{"134971":{"#nid":"134971","#data":{"type":"news","title":"Georgia Tech Startup Secures Department of Defense Funding for Development of Cell Delivery Technology","body":[{"value":"\u003Cp\u003ECell-based therapies have yet to reach their full potential in repairing damaged tissue because of the hostile environment the cells face once injected into the body. A patient\u2019s inflammatory response normally causes the majority of these therapeutic cells to die or migrate away from the area in need of repair.\u003C\/p\u003E\u003Cp\u003ETo address this problem, a startup company based on technology developed at the Georgia Institute of Technology is creating an efficient, safe and repeatable delivery method that protects cells from death and migration from the treatment site. Using microbead technology developed in the \u003Ca href=\u0022http:\/\/www.bme.gatech.edu\/\u0022 target=\u0022_blank\u0022\u003EWallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University\u003C\/a\u003E, \u003Ca href=\u0022http:\/\/www.spheringenics.com\/\u0022 target=\u0022_blank\u0022\u003ESpherIngenics\u003C\/a\u003E is producing protective capsules for the delivery of cell-based therapies.\u003C\/p\u003E\u003Cp\u003ESupported by a broad range of Georgia Tech initiatives, the company recently received a two-year $730,000 Phase II Small Business Innovation Research (SBIR) grant from the U.S. Department of Defense to continue development of the technology.\u003C\/p\u003E\u003Cp\u003E\u201cWhen damaged tissue is being repaired by a cell-based therapy, our microbead technology ensures that cells travel to and remain in the targeted area while maintaining continued viability,\u201d said SpherIngenics CEO \u003Ca href=\u0022http:\/\/www.bme.gatech.edu\/facultystaff\/faculty_record.php?id=107\u0022 target=\u0022_blank\u0022\u003EFranklin Bost\u003C\/a\u003E, who is also a professor in the Coulter Department. \u201cThis technology has the potential to reduce the cost of treatment by eliminating the need for multiple therapeutic procedures.\u201d\u003C\/p\u003E\u003Cp\u003EBost and Coulter Department Professors \u003Ca href=\u0022http:\/\/www.bme.gatech.edu\/facultystaff\/faculty_record.php?id=48\u0022 target=\u0022_blank\u0022\u003EBarbara Boyan\u003C\/a\u003E and Zvi Schwartz founded the company in 2007. They worked with the Georgia Tech Research Corporation to license five patents from Boyan\u2019s lab for technology originally developed in the Georgia Tech\/Emory Center for the Engineering of Living Tissue (GTEC), which was funded by a grant from the National Science Foundation. Then they secured $450,000, which included a Phase I SBIR grant from the U.S. Department of Defense and grants from the Georgia Research Alliance and the Coulter Foundation.\u003C\/p\u003E\u003Cp\u003EDuring Phase I of the SBIR grant, the researchers confirmed that as many as 250 human adult stem cells could remain viable in culture if they were encapsulated in a 200-micron-diameter bead made of natural algae materials and that they could release factors that enhance tissue regeneration.\u003C\/p\u003E\u003Cp\u003E\u201cFor the Phase II SBIR grant, we\u2019re going to examine whether delivering microbeads full of stem cells can enhance cartilage repair and regeneration of craniofacial defects in an animal model,\u201d said Boyan, who is the company\u2019s chief scientific officer. Boyan is also the associate dean for research and innovation in the Georgia Tech College of Engineering, the Price Gilbert, Jr. Chair in Tissue Engineering at Georgia Tech, and a Georgia Research Alliance Eminent Scholar.\u003C\/p\u003E\u003Cp\u003EThe company will perform this research in its laboratory space located in the \u003Ca href=\u0022http:\/\/atdc.org\/\u0022 target=\u0022_blank\u0022\u003EAdvanced Technology Development Center\u003C\/a\u003E (ATDC) biosciences incubator.\u003C\/p\u003E\u003Cp\u003EThe company\u2019s ultimate goal is to commercialize the microbead technology for use in hospitals and by cell therapy companies. To help reach this goal, a group of students wrote a business plan for SpherIngenics last year through the Georgia Tech Scheller College of Business Technological Innovation: Generating Economic Results (\u003Ca href=\u0022http:\/\/tiger.gatech.edu\/\u0022 target=\u0022_blank\u0022\u003ETI:GER\u003C\/a\u003E) program.\u003C\/p\u003E\u003Cp\u003EThe team -- which included Coulter Department doctoral student Christopher Lee, Georgia Tech MBA students Chris Palazzola and Eric Diersen, and Emory University law students Bryan Stewart and Natalie Dana -- won third place in the 2011 Georgia Tech Business Plan Competition. The competition, while largely an education experience, provided students an opportunity to develop their venture ideas and present them to a panel of highly experienced judges in the venture capital, technology transfer and legal fields.\u003C\/p\u003E\u003Cp\u003E\u201cThe TI:GER team\u2019s business plan helped us learn about where the market for our technology is right now and where it is going in the future, which is extremely valuable knowledge as we work toward determining the most promising pathway to market,\u201d said Bost.\u003C\/p\u003E\u003Cp\u003EAdditional members of the company include Anthony Nicolini, the principal investigator on the Phase II SBIR grant, and Joseph Williams, clinical director of craniofacial plastic surgery at Children\u2019s Healthcare of Atlanta at Scottish Rite and clinical assistant professor in the Department of Plastic and Reconstructive Surgery at Emory University.\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003EResearch reported in this publication was supported by the U.S. Army Medical Research and Materiel Command under award numbers W81XWH-07-1-0219 and W81XWH-11-C-0071. The content is solely the responsibility of the principal investigators and does not necessarily represent the official views of the U.S. Government.\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E Georgia Institute of Technology\u003Cbr \/\u003E 75 Fifth Street, N.W., Suite 314\u003Cbr \/\u003E Atlanta, Georgia 30308 USA\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EMedia Relations Contacts:\u003C\/strong\u003E Abby Robinson (abby@innovate.gatech.edu; 404-385-3364) or John Toon (jtoon@gatech.edu; 404-894-6986)\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EWriter: \u003C\/strong\u003EAbby Robinson\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EGeorgia Tech startup SpherIngenics is using microbead technology to produce protective capsules for the delivery of cell-based therapies. The technology provides an efficient, safe and repeatable delivery method that protects cells from death and migration from the treatment site.\u0026nbsp;\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Georgia Tech cell delivery startup SpherIngenics secures defense funding."}],"uid":"27206","created_gmt":"2012-06-13 08:22:53","changed_gmt":"2016-10-08 03:12:22","author":"Abby Vogel Robinson","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2012-06-13T00:00:00-04:00","iso_date":"2012-06-13T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"134951":{"id":"134951","type":"image","title":"SpherIngenics microbeads","body":null,"created":"1449178671","gmt_created":"2015-12-03 21:37:51","changed":"1475894763","gmt_changed":"2016-10-08 02:46:03","alt":"SpherIngenics microbeads","file":{"fid":"194777","name":"spheringenics_microbeads.jpg","image_path":"\/sites\/default\/files\/images\/spheringenics_microbeads_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/spheringenics_microbeads_0.jpg","mime":"image\/jpeg","size":107104,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/spheringenics_microbeads_0.jpg?itok=H9YnVwp1"}}},"media_ids":["134951"],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"139","name":"Business"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"147","name":"Military Technology"},{"id":"135","name":"Research"}],"keywords":[{"id":"9548","name":"Barbara Boyan"},{"id":"35801","name":"Cartilage Repair"},{"id":"35791","name":"cell delivery"},{"id":"9534","name":"cell therapy"},{"id":"594","name":"college of engineering"},{"id":"35821","name":"cranial defect regeneration"},{"id":"11533","name":"Department of Biomedical Engineering"},{"id":"8246","name":"Department of Defense"},{"id":"12154","name":"Franklin Bost"},{"id":"35781","name":"Microbead"},{"id":"167833","name":"SBIR"},{"id":"169504","name":"spheringenics"},{"id":"166973","name":"startup"},{"id":"167413","name":"Stem Cell"},{"id":"35771","name":"Zvi Schwartz"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EAbby Robinson\u003Cbr \/\u003E Research News and Publications\u003Cbr \/\u003E \u003Ca href=\u0022mailto:abby@innovate.gatech.edu\u0022\u003Eabby@innovate.gatech.edu\u003C\/a\u003E\u003Cbr \/\u003E 404-385-3364\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"123171":{"#nid":"123171","#data":{"type":"news","title":"Shean Phelps Named Medical Director for the Translational Research Institute for Biomedical Engineering and Science (TRIBES)","body":[{"value":"\u003Cp\u003EShean Phelps, MD, MPH, FAAFP, has been named Medical Director for the Translational Research Institute for Biomedical Engineering and Science (TRIBES). In this role, he is responsible for providing key subject matter expertise to the development, execution and communication of TRIBES\u2019 scientific\/medical evidence plan.\u003C\/p\u003E\u003Cp\u003EIn addition, Dr. Phelps provides clinical input into safety and regulatory interactions and assists with the development of global collaborations that integrate broad medical, scientific, and commercial concepts into the program. These efforts are designed to shepherd the transition of viable ideas into useable products across and between the fields of medicine, technology and science.\u003C\/p\u003E\u003Cp\u003E\u201cWe are excited to have someone of Dr. Phelps\u2019 broad clinical expertise as part of our leadership team\u201d said Barbara Boyan, Executive Director of TRIBES and the Price Gilbert, Jr. Chair in Tissue Engineering in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory and Associate Dean for Research and Innovation for Georgia Tech\u2019s College of Engineering.\u003C\/p\u003E\u003Cp\u003EIn addition to his role as TRIBES Medical Director, Dr. Phelps serves as the Director of Health Systems Technology Research and Development at the Georgia Tech Research Institute where he manages and facilitates health-related technological synergies internally and externally.\u003C\/p\u003E\u003Cp\u003EDr. Phelps retired in March 2011 from the U. S. Army with over 30 years of total active federal service. He started in the military as a Special Forces Senior Non-Commissioned Officer. \u0026nbsp;Following his commission, he completed medical school and residency and retired as a Lieutenant Colonel in the Medical Corps.\u0026nbsp; His duties included planning, supporting, and\/or directing numerous Department of Defense research and development projects totaling over $150 million.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EWidely regarded as an expert on a variety of special operations\/operational medicine, injury biomechanics and wilderness medicine topics, he currently focuses on research into the cause, prevention, and development of applied solutions to human injury. He is certified as both a Senior U.S. Army and U.S. Navy Flight Surgeon\/Aerospace Medicine physician, and is a distinguished Fellow of the American Academy of Family Physicians.\u003C\/p\u003E\u003Cp\u003EThe Translational Research Institute for Biomedical Engineering and Science (TRIBES) links biomedical research and educational activities at Georgia Tech with key medical institutions and organizations for the benefit of diagnosis and treatment of patients in the healthcare system. TRIBES provides critical capabilities to pre-commercial engineering development activities for the license and transition of technology into industry.\u003C\/p\u003E\u003Cp\u003ETRIBES is part of the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University and includes three centers directed by Boyan \u2013 the Center for Advanced Bioengineering for Soldier Survivability, the Center for Pediatric Healthcare Technology Innovation and the Atlanta Pediatric Device Consortium.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EShean Phelps, MD, MPH, FAAFP, has been named Medical Director for the Translational Research Institute for Biomedical Engineering and Science (TRIBES). \u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":"","uid":"27182","created_gmt":"2012-04-10 14:01:01","changed_gmt":"2016-10-08 03:12:00","author":"Adrianne Proeller","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2012-04-10T00:00:00-04:00","iso_date":"2012-04-10T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"123161":{"id":"123161","type":"image","title":"Shean Phelps","body":null,"created":"1449178582","gmt_created":"2015-12-03 21:36:22","changed":"1475894743","gmt_changed":"2016-10-08 02:45:43","alt":"Shean Phelps","file":{"fid":"194424","name":"phelps_headshot.jpg","image_path":"\/sites\/default\/files\/images\/phelps_headshot_1.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/phelps_headshot_1.jpg","mime":"image\/jpeg","size":141965,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/phelps_headshot_1.jpg?itok=d1Z6_sG5"}}},"media_ids":["123161"],"related_links":[{"url":"http:\/\/www.tribes.gatech.edu\/welcome","title":"TRIBES"}],"groups":[{"id":"1254","name":"Wallace H. Coulter Dept. of Biomedical Engineering"}],"categories":[],"keywords":[{"id":"9548","name":"Barbara Boyan"},{"id":"12147","name":"medical director"},{"id":"169000","name":"Shean Phelps"},{"id":"12418","name":"TRIBES"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":["adrianne.proeller@bme.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"68872":{"#nid":"68872","#data":{"type":"news","title":"Department of Defense Research Center Helps to Develop Products for Regenerative Medicine","body":[{"value":"\u003Cp\u003EThe Center for Advanced Bioengineering for Solider Survivability (CABSS), a funded Center of the Fort Detrick\u2019s Telemedicince and Advance Technology Research Center (TATRC), has developed 3 medical products which will be beneficial to wounded service members. The extensive research and development of these and other medical innovations are performed by CABSS research team under the direction of Dr. Barbara Boyan. The three innovative technologies highlighted in this news article include: microbeads for stem cell delivery, creation of a scaffold for composite defects, and an imaging system that better detects internal bleeding in wounded service members. \u003C\/p\u003E\u003Cp\u003ERELATED LINKS \u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022http:\/\/www.boyanlab.gatech.edu\/\u0022\u003Ehttp:\/\/www.boyanlab.gatech.edu\/\u003C\/a\u003E\u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022http:\/\/www.fredericknewspost.com\/sections\/news\/display.htm?StoryID=117923\u0022\u003Ehttp:\/\/www.fredericknewspost.com\/sections\/news\/display.htm?StoryID=117923\u003C\/a\u003E\u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022http:\/\/www.tatrc.org\/\u0022\u003Ehttp:\/\/www.tatrc.org\/\u003C\/a\u003E\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003ECABSS develops 3 medical products which will be beneficial to wounded service members. \u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"CABBS research featured in FrederickNewsPost.com"}],"uid":"15436","created_gmt":"2011-07-20 16:10:22","changed_gmt":"2016-10-08 03:09:48","author":"Automator","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-07-20T00:00:00-04:00","iso_date":"2011-07-20T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"68871":{"id":"68871","type":"image","title":"microbead","body":null,"created":"1449177214","gmt_created":"2015-12-03 21:13:34","changed":"1475894599","gmt_changed":"2016-10-08 02:43:19","alt":"microbead","file":{"fid":"192674","name":"117923_large.jpg","image_path":"\/sites\/default\/files\/images\/117923_large_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/117923_large_0.jpg","mime":"image\/jpeg","size":73697,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/117923_large_0.jpg?itok=lJDfLv7p"}}},"media_ids":["68871"],"related_links":[{"url":"http:\/\/www.tatrc.org\/","title":"Telemedicine and Advance Technology Research Center"},{"url":"http:\/\/www.boyanlab.gatech.edu\/","title":"Boyan \u0026 Schwartz Laboratory"},{"url":"http:\/\/www.fredericknewspost.com\/sections\/news\/display.htm?StoryID=117923","title":"CABSS research featured in FrederickNewPost.com"}],"groups":[{"id":"65426","name":"IBB Center - CABSS"}],"categories":[],"keywords":[{"id":"9548","name":"Barbara Boyan"},{"id":"9540","name":"Bioengineering and Bioscience"},{"id":"13703","name":"CABSS"},{"id":"13704","name":"New Devices"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EMegan Eckstein \u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"68873":{"#nid":"68873","#data":{"type":"news","title":"Nature Article Notes CABSS Efforts in The War on Drugs","body":[{"value":"\u003Cp\u003EDr. Boyan\u2019s and colleagues\u2019 research is notably recognized by the Nature Publishing Group in the article: \u201cThe real war on drugs\u201d, by Cassandra Willyard. The injuries sustained by soldiers and aid workers alike in third world countries require innovative medical device solutions. CABSS, funded by the Department of Defense, is helping to provide better medical care for soldiers who encounter traumatic bone and tissue wound injuries overseas on duty by researching stem cells for the use of healing wounds.\u0026nbsp; \u003C\/p\u003E\u003Cp\u003E\u0026nbsp;RELATED LINKS \u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022http:\/\/www.nature.com\/nm\/journal\/v16\/n9\/full\/nm0910-948.html\u0022\u003Ehttp:\/\/www.nature.com\/nm\/journal\/v16\/n9\/full\/nm0910-948.html\u003C\/a\u003E\u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022http:\/\/www.nature.com\/nm\/journal\/v16\/n9\/full\/nm0910-948.html\u0022\u003Ehttp:\/\/www.boyanlab.gatech.edu\u003C\/a\u003E \u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022http:\/\/www.nature.com\/\u0022\u003Ehttp:\/\/www.nature.com\/\u003C\/a\u003E\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"CABSS is an quintessential research center aiding to combat  \u0022The real war on drugs\u0022"}],"uid":"15436","created_gmt":"2011-07-20 16:38:53","changed_gmt":"2016-10-08 03:09:48","author":"Automator","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-07-20T00:00:00-04:00","iso_date":"2011-07-20T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"68880":{"id":"68880","type":"image","title":"War on Drugs","body":null,"created":"1449177214","gmt_created":"2015-12-03 21:13:34","changed":"1475894599","gmt_changed":"2016-10-08 02:43:19","alt":"War on Drugs","file":{"fid":"192676","name":"nm0910-948-i1.jpg","image_path":"\/sites\/default\/files\/images\/nm0910-948-i1_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/nm0910-948-i1_0.jpg","mime":"image\/jpeg","size":23525,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/nm0910-948-i1_0.jpg?itok=JCOHuuIy"}}},"media_ids":["68880"],"related_links":[{"url":"http:\/\/www.nature.com\/nm\/journal\/v16\/n9\/full\/nm0910-948.html","title":"Nature Article on CABSS"},{"url":"http:\/\/www.nature.com\/","title":"Nature.com"}],"groups":[{"id":"65426","name":"IBB Center - CABSS"}],"categories":[],"keywords":[{"id":"13705","name":"CABBS"},{"id":"13241","name":"college of engineering; biomedical; Barbara Boyan"},{"id":"2777","name":"drug development"},{"id":"13706","name":"Nature Publishing Group"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003ECassandra Willyard \u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"66544":{"#nid":"66544","#data":{"type":"news","title":"Engineers Control the Environment to Direct Stem Cell Differentiation","body":[{"value":"\u003Cp\u003EStem cell technologies have been proposed for cell-based diagnostics and regenerative medicine therapies. However, being able to make stem cells efficiently develop into a desired cell type -- such as muscle, skin, blood vessels, bone or neurons -- limits the clinical potential of these technologies.\u003C\/p\u003E\u003Cp\u003ENew research presented on June 16, 2011 at the annual meeting of the International Society for Stem Cell Research (ISSCR) shows that systematically controlling the local and global environments during stem cell development helps to effectively direct the process of differentiation. In the future, these findings could be used to develop manufacturing procedures for producing large quantities of stem cells for diagnostic and therapeutic applications. The research is sponsored by the National Science Foundation and the National Institutes of Health.\u003C\/p\u003E\u003Cp\u003E\u0022Stem cells don\u0027t make any decisions in isolation; their decisions are spatially and temporally directed by biochemical and mechanical cues in their environment,\u0022 said Todd McDevitt, director of the Stem Cell Engineering Center at Georgia Tech and an associate professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. \u0022We have designed systems that allow us to tightly control these properties during stem cell differentiation, but also give us the flexibility to introduce a new growth factor or shake the cells a little faster to see how changes like these affect the outcome.\u0022\u003C\/p\u003E\u003Cp\u003EThese systems can also be used to compare the suitability of specific stem cell types for a particular use.\u003C\/p\u003E\u003Cp\u003E\u0022We have developed several platforms that will allow us to conduct head-to-head studies with different kinds of stem cells to determine if one type of stem cell outperforms another type for a certain application,\u0022 said McDevitt, who is also a Petit Faculty Fellow in the Institute for Bioengineering and Bioscience at Georgia Tech.\u003C\/p\u003E\u003Cp\u003EMany laboratory growth methods allow stem cells to aggregate in three-dimensional clumps called \u0022embryoid bodies\u0022 during differentiation. McDevitt and biomedical engineering graduate student Andres Bratt-Leal incorporated biomaterial particles directly within these aggregates during their formation. They introduced microparticles made of gelatin, poly(lactic-co-glycolic acid) (PLGA) or agarose and tested their impact on the assembly, intercellular communication and morphogenesis of the stem cell aggregates under different conditions by varying the microsphere-to-cell ratio and the size of the microspheres.\u003C\/p\u003E\u003Cp\u003EThe researchers found that the presence of the biomaterials alone modulated embryoid body differentiation, but did not adversely affect cell viability. Compared to typical delivery methods, providing differentiation factors -- retinoic acid, bone morphogenetic protein 4 (BMP4) and vascular endothelial growth factor (VEGF) -- via microparticles induced changes in the gene and protein expression patterns of the aggregates.\u003C\/p\u003E\u003Cp\u003EBy including tiny magnetic particles into the embryoid bodies during formation, the researchers also found they could use a magnet to spatially control the location of an aggregate and its assembly with other aggregates. The magnetic particles remained entrapped within the aggregates for the duration of the experiments but did not adversely affect cell viability or differentiation.\u003C\/p\u003E\u003Cp\u003E\u0022With biomaterial and magnetic microparticles, we are beginning to be able to recreate the types of complex geometric patterns seen during early development, which require multiple cues at the same time and the ability to spatially and temporally control their local presentation,\u0022 noted McDevitt.\u003C\/p\u003E\u003Cp\u003EWhile microparticles can be used to control differentiation by regulating the local environment, other methods exist to control differentiation through the global environment. Experiments by McDevitt and biomedical engineering graduate student Melissa Kinney have demonstrated that modulating hydrodynamic conditions can dictate the morphology of cell aggregate formation and control the expression of differentiated phenotypic cell markers.\u003C\/p\u003E\u003Cp\u003E\u0022Because bioreactors typically impose hydrodynamic forces on cells to cultivate large volumes of cells at high density, our use of hydrodynamics to control cell fate decisions represents a novel, yet simple, principle that could be used in the future for the scalable efficient production of stem cells,\u0022 added McDevitt.\u003C\/p\u003E\u003Cp\u003ETechnologies capable of being directly integrated into bioprocessing systems will be the best choice for manufacturing large batches of stem cells, he noted. In the future, the development of multi-scale techniques that combine different levels of control -- both local and global -- to regulate stem cell differentiation may help the translation of stem cells into viable clinical therapies.\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003EThis project is supported by the National Science Foundation (NSF) (Award No. CBET 0651739) and the National Institutes of Health (NIH) (R01GM088291). The content is solely the responsibility of the principal investigator and does not necessarily represent the official views of the NSF or NIH.\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E Georgia Institute of Technology\u003Cbr \/\u003E 75 Fifth Street, N.W., Suite 314\u003Cbr \/\u003E Atlanta, Georgia 30308 USA\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EMedia Relations Contacts: \u003C\/strong\u003EAbby Robinson (abby@innovate.gatech.edu; 404-385-3364) or John Toon (jtoon@gatech.edu; 404-894-6986)\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EWriter: \u003C\/strong\u003EAbby Robinson\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003ENew research shows that systematically controlling the local and global environments during stem cell development helps to effectively direct their differentiation.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Controlling the environment during stem cell development matters."}],"uid":"27206","created_gmt":"2011-06-16 00:00:00","changed_gmt":"2016-10-08 03:08:53","author":"Abby Vogel Robinson","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-06-16T00:00:00-04:00","iso_date":"2011-06-16T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"66545":{"id":"66545","type":"image","title":"Todd McDevitt","body":null,"created":"1449177176","gmt_created":"2015-12-03 21:12:56","changed":"1475894592","gmt_changed":"2016-10-08 02:43:12"},"66546":{"id":"66546","type":"image","title":"Magnetic embryoid bodies","body":null,"created":"1449177176","gmt_created":"2015-12-03 21:12:56","changed":"1475894592","gmt_changed":"2016-10-08 02:43:12"},"66547":{"id":"66547","type":"image","title":"Shaking stem cells","body":null,"created":"1449177176","gmt_created":"2015-12-03 21:12:56","changed":"1475894592","gmt_changed":"2016-10-08 02:43:12"}},"media_ids":["66545","66546","66547"],"related_links":[{"url":"http:\/\/www.bme.gatech.edu\/facultystaff\/faculty_record.php?id=78","title":"Todd McDevitt"},{"url":"http:\/\/www.bme.gatech.edu\/","title":"Wallace H. Coulter Department of Biomedical Engineering"},{"url":"http:\/\/scec.gatech.edu\/","title":"Stem Cell Engineering Center"},{"url":"http:\/\/www.ibb.gatech.edu\/","title":"Petit Institute for Bioengineering and Bioscience"}],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"135","name":"Research"}],"keywords":[{"id":"594","name":"college of engineering"},{"id":"11533","name":"Department of Biomedical Engineering"},{"id":"13436","name":"embryoid bodies"},{"id":"7663","name":"magnetic particles"},{"id":"167413","name":"Stem Cell"},{"id":"171090","name":"Stem Cell Biology"},{"id":"171010","name":"Stem Cell Development"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EAbby Robinson\u003C\/strong\u003E\u003Cbr \/\u003EResearch News and Publications\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=avogel6\u0022\u003EContact Abby Robinson\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-3364\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["abby@innovate.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"66348":{"#nid":"66348","#data":{"type":"external_news","title":"CNN Video: Analyzing Stem Cell Research","body":[{"value":"\u003Cp\u003ECNN Video: Georgia Tech\u0027s, Todd McDevitt, analyzes new stem cell therapy, and the concerns surrounding it. View the segment at the link provided.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27349","created_gmt":"2011-06-01 13:12:40","changed_gmt":"2016-10-08 02:24:30","author":"Floyd Wood","boilerplate_text":"","field_publication":"","publication":"McMillan Street","field_article_url":"","publication_url":"http:\/\/www.cnn.com\/video\/data\/2.0\/video\/world\/2011\/05\/17\/analyzing.stem.cell.research.cnn.html","dateline":{"date":"2011-06-17T00:00:00-04:00","iso_date":"2011-06-17T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"134","name":"Student and Faculty"}],"keywords":[{"id":"13240","name":"Analyzing Stem Cell Research"},{"id":"248","name":"IBB"},{"id":"760","name":"Todd McDevitt"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"116041":{"#nid":"116041","#data":{"type":"news","title":"TI:GER\u00ae Team SpherIngenics Places in Competition for Stem Cell Technology spacer","body":[{"value":"\u003Cp\u003EThe Ti:GER team, SpherIngenics, won $2,000 in the Business Plan \ncompetion this past March. Chris Lee, a PhD candidate of the Boyan Lab \nalong with Chris Palazoola (MBA), Eric Diersen (MBA), Brian Stewart (JD)\n and Natalie Dana (JD) form part of this team presenting their \nencapsulated cell therapy technology to deliver stem cells more \nprecisely and effectively.\u0026nbsp; This technology was developed in the \nBoyan\/Schwartz Laboratory.\u003C\/p\u003E\u003Cp\u003EMore about this news: \u003Ca title=\u0022http:\/\/mgt.gatech.edu\/news_room\/news\/2011\/articles\/SpherIngenics.html\u0022 href=\u0022http:\/\/mgt.gatech.edu\/news_room\/news\/2011\/articles\/SpherIngenics.html\u0022\u003Ehttp:\/\/mgt.gatech.edu\/news_room\/news\/2011\/articles\/SpherIngenics.html\u003C\/a\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EThe Ti:GER team, SpherIngenics, won $2,000 in the Business Plan \ncompetion this past March. Chris Lee, a PhD candidate of the Boyan Lab \nalong with Chris Palazoola (MBA), Eric Diersen (MBA), Brian Stewart (JD)\n and Natalie Dana (JD) form part of this team presenting their \nencapsulated cell therapy technology to deliver stem cells more \nprecisely and effectively.\u0026nbsp; This technology was developed in the \nBoyan\/Schwartz Laboratory.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"SpherIngenics won third place in the 2011 Georgia Tech Business Plan Competition"}],"uid":"27414","created_gmt":"2012-03-12 10:17:41","changed_gmt":"2016-10-08 03:11:48","author":"Maribel Baker","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2011-03-31T00:00:00-04:00","iso_date":"2011-03-31T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"116051":{"id":"116051","type":"image","title":"Tiger Team SpherIngenics","body":null,"created":"1449178241","gmt_created":"2015-12-03 21:30:41","changed":"1475894736","gmt_changed":"2016-10-08 02:45:36","alt":"Tiger Team SpherIngenics","file":{"fid":"194234","name":"spheringenics_0.jpg","image_path":"\/sites\/default\/files\/images\/spheringenics_0_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/spheringenics_0_0.jpg","mime":"image\/jpeg","size":26918,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/spheringenics_0_0.jpg?itok=oJ8-YOZD"}}},"media_ids":["116051"],"groups":[{"id":"67773","name":"IBB Center - TRIBES"}],"categories":[{"id":"129","name":"Institute and Campus"}],"keywords":[{"id":"2983","name":"business plan competition"},{"id":"169504","name":"spheringenics"},{"id":"171191","name":"stem cell technology"},{"id":"26821","name":"tiger"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cem\u003E\u003Cstrong\u003EHope Wilson\u003C\/strong\u003E\u003C\/em\u003E\u003Cbr \/\u003EDirector of Communications\u003C\/p\u003E\u003Cp\u003E 404.385.0580\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u003Cbr \/\u003E\u003Ca href=\u0022mailto:hope.wilson@mgt.gatech.edu\u0022\u003Ehope.wilson@mgt.gatech.edu\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["hope.wilson@mgt.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"46312":{"#nid":"46312","#data":{"type":"news","title":"New Center Aims to Improve Recovery of Soldiers with Severe Injuries","body":[{"value":"\u003Cp\u003EWhen a soldier is wounded during combat, surgeons must focus on reducing infection and reconstructing damaged bone and tissues. Technologies that could improve the repair and regeneration processes are being developed in research laboratories across the country, but they are not being moved quickly enough into military trauma centers.\u003C\/p\u003E\n\u003Cp\u003EOrganizers of the recently established Georgia Tech Center for Advanced Bioengineering for Soldier Survivability want to change that.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022The goal of the center is to rapidly move new technologies from the laboratory to patients so that we can improve the quality of life for our veterans as they return from the wars the United States is fighting,\u0022 said center director Barbara Boyan, the Price Gilbert, Jr. Chair in Tissue Engineering at the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University.\n\u003C\/p\u003E\n\u003Cp\u003EThe center will leverage the expertise of Georgia Tech researchers in musculoskeletal biology and regenerative medicine to quickly move tools that are clinically valuable, safe and effective from laboratories to use in trauma centers. To reduce the amount of time from invention to clinical use, engineers and scientists in the center work in teams that include a clinician with experience in combat medical care and a medical device industry partner. \n\u003C\/p\u003E\n\u003Cp\u003ESupport for the center is provided by the Armed Forces Institute of Regenerative Medicine, the U.S. Army Institute of Surgical Research\u0027s Orthopedic Trauma Research Program, the U.S. Department of Defense and industry.\u003C\/p\u003E\n\u003Cp\u003EResearchers in the center will initially focus on ways to improve the healing of wounds, segmental bone defects and massive soft tissue defects. Traumatic injuries that affect the arms, legs, head and neck require technologies for treatment at the time of injury and in the ensuing days and months.  \n\u003C\/p\u003E\n\u003Cp\u003E\u0022These combat injuries are complicated to treat because they are large and typically infected, so even determining when a soldier should be treated for optimal recovery is a challenge,\u0022 said Boyan, who is also the associate dean for research in Georgia Tech\u0027s College of Engineering and a Georgia Research Alliance Eminent Scholar. \u0022It is not known whether a regenerative therapy will be most effective if used immediately following injury or at some later time after scar tissue has been established at the wound site.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EBy developing models that accurately reflect the complex aspects of injuries sustained by soldiers in combat, the researchers will be able to test assumptions about when to employ specific strategies and how to ensure their effectiveness. The models must also allow them to examine the use of technologies on both male and female patients, and on complex tissues that consist of nerves, a blood supply and multiple cell types.  \n\u003C\/p\u003E\n\u003Cp\u003E\u0022Since the processes of bone, vascular and neural formation are naturally linked during normal tissue development, growth and repair, our approach is to harness this knowledge by developing delivery strategies that present the right biologic cues in the right place at the right time to promote functional regeneration of multiple integrated tissues,\u0022 said associate director of the center Robert Guldberg, a professor in Georgia Tech\u0027s Woodruff School of Mechanical Engineering.\n\u003C\/p\u003E\n\u003Cp\u003ETo enhance tissue repair and regeneration following a traumatic injury, the researchers are focusing their efforts on stem cells. Even though stem cells have tremendous potential for repairing such defects, effective methods do not yet exist for delivering them to an injury site and of ensuring that they survive and remain at that site long enough to impact the regeneration process.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022Clinicians currently inject stem cells into a vein and hope that the cells will migrate to sites of injury and remain at those sites long enough to participate in the repair process. While some cells certainly do migrate to injury sites, the actual percentage is very small and those that arrive at the site do not remain to engraft with the host tissue,\u0022 explained Boyan.\u003C\/p\u003E\n\u003Cp\u003EThis limited effect may be the result of the injection process, according to Boyan, so researchers in the center are developing ways to protect the cells from damaging forces they might encounter when inserted into the body.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022Studies in our laboratory have shown that when stem cells are encapsulated in microbeads, they can be injected by needle without loss of cell viability and they remain at the injury site for at least two months,\u0022 said Boyan.\n\u003C\/p\u003E\n\u003Cp\u003EProtecting the cells during insertion is just the first step toward improved tissue repair. The researchers must also examine whether the stem cells will turn into cells typical of the implanted tissue and if they produce or should be paired with molecules that can enhance the healing of the implanted tissues.\n\u003C\/p\u003E\n\u003Cp\u003ECenter researchers are also investigating whether bone marrow-derived stem cells can be used in the body to heal large defects in bone and cartilage if they are inserted in fiber mesh scaffolds and silk sponges during a surgical procedure.\n\u003C\/p\u003E\n\u003Cp\u003EAdditional projects in the center include assessing tissue viability, preventing the growth of bone in the soft tissues of the body and improving pre-hospital care of orthopedic injuries. Since effective treatment of traumatic injuries is an important goal for the general public as well as the military population, the researchers also hope to adapt their technologies for use in hospitals.\n\u003C\/p\u003E\n\u003Cp\u003EOther researchers in the center include Ravi Bellamkonda, a professor in the Coulter Department; Andres Garcia, the Woodruff Faculty Fellow in the Woodruff School of Mechanical Engineering; Robert Taylor, a professor in the Coulter Department and Emory\u0027s Division of Cardiology; Zvi Schwartz, a visiting professor in the Coulter Department; and U.S. Army surgical medicine consultants Michael Yaszemski and David Cohen.\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E\nGeorgia Institute of Technology\u003Cbr \/\u003E\n75 Fifth Street, N.W., Suite 100\u003Cbr \/\u003E\nAtlanta, Georgia  30308  USA\n\u003C\/strong\u003E\u003C\/p\u003E\n\u003Cp\u003EMedia Relations Contacts: Abby Vogel (404-385-3364); E-mail: (\u003Ca href=\u0022mailto:avogel@gatech.edu\u0022\u003Eavogel@gatech.edu\u003C\/a\u003E) or John Toon (404-894-6986); E-mail: (\u003Ca href=\u0022mailto:jtoon@gatech.edu\u0022\u003Ejtoon@gatech.edu\u003C\/a\u003E).\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EWriter:\u003C\/strong\u003E Abby Vogel\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"Musculoskeletal Biology and Regenerative Medicine Expertise are Keys"}],"field_summary":[{"value":"The new Georgia Tech Center for Advanced Bioengineering for Soldier Survivability is working to quickly move tools that are clinically valuable, safe and effective from laboratories to use in military trauma centers.","format":"limited_html"}],"field_summary_sentence":[{"value":"New center aims to improve recovery of severely-injured soldiers"}],"uid":"27206","created_gmt":"2009-05-26 00:00:00","changed_gmt":"2016-10-08 03:03:14","author":"Abby Vogel Robinson","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2009-05-26T00:00:00-04:00","iso_date":"2009-05-26T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"46313":{"id":"46313","type":"image","title":"Barbara Boyan","body":null,"created":"1449174375","gmt_created":"2015-12-03 20:26:15","changed":"1475894416","gmt_changed":"2016-10-08 02:40:16","alt":"Barbara Boyan","file":{"fid":"101089","name":"toy61295.jpg","image_path":"\/sites\/default\/files\/images\/toy61295_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/toy61295_0.jpg","mime":"image\/jpeg","size":1083074,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/toy61295_0.jpg?itok=XMwONj2V"}},"46314":{"id":"46314","type":"image","title":"bone defect","body":null,"created":"1449174401","gmt_created":"2015-12-03 20:26:41","changed":"1475894416","gmt_changed":"2016-10-08 02:40:16","alt":"bone defect","file":{"fid":"101090","name":"tcq61295.jpg","image_path":"\/sites\/default\/files\/images\/tcq61295_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tcq61295_0.jpg","mime":"image\/jpeg","size":35753,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tcq61295_0.jpg?itok=fbnt2zCT"}},"46315":{"id":"46315","type":"image","title":"Robert Guldberg","body":null,"created":"1449174401","gmt_created":"2015-12-03 20:26:41","changed":"1475894416","gmt_changed":"2016-10-08 02:40:16","alt":"Robert Guldberg","file":{"fid":"101091","name":"tgx61295.jpg","image_path":"\/sites\/default\/files\/images\/tgx61295_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/tgx61295_0.jpg","mime":"image\/jpeg","size":1098693,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tgx61295_0.jpg?itok=RfWhTAre"}}},"media_ids":["46313","46314","46315"],"related_links":[{"url":"http:\/\/www.bme.gatech.edu\/facultystaff\/faculty_record.php?id=48","title":"Barbara Boyan"},{"url":"http:\/\/www.me.gatech.edu\/faculty\/guldberg.shtml","title":"Robert Guldberg"},{"url":"http:\/\/www.bme.gatech.edu\/","title":"Wallace H. Coulter Department of Biomedical Engineering"},{"url":"http:\/\/www.me.gatech.edu\/","title":"George W. Woodruff School of Mechanical Engineering"}],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"147","name":"Military Technology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"}],"keywords":[{"id":"534","name":"barbara"},{"id":"277","name":"Biology"},{"id":"530","name":"bone"},{"id":"535","name":"boyan"},{"id":"532","name":"cell"},{"id":"531","name":"defect"},{"id":"528","name":"device"},{"id":"537","name":"goldberg"},{"id":"521","name":"injury"},{"id":"527","name":"medical"},{"id":"524","name":"medicine"},{"id":"525","name":"military"},{"id":"522","name":"muskuloskeletal"},{"id":"523","name":"regenerative"},{"id":"536","name":"robert"},{"id":"170849","name":"soldier"},{"id":"167258","name":"STEM"},{"id":"533","name":"tissue"},{"id":"526","name":"trauma"},{"id":"529","name":"wound"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EAbby Vogel\u003C\/strong\u003E\u003Cbr \/\u003EResearch News and Publications\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=avogel6\u0022\u003EContact Abby Vogel\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-3364\u003C\/strong\u003E","format":"limited_html"}],"email":["avogel@gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}