{"666353":{"#nid":"666353","#data":{"type":"event","title":"Special Seminar: Prof. Kyle Biegasiewicz (Arizona State University)","body":[{"value":"\u003Cp\u003ETitle -\u0026nbsp;\u003Cstrong\u003EChemical and Enzymatic Strategies for Complex Molecule Synthesis\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EThe chemical synthesis of structurally and stereochemically complex molecules is a focal point of the pharmaceutical, agricultural, and materials industries.\u0026nbsp; To optimize the desired parameters affiliated with their syntheses (step, atom, redox economies), we rely heavily upon the discovery of catalysts that can accomplish early- and late-stage bond construction under mild conditions, broad functional group tolerance, and with little to no waste production.\u0026nbsp; This seminar will feature a combination of chemical and enzymatic strategies for achieving catalytic carbon-carbon (C-C) bond formation.\u0026nbsp; It will be divided into three parts including 1) the development of an organocatalytic hydroxymethylation protocol and its application in the total synthesis of the apoptosis inducer, (-)-rasfonin, 2) photoexcitation of flavoenzymes for stereoselective C-C bond formation, and 3) the development of a class of terpene cyclases using oxyanion hole catalysis in hydrolase enzymes.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Special Seminar - Guest - Kyle Biegasiewicz - Arizona State University"}],"uid":"36441","created_gmt":"2023-03-02 13:41:36","changed_gmt":"2023-03-10 21:29:06","author":"slawrence67","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2023-03-16T15:20:00-04:00","event_time_end":"2023-03-16T16:20:00-04:00","event_time_end_last":"2023-03-16T16:20:00-04:00","gmt_time_start":"2023-03-16 19:20:00","gmt_time_end":"2023-03-16 20:20:00","gmt_time_end_last":"2023-03-16 20:20:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"85951","name":"School of Chemistry and Biochemistry"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"78771","name":"Public"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}