anywhere from 12-20 startups, beginning this August. Merrick Furst (\u003Cem\u003EComputer Science\u003C\/em\u003E) is helping to lead the effort. \u003Cem\u003ESource: TechJournal South\u003C\/em\u003E\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":"","uid":"27166","created_gmt":"2011-05-11 12:51:38","changed_gmt":"2016-10-08 03:08:41","author":"Juliet Helms","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-05-11T00:00:00-04:00","iso_date":"2011-05-11T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/www.techjournalsouth.com\/2011\/05\/georgia-tech-launching-new-accelerator-program\/","title":"http:\/\/www.techjournalsouth.com\/2011\/05\/georgia-tech-launching-new-accelerator-program\/"}],"groups":[{"id":"47223","name":"College of Computing"}],"categories":[],"keywords":[{"id":"13127","name":"accelerator program"},{"id":"167834","name":"start up"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"66185":{"#nid":"66185","#data":{"type":"external_news","title":"ACEBB Seminar - Michael Goodisman","body":[{"value":"\u003Cp\u003EDownload a \u003Cstrong\u003Epodcast\u003C\/strong\u003E of Dr Michael Goodisman presenting at the first ACEBB seminar of 2011.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27195","created_gmt":"2011-05-13 13:42:32","changed_gmt":"2016-10-08 02:24:30","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","publication":"The Environment Institute","field_article_url":"","publication_url":"http:\/\/environmentinstitute.wordpress.com\/2011\/05\/10\/acebb-seminar-dr-michael-goodisman\/","dateline":{"date":"2011-05-10T00:00:00-04:00","iso_date":"2011-05-10T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"}],"keywords":[{"id":"13157","name":"ACEBB Seminar \u2013 Dr. Michael Goodisman"},{"id":"11811","name":"Michael Goodisman"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"66052":{"#nid":"66052","#data":{"type":"news","title":"Georgia Tech Announces New Programs to Foster Entrepreneurship and Innovation","body":[{"value":"\u003Cp\u003EAs part of an ongoing effort to foster innovation and entrepreneurship within its campus community, the Georgia Institute of Technology has announced the creation of three new programs that will complement several well-established initiatives.\u003C\/p\u003E\u003Cp\u003EThe new programs stem from the findings of an innovation task force, co-chaired by Associate Vice President for Research Ravi Bellamkonda and College of Computing Professor Merrick Furst, that was created to support the strategic plan. The task force recommended a number of transformational changes in the Institute\u2019s approach to innovation, including new or expanded programs designed to provide both education and resources to campus innovators.\u003C\/p\u003E\u003Cp\u003E\u201cInnovation is one of the Institute\u2019s primary strategic goals, so it\u2019s essential that we provide the Tech community with the support they need to develop and ultimately commercialize their research and ideas,\u201d said Stephen E. Cross, executive vice president for research.\u0026nbsp; \u003C\/p\u003E\u003Cp\u003EThe new initiatives include:\u003C\/p\u003E\u003Cul\u003E\u003Cli\u003E\u003Cstrong\u003EGeorgia Tech Integrated Program for Startups, GT:IPS:\u003C\/strong\u003E GT:IPS combines a streamlined licensing program with organized support for faculty and student inventor-entrepreneurs. The program consists of two components: GT:IPS Facilitation and the GT:IPS License. GT:IPS Facilitation is a graduated program of support, information and education for new company founders, while the GT:IPS License offers the same terms to all Georgia Tech startups in the same field and provides the startup with transparency into the Georgia Tech Research Corporation\u2019s (GTRC) licensing processes. This program will accelerate the formation of robust Georgia Tech spin out companies and broader participation in entrepreneurship among faculty and students.\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003EA new program designed for early stage for-profit, not-for-profit and policy startups\u003C\/strong\u003E that are both internal and external to Georgia Tech will be officially announced soon. Through a competitive application process, the program will offer 12 to 20 startups the opportunity to tap into Georgia Tech\u2019s entrepreneurial expertise and funding support provided through Georgia Tech\u2019s Edison fund and an investment fund managed through Imlay Investments. The pilot program will be co-directed by Merrick Furst and Nina Sawczuk, general manager of the Advanced Technology Development Center. Information on the application process and opportunities to contribute to the investment funds will be available within the next few weeks.\u0026nbsp;\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003EBio-impact Commercialization Team (BCT):\u003C\/strong\u003E The BCT is a focused, institutional commitment to translational research in biomedicine. A team with expertise in the bio-medical device space will work closely with faculty members and the venture capital community to facilitate translational research and commercialization. The BCT will focus specifically on translational research and development projects funded by the Wallace Coulter Foundation. This team is part of a larger effort to unify work at Tech and various health care strategic partners.\u003C\/li\u003E\u003C\/ul\u003E\u003Cp\u003EThe new programs will complement the following existing initiatives at Tech:\u003C\/p\u003E\u003Cul\u003E\u003Cli\u003E\u003Cstrong\u003EInVenture Prize:\u003C\/strong\u003E The InVenture Prize is an innovation competition where Georgia Tech undergraduate teams create inventions that are judged by a panel of experts. The competition was broadcast live in March 2011 with seven finalist teams competing for more than $30,000 in cash prizes, patent filings funded by GTRC and a \u201cPeople\u2019s Choice\u201d award, sponsored by NCR Corporation.\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003ETI:GER:\u003C\/strong\u003E The award-winning TI:GER Program is a partnership between Georgia Tech and Emory University School of Law that brings together PhD, MBA and law students to learn about the challenges of commercializing innovative technologies. As it approaches its 10th anniversary in 2012, TI:GER is now expanding to global entrepreneurship and has become an established part of the entrepreneurial education of graduate students on both campuses.\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003EUniversity-Industry Demonstration Partnership (UIDP):\u003C\/strong\u003E The UIDP is an activity of the National Academies that works to demonstrate innovative approaches to research engagement and to improve relationships with private industry for research and commercialization of inventions. Associate Vice President for Research Jilda Garton serves as the president of the UIDP.\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003EGeorgia Tech Fund for Innovation in Research and Education (GT FIRE):\u003C\/strong\u003E GT FIRE aims to facilitate planning for large extramural proposals \u2014 those that are of strategic value to the Institute and have more than $500,000 in direct costs per year \u2014 and to provide support for feasibility studies of transformative ideas in research and\/or education. Faculty submitted 42 transformative proposals this spring, of which three research-related ideas and four education-related ideas were selected for funding.\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003ETechnology and Law:\u003C\/strong\u003E Georgia Tech is engaged with the Georgia State University College of Law\u2019s Center for Law, Health and Society and its Intellectual Property Advisory Board in the analysis of policy at the intersection of law and technology, particularly in emerging healthcare digital technologies. Ivan Allen College Associate Professor Roberta M. Berry leads the collaboration for Georgia Tech.\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003EGeorgia VentureLab:\u003C\/strong\u003E This program provides comprehensive assistance to faculty members, research staff members and graduate students who want to form startup companies to commercialize the technology innovations they have developed. As a one-stop center for technology commercialization, VentureLab provides a clear pathway from laboratory innovation to the commercial market. VentureLab specialists help transform innovations into early-stage companies by assisting in business plan development, connecting the innovators with experienced entrepreneurs, locating sources of early-stage financing and preparing the new companies for the business world. The program has fostered, on average, one new spin out each month over the last three years.\u003C\/li\u003E\u003C\/ul\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EAs part of an ongoing effort to foster innovation and entrepreneurship within its campus community, the Georgia Institute of Technology has announced the creation of three new programs that will complement several well-established initiatives. Merrick Furst (\u003Cem\u003EComputer Science\u003C\/em\u003E) to co-direct program for early-stage startups. \u003Cem\u003ESource: GT Communications \u0026amp; Marketing\u003C\/em\u003E\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":"","uid":"27154","created_gmt":"2011-05-09 16:25:38","changed_gmt":"2016-10-08 03:08:41","author":"Louise Russo","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-05-09T00:00:00-04:00","iso_date":"2011-05-09T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"47223","name":"College of Computing"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EGeorgia Tech Media Relations\u003C\/strong\u003E\u003Cbr \/\u003ELaura Diamond\u003Cbr \/\u003E\u003Ca href=\u0022mailto:laura.diamond@comm.gatech.edu\u0022\u003Elaura.diamond@comm.gatech.edu\u003C\/a\u003E\u003Cbr \/\u003E404-894-6016\u003Cbr \/\u003EJason Maderer\u003Cbr \/\u003E\u003Ca href=\u0022mailto:maderer@gatech.edu\u0022\u003Emaderer@gatech.edu\u003C\/a\u003E\u003Cbr \/\u003E404-660-2926\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"66184":{"#nid":"66184","#data":{"type":"external_news","title":"Four GRA VentureLab companies graduate from ATDC","body":[{"value":"\u003Cp\u003EFour GRA VentureLab companies are among the nine startups that will be featured as graduates of the Advanced Technology Development Center, Georgia Tech\u2019s business incubator.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27195","created_gmt":"2011-05-13 13:40:04","changed_gmt":"2016-10-08 02:24:30","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","publication":"sadakat","field_article_url":"","publication_url":"http:\/\/georgiaresearchalliance.wordpress.com\/2011\/05\/09\/four-gra-venturelab-companies-graduate-from-atdc\/","dateline":{"date":"2011-05-09T00:00:00-04:00","iso_date":"2011-05-09T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"}],"keywords":[{"id":"13156","name":"Four GRA VentureLab companies graduate from ATDC"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"66014":{"#nid":"66014","#data":{"type":"news","title":"Georgia Tech Announces New Programs to Foster Entrepreneurship and Innovation","body":[{"value":"\u003Cp\u003EAs part of an ongoing effort to foster innovation and entrepreneurship within its campus community, the Georgia Institute of Technology has announced the creation of three new programs that will complement several well-established initiatives.\u0026nbsp; \u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe new programs stem from the findings of an innovation task force, co-chaired by Associate Vice President for Research Ravi Bellamkonda and College of Computing Professor Merrick Furst, that was created to support the strategic plan. The task force recommended a number of transformational changes in the Institute\u2019s approach to innovation, including new or expanded programs designed to provide both education and resources to campus innovators. \u003C\/p\u003E\u003Cp\u003E\u201cInnovation is one of the Institute\u2019s primary strategic goals, so it\u2019s essential that we provide the Tech community with the support they need to develop and ultimately commercialize their research and ideas,\u201d said Stephen E. Cross, executive vice president for research. \u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe new initiatives include:\u003C\/p\u003E\u003Cul\u003E\u003Cli\u003E\u003Cstrong\u003EGeorgia Tech Integrated Program for Startups, GT:IPS:\u003C\/strong\u003E\u0026nbsp; GT:IPS combines a streamlined licensing program with organized support for faculty and student inventor-entrepreneurs. The program consists of two components: GT:IPS Facilitation and the GT:IPS License. GT:IPS Facilitation is a graduated program of support, information and education for new company founders, while the GT:IPS License offers the same terms to all Georgia Tech startups in the same field and provides the startup with transparency into the Georgia Tech Research Corporation\u2019s (GTRC) licensing processes. This program will accelerate the formation of robust Georgia Tech spin out companies and broader participation in entrepreneurship among faculty and students.\u003C\/li\u003E\u003C\/ul\u003E\u003Cul\u003E\u003Cli\u003E\u003Cstrong\u003EA new program designed for early stage for-profit, not-for-profit and policy startups\u003C\/strong\u003E that are both internal and external to Georgia Tech will be officially announced soon. Through a competitive application process, the program will offer 12 to 20 startups the opportunity to tap into Georgia Tech\u2019s entrepreneurial expertise and funding support provided through Georgia Tech\u2019s Edison fund and an investment fund managed through Imlay Investments. The pilot program will be co-directed by Merrick Furst and Nina Sawczuk, general manager of the Advanced Technology Development Center. Information on the application process and opportunities to contribute to the investment funds will be available within the next few weeks. \u003C\/li\u003E\u003C\/ul\u003E\u003Cul\u003E\u003Cli\u003E\u003Cstrong\u003EBio-impact Commercialization Team (BCT):\u003C\/strong\u003E The BCT is a focused, institutional commitment to translational research in biomedicine. A team with expertise in the bio-medical device space will work closely with faculty members and the venture capital community to facilitate translational research and commercialization. The BCT will focus specifically on translational research and development projects funded by the Wallace Coulter Foundation. This team is part of a larger effort to unify work at Tech and various health care strategic partners.\u003C\/li\u003E\u003C\/ul\u003E\u003Cp\u003EThe new programs will complement the following existing initiatives at Tech: \u0026nbsp;\u003C\/p\u003E\u003Cul\u003E\u003Cli\u003E\u003Cstrong\u003EInVenture Prize:\u003C\/strong\u003E The \u003Ca href=\u0022http:\/\/www.inventureprize.gatech.edu\u0022\u003EInVenture Prize\u003C\/a\u003E is an innovation competition where Georgia Tech undergraduate teams create inventions that are judged by a panel of experts. The competition was broadcast live in March 2011 with seven finalist teams competing for more than $30,000 in cash prizes, patent filings funded by GTRC and a \u201cPeople\u2019s Choice\u201d award, sponsored by NCR Corporation.\u003C\/li\u003E\u003C\/ul\u003E\u003Cul\u003E\u003Cli\u003E\u003Cstrong\u003ETI:GER:\u003C\/strong\u003E The award-winning \u003Ca href=\u0022http:\/\/tiger.gatech.edu\u0022\u003ETI:GER Program\u003C\/a\u003E is a partnership between Georgia Tech and Emory University School of Law that brings together PhD, MBA and law students to learn about the challenges of commercializing innovative technologies. As it approaches its 10th anniversary in 2012, TI:GER is now expanding to global entrepreneurship and has become an established part of the entrepreneurial education of graduate students on both campuses.\u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003EBusiness Plan\nCompetition \u003C\/strong\u003E(\u003Ca href=\u0022http:\/\/mgt.gatech.edu\/fac_research\/centers_initiatives\/bpc\/bpc_back.html\u0022\u003EBPC\u003C\/a\u003E):\nOperated by the College of Management and the Institute for Leadership and\nEntrepreneurship (ILE), this annual competition marks its\n11th year fostering entrepreneurship among Georgia Tech students and recent\nalumni. Since\nits inception, more than 650 participants have received approximately $570,000\nin cash and services. Each year several teams\u0026nbsp;launch companies to take\ntheir product concepts to the market. Eight of the past winning teams have been\naccepted into ATDC.\u0026nbsp; \u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003E\u0026nbsp;Ideas to SERVE\n(I2S)\u003C\/strong\u003E: \u003Ca href=\u0022http:\/\/www.ile.gatech.edu\/i2s\/index.html\u0022\u003EI2S\u003C\/a\u003E is a competition of\nideas where creativity, imagination and the use of technology are applied\ninnovatively to solve community and social issues and sustain the\nenvironment.\u0026nbsp; Started as a specialty\ntrack of the BPC in 2009, I2S has quickly grown into a separate event\ncontributing to Georgia Tech\u2019s portfolio of programs fostering entrepreneurship.\nThe program is open to Georgia Tech students and recent alumni.\u003C\/li\u003E\u003C\/ul\u003E\n\n\n\n\n\n\u003Cul\u003E\u003Cli\u003E\u003Cstrong\u003EUniversity-Industry Demonstration Partnership (UIDP):\u003C\/strong\u003E The \u003Ca href=\u0022http:\/\/sites.nationalacademies.org\/PGA\/uidp\/index.htm\u0022\u003EUIDP\u003C\/a\u003E is an activity of the National Academies that works to demonstrate innovative approaches to research engagement and to improve relationships with private industry for research and commercialization of inventions. Associate Vice President for Research Jilda Garton serves as the president of the UIDP.\u003C\/li\u003E\u003C\/ul\u003E\u003Cul\u003E\u003Cli\u003E\u003Cstrong\u003EGeorgia Tech Fund for Innovation in Research and Education (GT FIRE):\u003C\/strong\u003E GT FIRE aims to facilitate planning for large extramural proposals \u2014 those that are of strategic value to the Institute and have more than $500,000 in direct costs per year \u2014 and to provide support for feasibility studies of transformative ideas in research and\/or education. Faculty submitted 42 transformative proposals this spring, of which three research-related ideas and four education-related ideas were selected for funding.\u003C\/li\u003E\u003C\/ul\u003E\u003Cul\u003E\u003Cli\u003E\u003Cstrong\u003ETechnology and Law:\u003C\/strong\u003E Georgia Tech is engaged with the Georgia State University College of Law\u2019s Center for Law, Health and Society and its Intellectual Property Advisory Board in the analysis of policy at the intersection of law and technology, particularly in emerging healthcare digital technologies. Ivan Allen College Associate Professor Roberta M. Berry leads the collaboration for Georgia Tech.\u003C\/li\u003E\u003C\/ul\u003E\u003Cul\u003E\u003Cli\u003E\u003Cstrong\u003EGeorgia Tech VentureLab:\u003C\/strong\u003E This program provides comprehensive assistance to faculty members, research staff members and graduate students who want to form startup companies to commercialize the technology innovations they have developed. As a one-stop center for technology commercialization, \u003Ca href=\u0022http:\/\/www.gtventurelab.com\/\u0022\u003EVentureLab\u003C\/a\u003E provides a clear pathway from laboratory innovation to the commercial market. VentureLab specialists help transform innovations into early-stage companies by assisting in business plan development, connecting the innovators with experienced entrepreneurs, locating sources of early-stage financing and preparing the new companies for the business world. The program has fostered, on average, one new spin out each month over the last three years. \u003C\/li\u003E\u003Cli\u003E\u003Cstrong\u003EGT Edison Fund:\u003C\/strong\u003E Making small investments into very early-stage technology startups that have a strong connection to Georgia Tech, this fund makes use of charitable contributions targeted by alumni and friends of the Institute.\u003C\/li\u003E\u003C\/ul\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EAs part of an ongoing effort to foster innovation and entrepreneurship within its campus community, the Georgia Institute of Technology has announced the creation of three new programs that will complement several well-established initiatives.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"The Institute is creating three new programs that will complement several well-established initiatives."}],"uid":"27445","created_gmt":"2011-05-09 08:59:39","changed_gmt":"2016-10-08 03:08:41","author":"Amelia Pavlik","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-05-09T00:00:00-04:00","iso_date":"2011-05-09T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"60236":{"id":"60236","type":"image","title":"Tech Tower","body":null,"created":"1449176253","gmt_created":"2015-12-03 20:57:33","changed":"1475894523","gmt_changed":"2016-10-08 02:42:03","alt":"Tech Tower","file":{"fid":"191079","name":"tac81885.jpg","image_path":"\/sites\/default\/files\/images\/tac81885_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tac81885_0.jpg","mime":"image\/jpeg","size":1761682,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tac81885_0.jpg?itok=EWM3UfV7"}}},"media_ids":["60236"],"related_links":[{"url":"http:\/\/www.evpr.gatech.edu\/","title":"Georgia Tech Executive Vice President for Research"},{"url":"http:\/\/innovate.gatech.edu\/","title":"Enterprise Innovation Institute"}],"groups":[{"id":"1183","name":"Home"}],"categories":[{"id":"129","name":"Institute and Campus"}],"keywords":[{"id":"13071","name":"Bio-impact Commercialization Team"},{"id":"13074","name":"Georgia VentureLab"},{"id":"12629","name":"GT FIRE"},{"id":"13070","name":"GT:IPS"},{"id":"341","name":"innovation"},{"id":"7764","name":"InVenture Prize"},{"id":"13073","name":"Technology and Law"},{"id":"8457","name":"TI:GER"},{"id":"13072","name":"University-Industry Demonstration Partnership"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EGeorgia Tech Media Relations\u003C\/strong\u003E\u003Cbr \/\u003ELaura Diamond\u003Cbr \/\u003E\u003Ca href=\u0022mailto:laura.diamond@comm.gatech.edu\u0022\u003Elaura.diamond@comm.gatech.edu\u003C\/a\u003E\u003Cbr \/\u003E404-894-6016\u003Cbr \/\u003EJason Maderer\u003Cbr \/\u003E\u003Ca href=\u0022mailto:maderer@gatech.edu\u0022\u003Emaderer@gatech.edu\u003C\/a\u003E\u003Cbr \/\u003E404-660-2926\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"66183":{"#nid":"66183","#data":{"type":"external_news","title":"ATL gets new tech economic developer","body":[{"value":"\u003Cp\u003ELarry\u0026nbsp;Williams has joined the Metro Atlanta Chambe\u003Ca href=\u0022http:\/\/www.metroatlantachamber.com\/Default.aspx?AspxAutoDetectCookieSupport=1\u0022\u003Er\u003C\/a\u003E as vice president of technology industry economic development. He has experience in business development, company relocation project management and closing deals.\u003C\/p\u003E\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\n\u003Cp\u003E\u003Cbr \/\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27195","created_gmt":"2011-05-13 13:21:45","changed_gmt":"2016-10-08 02:24:30","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","publication":"breakthrough cases","field_article_url":"","publication_url":"http:\/\/www.bizjournals.com\/atlanta\/blog\/atlantech\/2011\/05\/williams.html?ed=2011-05-05\u0026s=article_du\u0026ana=e_du_pap","dateline":{"date":"2011-05-05T00:00:00-04:00","iso_date":"2011-05-05T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"139","name":"Business"},{"id":"140","name":"Cancer Research"},{"id":"145","name":"Engineering"},{"id":"149","name":"Nanotechnology and Nanoscience"}],"keywords":[{"id":"13154","name":"ATL gets new tech economic developer"},{"id":"13155","name":"Larry Williams"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"65611":{"#nid":"65611","#data":{"type":"external_news","title":"Study: Atlanta a hotbed for entrepreneurship","body":[{"value":"\u003Cp\u003EGeorgia led the nation in new business startups in 2010, while Atlanta tied for the second-most among the 15 biggest metro areas, according to the Kauffman Index of Entrepreneurial Activity, produced by the Kansas City-based Kauffman Foundation.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27195","created_gmt":"2011-04-18 13:02:25","changed_gmt":"2016-10-08 02:24:27","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","publication_url":"http:\/\/www.ajc.com\/business\/study-atlanta-a-hotbed-864013.html","dateline":{"date":"2011-03-07T00:00:00-05:00","iso_date":"2011-03-07T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"140","name":"Cancer Research"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"150","name":"Physics and Physical Sciences"}],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"64054":{"#nid":"64054","#data":{"type":"news","title":"Atlanta Company Pioneers Medical Devices with Georgia Tech Help","body":[{"value":"\u003Cp\u003ECardioMEMS, a graduate of Georgia Tech\u0027s ATDC startup accelerator, is a rising star in the medical device industry. Pioneering a new class of monitoring devices for heart patients, the company completed a successful clinical trial in May 2010 for its second product, which resulted in a $60 million equity investment and purchase option from St. Jude Medical Inc., a large medical device company based in St. Paul, Minn.\u003C\/p\u003E\n\u003Cp\u003EThat investment earned the company a 2011 \u0022Deal of the Year\u0022 award from Georgia Bio, a nonprofit association that represents Georgia\u0027s pharmaceutical, biotech and medical device community.\n\u003C\/p\u003E\n\u003Cp\u003ECardioMEMS, which has more than 65 employees, grew out of Georgia Tech research. The company\u0027s products combine wireless communications technology with microelectromechanical systems (MEMS) fabrication, providing doctors with more information while making monitoring less invasive for patients. \n\u003C\/p\u003E\n\u003Cp\u003EMEMS uses micro-machining fabrication to build electrical and mechanical systems at the micron scale -- one-millionth of a meter. Using technology originally developed for the integrated circuit industry, MEMS is an attractive platform for medical devices because mechanical, sensing and computational functions can be placed on a single chip.\n\u003C\/p\u003E\n\u003Cp\u003ECardioMEMS began marketing its first product in 2006: the EndoSure sensor, which measures blood pressure inside a repaired abdominal aortic aneurysm. Implanted along with a stent graft during endovascular repair, this tiny sensor may allow doctors to monitor post-surgery patients more effectively than the CT scans that had previously been used. The EndoSure sensor is also less expensive and more convenient. \n\u003C\/p\u003E\n\u003Cp\u003ENow the company\u0027s second product, a sensor that measures intracardiac pressure in people who suffer from congestive heart failure, is moving closer to FDA approval.\n\u003C\/p\u003E\n\u003Cp\u003EImplanted in the pulmonary artery, CardioMEMS\u0027 new heart sensor enables Class III heart-failure patients (considered to be in the moderate stage of heart failure) to take daily intracardiac pressure readings at home. This information is transmitted to a website, which enables physicians to monitor patients more effectively and alter medications when necessary. In fact, results from the recent clinical study showed a 40 percent reduction in hospitalizations when doctors used data from CardioMEMS\u0027 system to treat patients.\n\u003C\/p\u003E\n\u003Cp\u003ELaunched in 2001, CardioMEMS was co-founded by Dr. Jay Yadav, a cardiologist and director at the Cleveland Clinic Foundation at the time, and Mark Allen, a professor in Georgia Tech\u0027s School of Electrical and Computer Engineering and director of the school\u0027s MEMS research group. \n\u003C\/p\u003E\n\u003Cp\u003EDue to the unique nature of its technology, CardioMEMS elected to locate in Atlanta to be close to Allen and his students. ATDC accepted CardioMEMS into its incubator program shortly after the startup\u0027s formation.  The Georgia Research Alliance assisted with an industry partnership grant early in the company\u0027s development.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022ATDC has played an important role in CardioMEMS\u0027 success, especially during our early years,\u0022 said David Stern, CardioMEMS\u0027 senior vice president for scientific affairs and one of the company\u0027s first full-time employees. \n\u003C\/p\u003E\n\u003Cp\u003EBioscience companies face unique challenges, Stern explained: They have greater needs for capital, face higher technical risks and typically need FDA or other regulatory approval before they can market their products or services. And unlike many entrepreneurs that can start their companies in a garage or home office, bioscience companies require special facilities. \n\u003C\/p\u003E\n\u003Cp\u003ECardioMEMS was among the first tenants in ATDC\u0027s Biosciences Center, located within Georgia Tech\u0027s Environmental Science \u0026amp; Technology (ES\u0026amp;T) research center, which enabled the company to access wet labs equipped with special ventilation and purified water systems. CardioMEMS was also able to use Georgia Tech clean rooms for micromachining.\n\u003C\/p\u003E\n\u003Cp\u003EIf CardioMEMS had been required to build its own clean room, it would have cost millions of dollars and delayed R\u0026amp;D for months, Stern said. In addition, Georgia Tech\u0027s clean rooms have a broad array of specialized equipment, which enabled CardioMEMS to execute its prototyping faster -- and try different equipment to see what it would ultimately need to invest in.\n\u003C\/p\u003E\n\u003Cp\u003EThe physical proximity to other entrepreneurs and researchers in ES\u0026amp;T was also a plus. \u0022At one point we were next to another medical-device company, so it was easy for our staffs to have impromptu discussions walking down the hallways,\u0022 Stern said. Being on Georgia Tech\u0027s campus gave CardioMEMS access to a deep talent pool, and enabled the company to hire professors as consultants, graduate students as permanent employees and current students as interns.\n\u003C\/p\u003E\n\u003Cp\u003EAn important aspect of being able to use Georgia Tech facilities and hire talent was the lack of red tape. \u0022With most institutions, that becomes very complicated and you can spend a lot of time negotiating contracts rather than getting work done,\u0022 Stern explained. \u0022Yet ATDC was able to make it all really easy.\u0022\n\u003C\/p\u003E\n\u003Cp\u003E\u0022This may sound like a minor point, but it\u0027s not,\u0022 said Stern, noting that startup is a crucial time for any company, but especially for a biotech firm. \u0022It\u0027s during those early years that you have the least amount of money -- and the most to accomplish. You don\u0027t want to waste time or money on anything that doesn\u0027t involve progressing R\u0026amp;D or acquiring talent.\u0022 \n\u003C\/p\u003E\n\u003Cp\u003EToday CardioMEMS is located in Technology Enterprise Park, a biobusiness complex located south of the Georgia Tech campus, and FDA approval of its heart sensor would position the company for considerable growth. The heart sensor has faced a longer road to commercialization than the company\u0027s first product, however, its market potential is dramatically larger, said Stern, citing a patient population of more than 1.5 million compared to about 30,000 for the EndoSure sensor. \n\u003C\/p\u003E\n\u003Cp\u003EAlthough CardioMEMS is already contributing to Georgia\u0027s economy by generating new high-tech jobs, the company\u0027s success has broader implications, observed Nina Sawczuk, ATDC general manager.\n\u003C\/p\u003E\n\u003Cp\u003EThe $100 billion U.S. medical device industry is made up of thousands of small and medium-sized enterprises and a few large players. \u0022Medical device companies are located throughout the country, but concentrated in specific regions known for other high-technology industries, such as microelectronics and biotechnology,\u0022 Sawczuk explained. \u0022Georgia is among the top 10 states with the highest number of medical device companies and our focus is on supporting the small, innovative companies.\u0022 \n\u003C\/p\u003E\n\u003Cp\u003ETo this end Georgia Tech has partnered with Saint Joseph\u0027s Translational Research Institute, Piedmont Healthcare and the Georgia Research Alliance to launch the Global Center for Medical Innovation (GCMI), an initiative aimed at accelerating the development of next-generation medical devices and technology in the Southeast. \n\u003C\/p\u003E\n\u003Cp\u003E\u0022CardioMEMS is a catalyst for developing a next generation medical-device industry hub in Georgia,\u0022 Sawczuk continued. \u0022CardioMEMS marries MEMS technology with more traditional medical device technology. This is particularly exciting because the company is creating a new type of wireless product that is the future of the medical device industry. It is success stories such as CardioMEMS that the GCMI plans to replicate in the Southeast.\u0022\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E\nGeorgia Institute of Technology\u003Cbr \/\u003E\n75 Fifth Street, N.W., Suite 314\u003Cbr \/\u003E\nAtlanta, Georgia  30308  USA\n\u003C\/strong\u003E\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EMedia Relations Contacts\u003C\/strong\u003E: John Toon (404-894-6986)(\u003Ca href=\u0022mailto:jtoon@gatech.edu\u0022\u003Ejtoon@gatech.edu\u003C\/a\u003E) or Abby Robinson (404-385-3364)(\u003Ca href=\u0022mailto:abby@innovate.gatech.edu\u0022\u003Eabby@innovate.gatech.edu\u003C\/a\u003E).\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EWriter\u003C\/strong\u003E: T.J. Becker\n\u003C\/p\u003E\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"CardioMEMS Produces Implantable Monitoring Devices for Heart Patients"}],"field_summary":[{"value":"\u003Cp\u003EAn Atlanta medical device company that is based on Georgia Tech research has become an industry rising star, with a new product moving toward approval -- and more than 65 employees.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"A Georgia Tech-based company is a leader in medical devices."}],"uid":"27303","created_gmt":"2011-02-03 01:00:00","changed_gmt":"2016-10-08 03:08:06","author":"John Toon","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-02-03T00:00:00-05:00","iso_date":"2011-02-03T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"64055":{"id":"64055","type":"image","title":"CardioMEMS inspection","body":null,"created":"1449176720","gmt_created":"2015-12-03 21:05:20","changed":"1475894561","gmt_changed":"2016-10-08 02:42:41","alt":"CardioMEMS inspection","file":{"fid":"191923","name":"taf58980.jpg","image_path":"\/sites\/default\/files\/images\/taf58980_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/taf58980_0.jpg","mime":"image\/jpeg","size":1381825,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/taf58980_0.jpg?itok=R_txrWKy"}}},"media_ids":["64055"],"related_links":[{"url":"http:\/\/www.ece.gatech.edu\/","title":"School of Electrical and Computer Engineering"},{"url":"http:\/\/www.atdc.org\/","title":"ATDC"},{"url":"http:\/\/cmmt.gatech.edu\/","title":"Center for MEMS and Microsystems Technology"}],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"139","name":"Business"},{"id":"131","name":"Economic Development and Policy"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"135","name":"Research"}],"keywords":[{"id":"4238","name":"atdc"},{"id":"7672","name":"CardioMEMS"},{"id":"1925","name":"Electrical and Computer Engineering"},{"id":"2313","name":"Mark Allen"},{"id":"527","name":"medical"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EJohn Toon\u003C\/strong\u003E\u003Cbr \/\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=jt7\u0022\u003EContact John Toon\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-6986\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["jtoon@gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"63942":{"#nid":"63942","#data":{"type":"news","title":"Georgia Tech and TERMIS Partner for 2013 Annual Meeting","body":[{"value":"\u003Cp\u003EThe Tissue Engineering and Regenerative Medicine International Society (TERMIS) will partner with the Parker H. Petit Institute for Bioengineering and Bioscience at Georgia Tech in 2013 by hosting its annual North American Conference in Atlanta. \u003Cbr \/\u003E \u003Cbr \/\u003ETwo members of the Petit Institute\u2019s faculty have been designated to head the 2013 TERMIS conference. The conference chair will be Robert E. Guldberg, Ph.D., the director of the Petit Institute and professor in mechanical engineering and the program chair will be Todd McDevitt, PhD, associate professor in biomedical engineering and the director of the Stem Cell Engineering Center at Georgia Tech. \u003Cbr \/\u003E \u003Cbr \/\u003E\u201cWe are honored to be selected and look forward to putting on a great meeting,\u201d Guldberg said. TERMIS brings together an international community to promote discussion of the scientific challenges and therapeutic benefits for the development and application of the tissue engineering and regenerative medicine fields. TERMIS\u2019 mission is to promote worldwide science and technology advancement and education in these fields. It does so through regular worldwide conferences, publishing the Tissue Engineering journal that it endorses and providing quarterly newsletters and other communications for its members. \u003Cbr \/\u003E \u003Cbr \/\u003E\u201cBob and I are dedicated to creating a dynamic program that will honor the meetings of the past as well as introduce some new elements,\u201d McDevitt remarked. TERMIS has been evolving over the last decade. Its roots began in 2001 as an annual workshop called \u201cTissue Growth Engineering\u201d that was organized by the Pittsburgh Tissue Engineering Initiative. In 2004, this small workshop evolved into the larger, national meeting called Regenerate. In 2006, the Regenerate World Congress was held in Pittsburgh where the meeting had grown significantly and had a large international following. By the following year, the society was rebranded into TERMIS to encompass its international presence. The society has continued to grow and now has chapters in Europe and Asia. TERMIS is open to anyone engaged in research in the tissue engineering or regenerative medicine arenas. \u003Cbr \/\u003E \u003Cbr \/\u003EThe 2011 TERMIS North American conference was held in Houston, Texas and in 2012 the entire society will come together for the TERMIS World Congress in Vienna, Austria.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EThe Tissue Engineering and Regenerative Medicine International Society (TERMIS) will partner with the Institute for Bioengineering and Bioscience (IBB) at Georgia Tech in 2013 by hosting its annual North American Conference in Atlanta.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Georgia Tech and TERMIS Partner for 2013 Annual Meeting"}],"uid":"27224","created_gmt":"2011-01-14 01:00:00","changed_gmt":"2016-10-08 03:08:06","author":"Megan McDevitt","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-01-18T00:00:00-05:00","iso_date":"2011-01-18T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"64111":{"id":"64111","type":"image","title":"TERMIS","body":null,"created":"1449176720","gmt_created":"2015-12-03 21:05:20","changed":"1475894559","gmt_changed":"2016-10-08 02:42:39","alt":"TERMIS","file":{"fid":"191940","name":"termis_logo_1.jpg","image_path":"\/sites\/default\/files\/images\/termis_logo_1_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/termis_logo_1_0.jpg","mime":"image\/jpeg","size":127070,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/termis_logo_1_0.jpg?itok=ha69ZdMV"}}},"media_ids":["64111"],"related_links":[{"url":"http:\/\/ibb.gatech.edu\/","title":"Parker H. Petit Institute for Bioengineering and Bioscience"},{"url":"http:\/\/www.termis.org\/","title":"TERMIS"},{"url":"http:\/\/scec.gatech.edu\/","title":"Stem Cell Engineering Center"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"131","name":"Economic Development and Policy"},{"id":"132","name":"Institute Leadership"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"133","name":"Special Events and Guest Speakers"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"}],"keywords":[{"id":"1489","name":"Regenerative Medicine"},{"id":"11629","name":"Robert Guldberg"},{"id":"4891","name":"Tissue Engineering"},{"id":"760","name":"Todd McDevitt"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EMegan McDevitt\u003C\/strong\u003E\u003Cbr \/\u003EIBB\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=mm504\u0022\u003EContact Megan McDevitt\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-7001\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["megan.mcdevitt@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"65612":{"#nid":"65612","#data":{"type":"external_news","title":"Atlanta among 54 major markets adding private-sector jobs","body":[{"value":"\u003Cp\u003EMore than half of the nation\u2019s 100 largest labor markets are now adding \njobs, and Atlanta and Augusta are two of them, according an analysis of \nnew federal employment data.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27195","created_gmt":"2011-04-18 13:23:54","changed_gmt":"2016-10-08 02:24:27","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","publication":"breakthrough cases","field_article_url":"","publication_url":"http:\/\/ibb.gatech.edu\/industry\/atlanta-among-54-major-markets-adding-private-sector-jobs","dateline":{"date":"2011-01-06T00:00:00-05:00","iso_date":"2011-01-06T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"140","name":"Cancer Research"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"150","name":"Physics and Physical Sciences"}],"keywords":[{"id":"12824","name":"Atlanta among 54 major markets adding private-sector jobs"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"62742":{"#nid":"62742","#data":{"type":"news","title":"State Labs on Cutting Edge","body":[{"value":"\u003Cp\u003EGeorgia\u0027s small community of cutting-edge stem cell researchers got a boost this month when the first-ever trial testing a human embryonic stem cell therapy began at Atlanta\u0027s Shepherd Center.\n\u003C\/p\u003E\n\u003Cp\u003EWhen it comes to stem cell research, California and Massachusetts lead the nation with hot-shot scientists and well-funded laboratories. But Georgia has its own stable of scientists working on the stem cell frontier, and the groundbreaking experiment launched on Peachtree Street could help raise the profile of Georgia\u0027s stem cell efforts.\n\u003C\/p\u003E\n\u003Cp\u003EEmory University, Georgia Tech and the University of Georgia all have scientists conducting advanced stem cell research. And the Shepherd Center can now boast that it is the first site in the world to test the safety of a treatment that scientists hope will someday help paralyzed patients walk again.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022Shepherd has now established their own precedent for running a stem cell-based clinical trial and that level of experience and expertise will be coveted,\u0022 said Hans Keirstead, a neuroscientist at the University of California Irvine who pioneered the therapy being tested in the trial. \u0022Absolutely, they will have a real leg up on the rest of the world.\u0022 \n\u003C\/p\u003E\n\u003Cp\u003E\u003Ca href=\u0027http:\/\/www6.lexisnexis.com\/publisher\/EndUser?Action=UserDisplayFullDocument\u0026amp;orgId=574\u0026amp;topicId=100020422\u0026amp;docId=l:1284069566\u0026amp;isRss=true\u0027\u003ERead Full Article\u003C\/a\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Georgia\u0027s small community of cutting-edge stem cell researchers got a boost this month when the first-ever trial testing a human embryonic stem cell therapy began at Atlanta\u0027s Shepherd Center.\n\nWhen it comes to stem cell research, California and Massachusetts lead the nation with hot-shot scientists and well-funded laboratories. But Georgia has its own stable of scientists working on the stem cell frontier, and the groundbreaking experiment launched on Peachtree Street could help raise the profile of Georgia\u0027s stem cell efforts.","format":"limited_html"}],"field_summary_sentence":[{"value":"State Labs on Cutting Edge"}],"uid":"27349","created_gmt":"2010-10-18 00:00:00","changed_gmt":"2016-10-08 03:07:46","author":"Floyd Wood","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2010-10-18T00:00:00-04:00","iso_date":"2010-10-18T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"140","name":"Cancer Research"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"},{"id":"150","name":"Physics and Physical Sciences"}],"keywords":[{"id":"109","name":"Georgia Tech"},{"id":"1487","name":"GTEC"},{"id":"248","name":"IBB"},{"id":"167130","name":"Stem Cells"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EFloyd Wood\u003C\/strong\u003E\u003Cbr \/\u003EIBB\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=fwood3\u0022\u003EContact Floyd Wood\u003C\/a\u003E","format":"limited_html"}],"email":["floyd.wood@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"60431":{"#nid":"60431","#data":{"type":"news","title":"NSF Awards $3M Stem Cell Bio-Manufacturing Program to Georgia Tech","body":[{"value":"\u003Cp\u003EThe National Science Foundation (NSF) has awarded $3 million to the Georgia Institute of Technology to fund a unique research program on stem cell bio-manufacturing. The program is specifically focused on developing engineering methods for stem cell production, in order to meet the anticipated demand for stem cells. The award comes through the NSF\u0027s Integrative Graduate Education and Research Traineeship (IGERT) Program, which supports innovation in graduate education in fields that cross academic disciplines and have broad societal impact.\u003C\/p\u003E\u003Cp\u003EWhile stem cell research is on the verge of broadly impacting many elements of the medical field -- regenerative medicine, drug discovery and development, cell-based diagnostics and cancer -- the bio-process engineering that will be required to manufacture sufficient quantities of functional stem cells for these diagnostic and therapeutic purposes has not been rigorously explored. \u003C\/p\u003E\u003Cp\u003E\u0022Successfully integrating knowledge of stem cell biology with bioprocess engineering and process development into single individuals is the challenging goal of this program,\u0022 said Todd McDevitt, an associate professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University and a Petit Faculty Fellow in the Parker H. Petit Institute for Bioengineering and Biosciences at Georgia Tech. \u003C\/p\u003E\u003Cp\u003EMcDevitt is leading the IGERT with Robert M. Nerem, professor emeritus of the George W. Woodruff School of Mechanical Engineering at Georgia Tech. Nerem is also director of the Georgia Tech\/Emory Center (GTEC) for Regenerative Medicine, which will administer this award.\u003C\/p\u003E\u003Cp\u003EPh.D. students funded by Georgia Tech\u0027s stem cell bio-manufacturing IGERT will receive interdisciplinary educational training in the biology, engineering, enabling technologies, commercialization and public policy related to stem cells. Their research efforts will focus on developing innovative engineering approaches to bridge the gap between basic discoveries made in stem cell biology and therapeutic stem cell-based technologies. \u003C\/p\u003E\u003Cp\u003E\u0022This program provides a unique opportunity for engineers to generate standardized and quantitative methods for stem cell isolation, characterization, propagation and differentiation,\u0022 said Nerem. \u0022These techniques must be developed in a scalable manner to efficiently produce sufficient numbers of stem cells and derivatives in accessible formats in order to yield a spectrum of novel therapeutic and diagnostic applications of stem cells.\u0022 \u003C\/p\u003E\u003Cp\u003EThe Georgia Tech program is centered around three main research thrusts, which focus on several critical technologies that must be developed to enable the application and use of stem cell-based products: \u003C\/p\u003E\u003Cp\u003E\u2022 Creating reproducible, controlled and scalable methods to expand and differentiate stem cells with defined phenotypes and epigenetic states. \u003C\/p\u003E\u003Cp\u003E\u2022 Developing reliable, rapid and quantifiable methods to characterize the composition and function of stem cells to be generated. \u003C\/p\u003E\u003Cp\u003E\u2022 Designing low-cost systems capable of producing large populations of defined stem cells and derivatives.\u003C\/p\u003E\u003Cp\u003EStudents in the program will be able to take advantage of the core facilities provided by the new Stem Cell Engineering Center at Georgia Tech, which is directed by McDevitt. Technologies developed by the students supported through this IGERT will be rapidly integrated into academic and industrial stem cell practices and cell-based products. \u003C\/p\u003E\u003Cp\u003EThe award will support 30 new Ph.D. students over the next five years and brings together more than two dozen faculty members from Georgia Tech, Emory University, the University of Georgia and the Morehouse School of Medicine. In addition, plans are being made for students to participate in international research collaborations with the National University of Ireland at Galway, Imperial College London, the University of Cambridge and the University of Toronto. \u003C\/p\u003E\u003Cp\u003E\u0022We anticipate this program will produce the future leaders and innovators in the field of stem cell bio-manufacturing who will contribute significantly at the interface of stem cell engineering, biology and therapy,\u0022 added McDevitt. \u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003EGeorgia Institute of Technology\u003Cbr \/\u003E75 Fifth Street, N.W., Suite 314\u003Cbr \/\u003EAtlanta, Georgia 30308 USA \u003C\/strong\u003E Abby Vogel Robinson (404-385-3364; \u003Ca href=\u0022mailto:abby@innovate.gatech.edu\u0022\u003Eabby@innovate.gatech.edu\u003C\/a\u003E) or John Toon (404-894-6986; \u003Ca href=\u0022mailto:jtoon@gatech.edu\u0022\u003Ejtoon@gatech.edu\u003C\/a\u003E) \u003C\/p\u003E\u003Cp\u003EMedia Relations Contacts:\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EWriter:\u003C\/strong\u003E Abby Vogel Robinson\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"Nerem and McDevitt will lead Integrative Graduate Education and Research Traineeship (IGERT) Program"}],"field_summary":[{"value":"\u003Cp\u003EThe NSF has awarded $3 million to Georgia Tech to fund a unique research program on stem cell bio-manufacturing. The effort is focused on developing engineering methods for stem cell production to meet the anticipated demand for stem cells.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"A stem cell bio-manufacturing research and education program award has been awarded to Georgia Tech."}],"uid":"27206","created_gmt":"2010-08-15 00:00:00","changed_gmt":"2016-10-08 03:07:15","author":"Abby Vogel Robinson","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2010-08-16T00:00:00-04:00","iso_date":"2010-08-16T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"60432":{"id":"60432","type":"image","title":"Todd McDevitt","body":null,"created":"1449176267","gmt_created":"2015-12-03 20:57:47","changed":"1475894523","gmt_changed":"2016-10-08 02:42:03","alt":"Todd McDevitt","file":{"fid":"191123","name":"tnh17927.jpg","image_path":"\/sites\/default\/files\/images\/tnh17927_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tnh17927_0.jpg","mime":"image\/jpeg","size":1233833,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tnh17927_0.jpg?itok=vgTJzXrP"}},"60433":{"id":"60433","type":"image","title":"Robert Nerem","body":null,"created":"1449176267","gmt_created":"2015-12-03 20:57:47","changed":"1475894523","gmt_changed":"2016-10-08 02:42:03","alt":"Robert Nerem","file":{"fid":"191124","name":"tao17927.jpg","image_path":"\/sites\/default\/files\/images\/tao17927_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tao17927_0.jpg","mime":"image\/jpeg","size":1376960,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tao17927_0.jpg?itok=cUXTKsm5"}},"60434":{"id":"60434","type":"image","title":"Robert Nerem \u0026 Todd McDevitt","body":null,"created":"1449176267","gmt_created":"2015-12-03 20:57:47","changed":"1475894523","gmt_changed":"2016-10-08 02:42:03","alt":"Robert Nerem \u0026 Todd McDevitt","file":{"fid":"191125","name":"tpb17928.jpg","image_path":"\/sites\/default\/files\/images\/tpb17928_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tpb17928_0.jpg","mime":"image\/jpeg","size":1599704,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tpb17928_0.jpg?itok=qHDHZJYj"}}},"media_ids":["60432","60433","60434"],"related_links":[{"url":"http:\/\/www.me.gatech.edu\/faculty\/nerem.shtml","title":"Robert Nerem"},{"url":"http:\/\/www.bme.gatech.edu\/facultystaff\/faculty_record.php?id=78","title":"Todd McDevitt"},{"url":"http:\/\/www.me.gatech.edu\/","title":"George W. Woodruff School of Mechanical Engineering"},{"url":"http:\/\/www.bme.gatech.edu\/","title":"Wallace H. Coulter Department of Biomedical Engineering"}],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"140","name":"Cancer Research"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"135","name":"Research"}],"keywords":[{"id":"167413","name":"Stem Cell"},{"id":"171009","name":"stem cell bio-manufacturing"},{"id":"171010","name":"Stem Cell Development"},{"id":"169496","name":"stem cell differentiation"},{"id":"171011","name":"stem cell industry"},{"id":"171012","name":"stem cell production"},{"id":"167139","name":"Stem Cell Research"},{"id":"171013","name":"stem cell therapy"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EAbby Vogel Robinson\u003C\/strong\u003E\u003Cbr \/\u003EResearch News and Publications\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=avogel6\u0022\u003EContact Abby Vogel Robinson\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-3364\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["abby@innovate.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"60407":{"#nid":"60407","#data":{"type":"news","title":"NIH EUREKA Award Will Enable Design of New Brain Tumor Treatment","body":[{"value":"\u003Cp\u003EThe Georgia Institute of Technology has received a EUREKA grant from the National Institutes of Health (NIH) to design a new way to treat invasive brain tumors by capturing the migrating cells that spread the disease. The EUREKA -- Exceptional, Unconventional Research Enabling Knowledge Acceleration -- program helps scientists test new, unconventional ideas or tackle major methodological or technical challenges.\n\u003C\/p\u003E\n\u003Cp\u003EThe research team plans to develop a system that will excavate brain tumor cells by directing them away from their location in the interior of the brain to a more external location where they can be removed or killed. Nanofiber-based polymer thin films coated with biochemical cues will be aligned in the brain to provide a corridor for tumor cells to follow to a gel-based \u0027sink\u0027 where they will be captured and safely removed or encouraged to die through chemical signaling.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022We believe this is the first attempt to exploit the invasive, migrating properties of brain tumors by engineering a path for the tumors to move away from the primary site to a location where treatment can occur,\u0022 said lead investigator Ravi Bellamkonda, a professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University.\n\u003C\/p\u003E\n\u003Cp\u003ECollaborating with Bellamkonda on this project are Tobey MacDonald, director of the pediatric neuro-oncology program at the Aflac Cancer Center and Blood Disorders Service of Children\u0027s Healthcare of Atlanta and an associate professor of pediatrics at the Emory University School of Medicine; and Barun Brahma, a pediatric neurosurgeon at Children\u0027s Healthcare of Atlanta. The initial partnership between the researchers began with seed funding from the Georgia Cancer Coalition and Ian\u0027s Friends Foundation.\n\u003C\/p\u003E\n\u003Cp\u003EThe National Cancer Institute is providing more than $1 million for the EUREKA grant. For the project, Bellamkonda, MacDonald and Brahma are focusing on treating medulloblastomas -- highly malignant brain tumors that account for more than 20 percent of pediatric brain tumors.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022Medulloblastoma is the most common malignant brain tumor we see in children, but unfortunately the five-year survival rates for children with this cancer only range from 50 to 70 percent and the majority of survivors have a significantly reduced quality of life as a result of treatment-related toxicities,\u0022 said MacDonald, who is also a Georgia Cancer Coalition Distinguished Scholar. \u0022An increasing number of survivors are also at risk for developing secondary malignancies as a result of the treatment we now administer. Clearly we have to do a much better job at treating these tumors; however, improving survival while reducing the toxic effects of treatment will require a highly innovative approach.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EMedulloblastoma treatment currently involves surgery followed by radiation therapy to the entire brain and spine and up to one year of intensive intravenous chemotherapy. However, radiation is often delayed or omitted altogether in young children due to its debilitating long-term side effects on the developing central nervous system.\n\u003C\/p\u003E\n\u003Cp\u003EThese changes to the timing of radiation administration can adversely impact survival. And while surgery is a mainstay of treatment, it too can cause a significant loss of cognitive and neurological function due to the critical areas of the brain that may be involved by the tumor\u0027s spread but require an extensive surgical area to remove as much of the tumor as possible.\n\u003C\/p\u003E\n\u003Cp\u003EThis EUREKA grant aims to address the urgent need to develop therapies to safely treat invasive medulloblastomas in children.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022Our plan is to deliver the tumor to the drug -- by directing tumor cells to a specially engineered gel that can be removed or designed to kill the cells -- rather than the current strategy of delivering the drug to the tumor, which is problematic due to the irregular vasculature and poor diffusivity of the tumor tissue,\u0022 explained Bellamkonda, who is also a Georgia Cancer Coalition Distinguished Scholar.\n\u003C\/p\u003E\n\u003Cp\u003EThe researchers plan to design a polymer thin film system that will include topographical and biochemical cues similar to those that guide the initial brain tumor invasion. The thin films will be rolled up and deployed with minimally invasive catheters. Because neural tissue will not be suctioned and the films are very thin, there should be minimal tissue and tumor disruption.\n\u003C\/p\u003E\n\u003Cp\u003EThe films will also be non-toxic to the patient because they will be engineered with biocompatible, stable polymers. In previous studies, the polymers have been implanted in the nervous systems of small animals for more than 16 weeks with no adverse tissue reactions.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022This research represents a radical approach to treating invasive tumors that is based on the universal properties and mechanics of cell motility and the migration characteristic of metastasis, regardless of the molecular and genetic origins of the tumor,\u0022 added Bellamkonda.\n\u003C\/p\u003E\n\u003Cp\u003EIf successful, this approach would identify a new and innovative way to treat pediatric medulloblastomas and has the potential to open a new avenue for the treatment of other invasive solid tumors, such as brain stem tumors. These cancers are incurable because they are located in an inoperable region and\/or they are resistant or inaccessible to the delivery of chemotherapy agents. \u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EThe Georgia Institute of Technology has received a EUREKA grant from the National Cancer Institute to design a new way to treat invasive brain tumors by capturing the migrating cells that spread the disease.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"$1M grant awarded to Coulter Department professor Ravi Bellamkonda"}],"uid":"27349","created_gmt":"2010-08-10 00:00:00","changed_gmt":"2016-10-08 03:07:15","author":"Floyd Wood","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2010-08-10T00:00:00-04:00","iso_date":"2010-08-10T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"132","name":"Institute Leadership"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"},{"id":"150","name":"Physics and Physical Sciences"}],"keywords":[{"id":"9492","name":"bellamkonda"},{"id":"10378","name":"EUREKA Grant"},{"id":"1487","name":"GTEC"},{"id":"248","name":"IBB"},{"id":"2076","name":"NIH"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EAbby Vogel Robinson\u003C\/strong\u003E\u003Cbr \/\u003EResearch News and Publications\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=avogel6\u0022\u003EContact Abby Vogel Robinson\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-3364\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["abby@innovate.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"60096":{"#nid":"60096","#data":{"type":"news","title":"Vaccine-Delivery Patch with Dissolving Microneedles Boosts Protection","body":[{"value":"\u003Cp\u003EA new vaccine-delivery patch based on hundreds of microscopic needles that dissolve into the skin could allow persons without medical training to painlessly administer vaccines -- while providing improved immunization against diseases such as influenza.\u003C\/p\u003E\u003Cp\u003EPatches containing micron-scale needles that carry vaccine with them as they dissolve into the skin could simplify immunization programs by eliminating the use of hypodermic needles -- and their \u0022sharps\u0022 disposal and re-use concerns. Applied easily to the skin, the microneedle patches could allow self-administration of vaccine during pandemics and simplify large-scale immunization programs in developing nations. \u003C\/p\u003E\u003Cp\u003EDetails of the dissolving microneedle patches and immunization benefits observed in experimental mice were reported July 18th in the advance online publication of the journal \u003Cem\u003ENature Medicine\u003C\/em\u003E. Conducted by researchers from Emory University and the Georgia Institute of Technology, the study is believed to be the first to evaluate the immunization benefits of dissolving microneedles. The research was supported by the National Institutes of Health (NIH). \u003C\/p\u003E\u003Cp\u003E\u0022In this study, we have shown that a dissolving microneedle patch can vaccinate against influenza at least as well, and probably better than, a traditional hypodermic needle,\u0022 said Mark Prausnitz, a professor in the Georgia Tech School of Chemical and Biomolecular Engineering. \u003C\/p\u003E\u003Cp\u003EJust 650 microns in length and assembled into an array of 100 needles for the mouse study, the dissolving microneedles penetrate the outer layers of skin. Beyond their other advantages, the dissolving microneedles appear to provide improved immunity to influenza when compared to vaccination with hypodermic needles. \u003C\/p\u003E\u003Cp\u003E\u0022The skin is a particularly attractive site for immunization because it contains an abundance of the types of cells that are important in generating immune responses to vaccines,\u0022 said Richard Compans, professor of microbiology and immunology at Emory University School of Medicine. \u003C\/p\u003E\u003Cp\u003EIn the study, one group of mice received the influenza vaccine using traditional hypodermic needles injecting into muscle; another group received the vaccine through dissolving microneedles applied to the skin, while a control group had microneedle patches containing no vaccine applied to their skin. When infected with influenza virus 30 days later, both groups that had received the vaccine remained healthy while mice in the control group contracted the disease and died. \u003C\/p\u003E\u003Cp\u003EThree months after vaccination, the researchers also exposed a different group of immunized mice to flu virus and found that animals vaccinated with microneedles appeared to have a better \u0022recall\u0022 response to the virus and thus were able to clear the virus from their lungs more effectively than those that received vaccine with hypodermic needles. \u003C\/p\u003E\u003Cp\u003E\u0022Another advantage of these microneedles is that the vaccine is present as a dry formulation, which will enhance its stability during distribution and storage,\u0022 said Ioanna Skountzou, an Emory University assistant professor. \u003C\/p\u003E\u003Cp\u003EPressed into the skin, the microneedles quickly dissolve in bodily fluids, leaving only the water-soluble backing. The backing can be discarded because it no longer contains any sharps. \u003C\/p\u003E\u003Cp\u003E\u0022We envision people getting the patch in the mail or at a pharmacy and then self administering it at home,\u0022 said Sean Sullivan, the study\u2019s lead author from Georgia Tech. \u0022Because the microneedles on the patch dissolve away into the skin, there would be no dangerous sharp needles left over.\u0022 \u003C\/p\u003E\u003Cp\u003EThe microneedle arrays were made from a polymer material, poly-vinyl pyrrolidone, that has been shown to be safe for use in the body. Freeze-dried vaccine was mixed with the vinyl-pyrrolidone monomer before being placed into microneedle molds and polymerized at room temperature using ultraviolet light. \u003C\/p\u003E\u003Cp\u003EIn many parts of the world, poor medical infrastructure leads to the re-use of hypodermic needles, contributing to the spread of diseases such as HIV and hepatitis B. Dissolving microneedle patches would eliminate re-use while allowing vaccination to be done by personnel with minimal training. \u003C\/p\u003E\u003Cp\u003EThough the study examined only the administration of flu vaccine with the dissolving microneedles, the technique should be useful for other immunizations. If mass-produced, the microneedle patches are expected to cost about the same as conventional needle-and-syringe techniques, and may lower the overall cost of immunization programs by reducing personnel costs and waste disposal requirements, Prausnitz said. \u003C\/p\u003E\u003Cp\u003EBefore dissolving microneedles can be made widely available, however, clinical studies will have to be done to assure safety and effectiveness. Other vaccine formulation techniques may also be studied, and researchers will want to better understand why vaccine delivery with dissolving microneedles has been shown to provide better protection. \u003C\/p\u003E\u003Cp\u003EBeyond those already mentioned, the study involved Jeong-Woo Lee, Vladimir Zarnitsyn, Seong-O Choi and Niren Murthy from Georgia Tech, and Dimitrios Koutsonanos and Maria del Pilar Martin from Emory University. \u003C\/p\u003E\u003Cp\u003E\u0022The dissolving microneedle patch could open up many new doors for immunization programs by eliminating the need for trained personnel to carry out the vaccination,\u0022 Prausnitz said. \u0022This approach could make a significant impact because it could enable self-administration as well as simplify vaccination programs in schools and assisted living facilities.\u0022 \u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003EGeorgia Institute of Technology\u003Cbr \/\u003E75 Fifth Street, N.W., Suite 314\u003Cbr \/\u003EAtlanta, Georgia 30308 USA\u003C\/strong\u003E \u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EMedia Relations Contacts\u003C\/strong\u003E: John Toon, Georgia Tech (404-894-6986) (\u003Ca href=\u0022mailto:jtoon@gatech.edu\u0022\u003Ejtoon@gatech.edu\u003C\/a\u003E), Holly Korschun, Emory University (404-727-3990) (\u003Ca href=\u0022mailto:hkorsch@emory.edu\u0022\u003Ehkorsch@emory.edu\u003C\/a\u003E) or Abby Vogel Robinson, Georgia Tech (404-385-3364) (\u003Ca href=\u0022mailto:abby@innovate.gatech.edu\u0022\u003Eabby@innovate.gatech.edu\u003C\/a\u003E). \u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EWriter\u003C\/strong\u003E: John Toon \u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"Device Replaces Hypodermic Needles to Eliminate Sharp Waste"}],"field_summary":[{"value":"\u003Cp\u003EA new vaccine-delivery patch based on hundreds of microscopic needles that dissolve into the skin could allow persons without medical training to painlessly administer vaccines \u2013 while providing improved immunization against diseases such as influenza.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Dissolving microneedles offer a new vaccine-delivery solution"}],"uid":"27303","created_gmt":"2010-07-18 00:00:00","changed_gmt":"2016-10-08 03:07:11","author":"John Toon","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2010-07-18T00:00:00-04:00","iso_date":"2010-07-18T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"60097":{"id":"60097","type":"image","title":"Dissolving microneedles on fingertip","body":null,"created":"1449176239","gmt_created":"2015-12-03 20:57:19","changed":"1475894520","gmt_changed":"2016-10-08 02:42:00","alt":"Dissolving microneedles on fingertip","file":{"fid":"191051","name":"tvn90868.jpg","image_path":"\/sites\/default\/files\/images\/tvn90868_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tvn90868_0.jpg","mime":"image\/jpeg","size":428627,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tvn90868_0.jpg?itok=XnfaXzLx"}},"60098":{"id":"60098","type":"image","title":"Dissolving microneedles on application.","body":null,"created":"1449176239","gmt_created":"2015-12-03 20:57:19","changed":"1475894520","gmt_changed":"2016-10-08 02:42:00","alt":"Dissolving microneedles on application.","file":{"fid":"191052","name":"tvw90868.jpg","image_path":"\/sites\/default\/files\/images\/tvw90868_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tvw90868_0.jpg","mime":"image\/jpeg","size":534894,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tvw90868_0.jpg?itok=0nHMgk9n"}},"60099":{"id":"60099","type":"image","title":"Dissolving microneedles after on minute.","body":null,"created":"1449176239","gmt_created":"2015-12-03 20:57:19","changed":"1475894520","gmt_changed":"2016-10-08 02:42:00","alt":"Dissolving microneedles after on minute.","file":{"fid":"191053","name":"tjx90868.jpg","image_path":"\/sites\/default\/files\/images\/tjx90868_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tjx90868_0.jpg","mime":"image\/jpeg","size":603655,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tjx90868_0.jpg?itok=LDwBMIKz"}}},"media_ids":["60097","60098","60099"],"related_links":[{"url":"http:\/\/www.chbe.gatech.edu\/fac_staff\/faculty\/prausnitz.php","title":"Mark Prausnitz"},{"url":"http:\/\/microbiology.emory.edu\/compans_r.html","title":"Richard Compans"},{"url":"http:\/\/www.chbe.gatech.edu\/","title":"School of Chemical \u0026 Biomolecular Engineering"},{"url":"http:\/\/www.med.emory.edu\/","title":"Emory University School of Medicine"}],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"145","name":"Engineering"},{"id":"147","name":"Military Technology"},{"id":"135","name":"Research"}],"keywords":[{"id":"296","name":"Flu"},{"id":"764","name":"immunization"},{"id":"765","name":"influenza"},{"id":"494","name":"Microneedle"},{"id":"170850","name":"skin"},{"id":"763","name":"vaccine"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EJohn Toon\u003C\/strong\u003E\u003Cbr \/\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=jt7\u0022\u003EContact John Toon\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-6986\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["jtoon@gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"48923":{"#nid":"48923","#data":{"type":"news","title":"Delivering Stem Cells Improves Repair of Major Bone Injuries in Rats","body":[{"value":"\u003Cp\u003EA study published this week reinforces the potential value of stem cells in repairing major injuries involving the loss of bone structure.  \u003C\/p\u003E\n\u003Cp\u003EThe study shows that delivering stem cells on a polymer scaffold to treat large areas of missing bone leads to improved bone formation and better mechanical properties compared to treatment with the scaffold alone. This type of therapeutic treatment could be a potential alternative to bone grafting operations.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022Massive bone injuries are among the most challenging problems that orthopedic surgeons face, and they are commonly seen as a result of accidents as well as in soldiers returning from war,\u0022 said the study\u0027s lead author Robert Guldberg, a professor in Georgia Tech\u0027s Woodruff School of Mechanical Engineering. \u0022This study shows that there is promise in treating these injuries by delivering stem cells to the injury site. These are injuries that would not heal without significant medical intervention.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EDetails of the research were published in the early edition of the journal \u003Cem\u003EProceedings of the National Academy of Sciences\u003C\/em\u003E on January 11, 2010. This work was funded by the National Institutes of Health and the National Science Foundation.\n\u003C\/p\u003E\n\u003Cp\u003EThe study was conducted in rats in which two bone gaps eight millimeters in length were created to simulate massive injuries. One gap was treated with a polymer scaffold seeded with stem cells and the other with scaffold only. The results showed that injuries treated with the stem cell scaffolds showed significantly more bone growth than injuries treated with scaffolds only. \n\u003C\/p\u003E\n\u003Cp\u003EGuldberg and mechanical engineering graduate student Kenneth Dupont experimented with scaffolds containing two different types of human stem cells -- bone marrow-derived mesenchymal adult stem cells and amniotic fluid fetal stem cells. \n\u003C\/p\u003E\n\u003Cp\u003E\u0022We were able to directly evaluate the therapeutic potential of human stem cells to repair large bone defects by implanting them into rats with a reduced immune system,\u0022 explained Guldberg, who is also the director of the Petit Institute for Bioengineering and Bioscience at Georgia Tech.\u003C\/p\u003E\n\u003Cp\u003EMicro-CT measurements showed no significant differences in bone regeneration between the two stem cell groups. However, combining the two types of stem cells produced significantly higher bone volume and strength compared to scaffolds without cellular augmentation.\n\u003C\/p\u003E\n\u003Cp\u003EAlthough stem cell delivery significantly enhanced bone growth and biomechanical properties, it was not able to consistently repair the injury. Eight weeks after the treatment, new bone bridged the gaps in four of nine defects treated with scaffolds seeded with adult stem cells, one of nine defects treated with scaffolds seeded with fetal stem cells, and none of the defects treated with the scaffold alone.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022We thought that the functional regeneration of the bone defects may have been limited by stem cells migrating away from the injury site, so we decided to investigate the fate and distribution of the delivered cells,\u0022 said Guldberg.\n\u003C\/p\u003E\n\u003Cp\u003ETo do this, Guldberg labeled stem cells with fluorescent quantum dots -- nanometer-scale particles that emit light when excited by near-infrared radiation -- to track the distribution of stem cells after delivery on the scaffolds and completed the same experiments as previously described. \n\u003C\/p\u003E\n\u003Cp\u003EThroughout the entire study, the researchers observed significant fluorescence at the stem cell scaffold sites. However, beginning seven to 10 days after treatment, signals appeared at the scaffold-only sites. Additional analysis with immunostaining revealed that the quantum dots present at the scaffold-only sites were contained in inflammatory cells called macrophages that had taken up quantum dots released from dead stem cells.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022While our overall study shows that stem cell therapy has a lot of promise for treating massive bone defects, this experiment shows that we still need to develop an improved way of delivering the stem cells so that they stay alive longer and thus remain at the injury site longer,\u0022 explained Guldberg.\u003C\/p\u003E\n\u003Cp\u003EThe researchers also found that the quantum dots diminished the function of the transplanted stem cells and thus their therapeutic effect. When the stem cells were labeled with quantum dots, the results showed a failure to enhance bone formation or bridge defects. However, the same low concentration of quantum dots did not affect cell viability or the ability of the stem cells to become bone cells in laboratory studies. \n\u003C\/p\u003E\n\u003Cp\u003E\u0022Although in vitro laboratory studies remain important, this work provides further evidence that well-characterized in vivo models are necessary to test the ability of regenerative tissue strategies to effectively integrate and restore function in complex living organisms,\u0022 added Guldberg. \u0022Improved methods of non-invasive cell tracking that do not alter cell function in vivo are needed to optimize stem cell delivery strategies and compare the effectiveness of different stem cell sources for tissue regeneration.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EGuldberg is currently exploring alternative cell tracking methods, such as genetically modifying the stem cells to express green fluorescent protein and\/or other luminescent enzymes such as luciferase. He is also investigating the addition of programming cues to the scaffold that will direct the stem cells to differentiate into bone cells. These signals may be particularly effective for fetal stem cells, which are believed to be more primitive than adult stem cells, according to Guldberg. \n\u003C\/p\u003E\n\u003Cp\u003ELessons learned from the current work are also being applied to develop effective stem cell therapies for severe composite injuries to multiple tissues including bone, nerve, vasculature and muscle. This follow-on work is being conducted in the Georgia Tech Center for Advanced Bioengineering for Soldier Survivability in collaboration with Ravi Bellamkonda and Barbara Boyan, professors in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University.\n\u003C\/p\u003E\n\u003Cp\u003EOther authors on the paper include Andres Garcia, professor and Woodruff Faculty Fellow in Georgia Tech\u0027s Woodruff School of Mechanical Engineering and the Petit Institute for Bioengineering and Bioscience; Georgia Tech research scientist Hazel Stevens, Georgia Tech graduate student Joel Boerckel; and National University of Ireland medical student Kapil Sharma.\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cem\u003EThis work was funded by grant number R01-AR051336 from the National Institutes of Health (NIH) and by grant number EEC-9731643 from the National Science Foundation (NSF). The content is solely the responsibility of the principal investigator and does not necessarily represent the official views of the NIH or NSF.\u003C\/em\u003E\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E\nGeorgia Institute of Technology\u003Cbr \/\u003E\n75 Fifth Street, N.W., Suite 314\u003Cbr \/\u003E\nAtlanta, Georgia  30308  USA\n\u003C\/strong\u003E\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EMedia Relations Contacts:\u003C\/strong\u003E Abby Vogel (avogel@gatech.edu; 404-385-3364) or John Toon (jtoon@gatech.edu; 404-894-6986).\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EWriter:\u003C\/strong\u003E Abby Vogel\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"A new study published this week shows that delivering stem cells on a polymer scaffold to treat large areas of missing bone leads to improved bone formation and better mechanical properties compared to treatment with scaffold alone.","format":"limited_html"}],"field_summary_sentence":[{"value":"Study reinforces potential value of stem cells to repair bone in"}],"uid":"27206","created_gmt":"2010-01-11 01:00:00","changed_gmt":"2016-10-08 03:04:04","author":"Abby Vogel Robinson","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2010-01-11T00:00:00-05:00","iso_date":"2010-01-11T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"48924":{"id":"48924","type":"image","title":"Robert Guldberg bone regeneration","body":null,"created":"1449175408","gmt_created":"2015-12-03 20:43:28","changed":"1475894463","gmt_changed":"2016-10-08 02:41:03","alt":"Robert Guldberg bone regeneration","file":{"fid":"101291","name":"try39853.jpg","image_path":"\/sites\/default\/files\/images\/try39853_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/try39853_0.jpg","mime":"image\/jpeg","size":1255705,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/try39853_0.jpg?itok=V0huypJw"}},"48925":{"id":"48925","type":"image","title":"Bone regeneration with stem cell scaffold","body":null,"created":"1449175408","gmt_created":"2015-12-03 20:43:28","changed":"1475894463","gmt_changed":"2016-10-08 02:41:03","alt":"Bone regeneration with stem cell scaffold","file":{"fid":"101292","name":"tyd39853.jpg","image_path":"\/sites\/default\/files\/images\/tyd39853_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tyd39853_0.jpg","mime":"image\/jpeg","size":405535,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tyd39853_0.jpg?itok=SU7f1o5P"}},"48926":{"id":"48926","type":"image","title":"Robert Guldberg bone regeneration","body":null,"created":"1449175408","gmt_created":"2015-12-03 20:43:28","changed":"1475894463","gmt_changed":"2016-10-08 02:41:03","alt":"Robert Guldberg bone regeneration","file":{"fid":"101293","name":"the39853.jpg","image_path":"\/sites\/default\/files\/images\/the39853_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/the39853_0.jpg","mime":"image\/jpeg","size":1050118,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/the39853_0.jpg?itok=crlQN6aN"}}},"media_ids":["48924","48925","48926"],"related_links":[{"url":"http:\/\/www.me.gatech.edu\/faculty\/guldberg.shtml","title":"Robert Guldberg"},{"url":"http:\/\/www.me.gatech.edu\/","title":"George W. Woodruff School of Mechanical Engineering"},{"url":"http:\/\/www.ibb.gatech.edu\/","title":"Petit Institute for Bioengineering and Bioscience"}],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"145","name":"Engineering"},{"id":"135","name":"Research"}],"keywords":[{"id":"8233","name":"amniotic fluid fetal stem cells"},{"id":"530","name":"bone"},{"id":"8227","name":"bone defect"},{"id":"8231","name":"Bone Marrow Derived Stem Cells"},{"id":"8226","name":"Bone Regeneration"},{"id":"8225","name":"Bone Repair"},{"id":"8232","name":"fetal stem cells"},{"id":"6891","name":"fluorescence"},{"id":"8230","name":"Mesenchymal Stem Cells"},{"id":"8228","name":"Orthopedics"},{"id":"8229","name":"polymer scaffold"},{"id":"2363","name":"quantum dots"},{"id":"1489","name":"Regenerative Medicine"},{"id":"167413","name":"Stem Cell"},{"id":"167139","name":"Stem Cell Research"},{"id":"167130","name":"Stem Cells"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EAbby Vogel\u003C\/strong\u003E\u003Cbr \/\u003EResearch News and Publications\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=avogel6\u0022\u003EContact Abby Vogel\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-3364\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["avogel@gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"45990":{"#nid":"45990","#data":{"type":"news","title":"New Institute of Bioengineering and Bioscience Director Named","body":[{"value":"\u003Cp\u003EAfter the completion of a nationwide search, Mechanical Engineering Professor Robert Guldberg has been named the new director of The Parker H. Petit Institute for Bioengineering and Bioscience (IBB) at the Georgia Institute of Technology.\u003C\/p\u003E\n\u003Cp\u003EGuldberg, who currently serves as IBB associate director, will assume duties as director on November 1.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022We\u0027re thrilled that Bob Guldberg has accepted this appointment,\u0022 said Senior Vice Provost for Research and Innovation Mark Allen. \u0022We had an enormous amount of interest and we attracted candidates of the highest caliber. He has thorough grounding in IBB and a great understanding of where it needs to go strategically in the next few years.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EGuldberg first joined the faculty ranks at Georgia Tech in 1996, serving both in IBB and the George W. Woodruff School of Mechanical Engineering.  He was appointed associate director of IBB in 2004.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022It is a great honor to be asked to serve as the next director of the Parker H. Petit Institute for Bioengineering and Bioscience,\u0022 said Guldberg. \u0022IBB\u0027s original mission when it was launched in 1995 was to be a vehicle for accelerating Georgia Tech\u0027s move into bio-related research.  This was an incredibly successful experiment made possible by the generous support of alumnus Pete Petit and the vision and dedicated efforts of IBB\u0027s founding director Bob Nerem and other leaders on campus.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EWhen first launched in 1995, the mission of IBB was to create an awareness of bioengineering and bioscience on the Georgia Tech campus. With the Institute now fully established, Guldberg said IBB is now \u0022positioned to have an even greater impact by serving as the heart of the broader Georgia Tech bioscience and bioengineering community and an international model for interdisciplinary research and education.\u0022\u003C\/p\u003E\n\u003Cp\u003EGuldberg succeeds Mechanical Engineering Professor Robert Nerem in the role of director. Nerem has served in this leadership role at IBB since its inception. Nerem will continue contributing to promising research goals, along with fostering Georgia Tech\u0027s evolving relationship with Emory University in the field of bioengineering.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022I believe Bob [Guldberg] has the right set of skills to take the Petit Institute to the next level,\u0022 said Nerem. \u0022He certainly will have my full support.\u0022\n\u003C\/p\u003E\n\u003Cp\u003E\u0022As for me, I will turn my attention and energies to continuing to build our regenerative medicine research program through our joint Georgia Tech\/Emory Center (GTEC).  This includes expanding our efforts in stem cell technology.  I also hope to help build further bridges between Georgia Tech and Emory University, as I believe Emory will in the future become an even more important partner with Georgia Tech.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EGuldberg received his undergraduate degree in mechanical engineering, his masters in bioengineering\/mechanical engineering and a doctorate in mechanical engineering from the University of Michigan. \n\u003C\/p\u003E\n\u003Cp\u003EThe rich promise that IBB poses in such areas as regenerative medicine, stem cell research and cancer fighting drugs has Guldberg enthused about the future of the Institute and the research that develops.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022Through leadership in addressing the challenges of translational research in addition to new collaborative programs and facilities, IBB will bring scientists and engineers together to work towards creative solutions to important scientific and societal problems,\u0022 Guldberg said. \u0022This is a great opportunity and I am tremendously excited to start this new chapter in the life of IBB.\u0022\u003C\/p\u003E\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Mechanical Engineering Professor Robert Guldberg has been named the new director of the Parker H. Petit Institute for Bioengineering and Bioscience.","format":"limited_html"}],"field_summary_sentence":[{"value":"Guldberg succeeds Nerem at helm of IBB"}],"uid":"27191","created_gmt":"2009-10-16 00:00:00","changed_gmt":"2016-10-08 03:03:09","author":"Robert Nesmith","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2009-10-16T00:00:00-04:00","iso_date":"2009-10-16T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"46034":{"id":"46034","type":"image","title":"Professor Robert Guldberg","body":null,"created":"1449174347","gmt_created":"2015-12-03 20:25:47","changed":"1475894409","gmt_changed":"2016-10-08 02:40:09","alt":"Professor Robert Guldberg","file":{"fid":"190087","name":"tss72660.jpg","image_path":"\/sites\/default\/files\/images\/tss72660_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tss72660_0.jpg","mime":"image\/jpeg","size":112193,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tss72660_0.jpg?itok=MTvUGTGG"}},"45992":{"id":"45992","type":"image","title":"Mechanical Engineering Professor Robert Nerem","body":null,"created":"1449174347","gmt_created":"2015-12-03 20:25:47","changed":"1475894409","gmt_changed":"2016-10-08 02:40:09","alt":"Mechanical Engineering Professor Robert Nerem","file":{"fid":"190086","name":"tax29428.jpg","image_path":"\/sites\/default\/files\/images\/tax29428_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tax29428_0.jpg","mime":"image\/jpeg","size":105192,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tax29428_0.jpg?itok=0DKc1Q8D"}}},"media_ids":["46034","45992"],"related_links":[{"url":"http:\/\/www.ibb.gatech.edu\/","title":"Petit Institute for Bioengineering and Bioscience"},{"url":"http:\/\/www.me.gatech.edu\/faculty\/guldberg.shtml","title":"Robert Guldberg"},{"url":"http:\/\/www.me.gatech.edu\/faculty\/nerem.shtml","title":"Robert Nerem"}],"groups":[{"id":"1183","name":"Home"}],"categories":[{"id":"135","name":"Research"}],"keywords":[{"id":"6973","name":"Guldberg"},{"id":"248","name":"IBB"},{"id":"1516","name":"Nerem"},{"id":"901","name":"Parker H. Petit"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EDon Fernandez\u003C\/strong\u003E\u003Cbr \/\u003EMarketing and Communications\u003Cbr \/\u003E\u003Ca href=\u0022mailto:don.fernandez@comm.gatech.edu\u0022\u003EContact Don Fernandez\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-6016\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["don.fernandez@comm.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"56406":{"#nid":"56406","#data":{"type":"news","title":"Labs report progress in regrowing bones","body":[{"value":"\u003Cp\u003EATLANTA \u2014 As military doctors in Iraq and Afghanistan have seen more horrific injuries involving skin, nerve, vascular and bone losses from explosions, they have tried to think of what more could be done for the victims besides bandaging things up and hoping for the best.\n\u003C\/p\u003E\n\u003Cp\u003EMaybe they could regrow the tissue: Grow the cartilage, grow the blood vessels, grow the nerves and even grow the bone. \n\u003C\/p\u003E\n\u003Cp\u003E\u003Ca href=\u0027http:\/\/www.armytimes.com\/news\/2009\/10\/marine_bone_101109w\/\u0027\u003EView full article\u003C\/a\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"ATLANTA \u2014 As military doctors in Iraq and Afghanistan have seen more horrific injuries involving skin, nerve, vascular and bone losses from explosions, they have tried to think of what more could be done for the victims besides bandaging things up and hoping for the best.","format":"limited_html"}],"field_summary_sentence":[{"value":"Labs report progress in regrowing bones"}],"uid":"27224","created_gmt":"2009-10-12 00:00:00","changed_gmt":"2016-10-08 03:06:06","author":"Megan McDevitt","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2009-10-12T00:00:00-04:00","iso_date":"2009-10-12T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"134","name":"Student and Faculty"}],"keywords":[{"id":"535","name":"boyan"},{"id":"6973","name":"Guldberg"},{"id":"9524","name":"orthopedic"},{"id":"167413","name":"Stem Cell"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EMegan McDevitt\u003C\/strong\u003E\u003Cbr \/\u003EIBB\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=mm504\u0022\u003EContact Megan McDevitt\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-7001\u003C\/strong\u003E","format":"limited_html"}],"email":["megan.mcdevitt@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"56436":{"#nid":"56436","#data":{"type":"news","title":"GTEC Celebrates Success - Renews Commitment to Regenerative Medicine","body":[{"value":"\u003Cp\u003EGeorgia Tech and Emory Celebrate Success and Renew Their Commitment to Regenerative Medicine \n\u003C\/p\u003E\n\u003Cp\u003EJanuary 13, 2009.  The Georgia Tech Emory Center for the Engineering of Living Tissues (GTEC), a National Science Foundation Engineering Research Center, celebrated its tenth year of innovative research. When founded in 1998, GTEC\u0027s focus was on replacing tissues or growing cell-based substitutes outside the body for implantation into the body. As GTEC has evolved over the last decade, its approach has broadened from a focus on tissue engineering to one that includes tissue regeneration.  \u003C\/p\u003E\n\u003Cp\u003ENow, a decade after the $25 million National Science Foundation award, GTEC is internationally recognized for its strengths and novel applications in the emerging field of Regenerative Medicine.  The center\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"January 13, 2009.  The Georgia Tech Emory Center for the Engineering of Living Tissues (GTEC), a National Science Foundation Engineering Research Center, celebrated its tenth year of innovative research. When founded in 1998, GTEC\u0027s focus was on replacing tissues or growing cell-based substitutes outside the body for implantation into the body. As GTEC has evolved over the last decade, its approach has broadened from a focus on tissue engineering to one that includes tissue regeneration.","format":"limited_html"}],"field_summary_sentence":[{"value":"GTEC Celebrates Success - Renews Commitment to Regenerative Med"}],"uid":"27224","created_gmt":"2009-01-26 01:00:00","changed_gmt":"2016-10-08 03:06:06","author":"Megan McDevitt","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2009-01-26T00:00:00-05:00","iso_date":"2009-01-26T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"56437":{"id":"56437","type":"image","title":"GTEC\\\u0027s Impact on State","body":null,"created":"1449175629","gmt_created":"2015-12-03 20:47:09","changed":"1475894501","gmt_changed":"2016-10-08 02:41:41","alt":"GTEC\\\u0027s Impact on State","file":{"fid":"190471","name":"tkn90302.jpg","image_path":"\/sites\/default\/files\/images\/tkn90302_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tkn90302_0.jpg","mime":"image\/jpeg","size":44700,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tkn90302_0.jpg?itok=qSlCTNMo"}},"56438":{"id":"56438","type":"image","title":"GTEC Celebration Dinner","body":null,"created":"1449175653","gmt_created":"2015-12-03 20:47:33","changed":"1475894501","gmt_changed":"2016-10-08 02:41:41","alt":"GTEC Celebration Dinner","file":{"fid":"190472","name":"tbm90302.jpg","image_path":"\/sites\/default\/files\/images\/tbm90302_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tbm90302_0.jpg","mime":"image\/jpeg","size":71285,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tbm90302_0.jpg?itok=iVv8YOXI"}}},"media_ids":["56437","56438"],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"130","name":"Alumni"},{"id":"129","name":"Institute and Campus"},{"id":"140","name":"Cancer Research"},{"id":"132","name":"Institute Leadership"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"},{"id":"150","name":"Physics and Physical Sciences"}],"keywords":[{"id":"247","name":"Emory"},{"id":"109","name":"Georgia Tech"},{"id":"1487","name":"GTEC"},{"id":"1489","name":"Regenerative Medicine"},{"id":"167130","name":"Stem Cells"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EMegan McDevitt\u003C\/strong\u003E\u003Cbr \/\u003EIBB\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=mm504\u0022\u003EContact Megan McDevitt\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-7001\u003C\/strong\u003E","format":"limited_html"}],"email":["megan.mcdevitt@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"56393":{"#nid":"56393","#data":{"type":"news","title":"Non-invasive tracking of nanocarrier distribution in tumors","body":[{"value":"\u003Cp\u003ENanocarrier-mediated chemotherapy has great promise in the treatment of cancer due to its ability to prolong the blood plasma half-life of the encapsulated chemotherapeutic and to selectively accumulate in tumors. However, in spite of important advances in the development of nano-chemotherapeutics, systemic chemotherapy is not the treatment of choice for malignant brain tumors, primarily due to the toxicity caused to non-tumor tissue. Therefore, novel techniques are required to understand and improve the drug availability at the tumor site while reducing harmful side effects. Nano-chemotherapeutics are able to accumulate at the tumor lesion due to the prolonged circulation of the nanocarrier and presence of abnormal leaky vasculature at the tumor site via the enhanced permeation and retention effect (EPR). \u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Nanocarrier-mediated chemotherapy has great promise in the treatment of cancer due to its ability to prolong the blood plasma half-life of the encapsulated chemotherapeutic and to selectively accumulate in tumors. However, in spite of important advances in the development of nano-chemotherapeutics, systemic chemotherapy is not the treatment of choice for malignant brain tumors, primarily due to the toxicity caused to non-tumor tissue. Therefore, novel techniques are required to understand and improve the drug availability at the tumor site while reducing harmful side effects. Nano-chemotherapeutics are able to accumulate at the tumor lesion due to the prolonged circulation of the nanocarrier and presence of abnormal leaky vasculature at the tumor site via the enhanced permeation and retention effect (EPR).","format":"limited_html"}],"field_summary_sentence":[{"value":"Non-invasive tracking of nanocarrier distribution in tumors"}],"uid":"27224","created_gmt":"2008-07-03 00:00:00","changed_gmt":"2016-10-08 03:06:06","author":"Megan McDevitt","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2008-07-03T00:00:00-04:00","iso_date":"2008-07-03T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/nanotechweb.org\/cws\/article\/lab\/34875","title":"Read Full Story"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"140","name":"Cancer Research"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"}],"keywords":[{"id":"9492","name":"bellamkonda"},{"id":"2286","name":"nano"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EMegan McDevitt\u003C\/strong\u003E\u003Cbr \/\u003EIBB\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=mm504\u0022\u003EContact Megan McDevitt\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-7001\u003C\/strong\u003E","format":"limited_html"}],"email":["megan.mcdevitt@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"56402":{"#nid":"56402","#data":{"type":"news","title":"McDevitt Research Highlighted in Nature Materials","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003E\u0022Materials in a Cellular World\u0022\n\u003C\/strong\u003E\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EBiological factors are not the only influence on stem-cell behaviour\u003C\/strong\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Following his presentation at the World Biomaterials Congress in Amsterdam in May 2008, Todd McDevitt, PhD, research is highlighted in Nature Materials Journal.  \u0022Materials in a Cellular World\u0022","format":"limited_html"}],"field_summary_sentence":[{"value":"McDevitt Research Highlighted in Nature Materials"}],"uid":"27195","created_gmt":"2008-08-28 00:00:00","changed_gmt":"2016-10-08 03:06:06","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2008-08-01T00:00:00-04:00","iso_date":"2008-08-01T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"140","name":"Cancer Research"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"135","name":"Research"}],"keywords":[{"id":"3024","name":"biomaterials"},{"id":"6217","name":"McDevitt"},{"id":"9518","name":"Nature Materials"},{"id":"1489","name":"Regenerative Medicine"},{"id":"167413","name":"Stem Cell"},{"id":"4891","name":"Tissue Engineering"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EColly Mitchell\u003C\/strong\u003E\u003Cbr \/\u003EParker H. Petit Institute for Bioengineering and Bioscience\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=cmitchell6\u0022\u003EContact Colly Mitchell\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-5982\u003C\/strong\u003E","format":"limited_html"}],"email":["colly.mitchell@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"56373":{"#nid":"56373","#data":{"type":"news","title":"Nanocarriers for Chemotherapy","body":[{"value":"\u003Cp\u003EVisit: \u003Ca href=\u0027http:\/\/nanotechweb.org\/articles\/journal\/6\/9\/4\/1 \u0027\u003Ehttp:\/\/nanotechweb.org\/articles\/journal\/6\/9\/4\/1 \u003C\/a\u003E\n\u003C\/p\u003E\n\u003Cp\u003ELiposomal nanocarriers coated with polyethylene glycol have been extensively investigated as chemotherapeutic delivery vehicles particularly due to their prolonged circulation in the bloodstream. Tumor blood vessels are inherently\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Liposomal nanocarriers coated with polyethylene glycol have been extensively investigated as chemotherapeutic delivery vehicles particularly due to their prolonged circulation in the bloodstream. Tumor blood vessels are inherently","format":"limited_html"}],"field_summary_sentence":[{"value":"Nanocarriers for Chemotherapy"}],"uid":"27224","created_gmt":"2007-09-13 00:00:00","changed_gmt":"2016-10-08 03:06:01","author":"Megan McDevitt","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2007-09-13T00:00:00-04:00","iso_date":"2007-09-13T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"134","name":"Student and Faculty"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"}],"keywords":[{"id":"9492","name":"bellamkonda"},{"id":"107","name":"Nanotechnology"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EMegan McDevitt\u003C\/strong\u003E\u003Cbr \/\u003EIBB\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=mm504\u0022\u003EContact Megan McDevitt\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-7001\u003C\/strong\u003E","format":"limited_html"}],"email":["megan.mcdevitt@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}