{"68963":{"#nid":"68963","#data":{"type":"event","title":"GaP Seminar Series","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EHyewon Lee\u003C\/strong\u003E\u0026nbsp;- Advisor, Hang Lu, PhD\u003Cbr \/\u003E\u003Cstrong\u003E\u003Cem\u003E\u0022\u003C\/em\u003E\u003C\/strong\u003E\u003Cstrong\u003E\u003Cem\u003EQuantitative Screening of C. elegans using Microfluidic Devices and Adaptive Algorithm\u0022\u003C\/em\u003E\u003C\/strong\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EForward genetic screening is a powerful tool to identify components in pathways in model organisms such as the nematode C. elegans. We use a single-layer microlfuidic device and quantitative analysis to screen a large number of animals in a high-throughput manner. This technology allows us to identify rare mutants that are difficult to find by eye. In a screen, we found many mutants that act to regulate tryptophan hydroxylase.\u0026nbsp;\u003Cbr \/\u003E\u003Cstrong\u003E\u003Cbr \/\u003ECatera Wilder\u003C\/strong\u003E - Advisor, Manu Platt, PhD\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003E\u003Cem\u003E\u0022Fight\nfor the Niche: Invasive Breast Cancer Cells Influence Msc Differentiation and\nSurvival in a Co-Culture Model\u0022\u003C\/em\u003E\u003C\/strong\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EWhen metastatic tumors reach the bone marrow the cancer cells will alter the microenvironment to promote their survival. Studies have shown a link between increased fatty bone marrow and a risk of cancer. The protease cathepsin K is associated with adipocyte differentiation and is upregulated in cancer. We hypothesized that cancer cells are promoting adipogenesis using cathepsin remodeling of the ECM as a mechanism to alter the microenvironment.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cbr \/\u003EThe Graduate and Post-Doc (GaP) Seminar Series is a weekly event of research presentations by two graduate students or post-docs conducting bio-related research.\u0026nbsp; The series is organized and sponsored by the Parker H. Petit Institute for Bioengineering and Bioscience (IBB) with additional support from the Wallace H. Coulter Department of Biomedical Engineering. It is held every Wednesday at 12:00pm in IBB 1128 and refreshments are provided. If your research group or department would like to present at future seminars, please contact Manu Platt, PhD at\u0026nbsp;\u003Ca href=\u0022mailto:manu.platt@bme.gatech.edu\u0022\u003Emanu.platt@bme.gatech.edu\u003C\/a\u003E.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EHyewon Lee and Catera Wilder presenting\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Hyewon Lee and Catera Wilder presenting"}],"uid":"27195","created_gmt":"2011-07-27 09:36:04","changed_gmt":"2016-10-08 01:55:18","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-11-30T11:00:00-05:00","event_time_end":"2011-11-30T12:00:00-05:00","event_time_end_last":"2011-11-30T12:00:00-05:00","gmt_time_start":"2011-11-30 16:00:00","gmt_time_end":"2011-11-30 17:00:00","gmt_time_end_last":"2011-11-30 17:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"hg_media":{"65807":{"id":"65807","type":"image","title":"GaP Seminar Series","body":null,"created":"1449176884","gmt_created":"2015-12-03 21:08:04","changed":"1475894582","gmt_changed":"2016-10-08 02:43:02","alt":"GaP Seminar Series","file":{"fid":"192409","name":"GaP_Logo_-_square.png","image_path":"\/sites\/default\/files\/images\/GaP_Logo_-_square_0.png","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/GaP_Logo_-_square_0.png","mime":"image\/png","size":9759,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/GaP_Logo_-_square_0.png?itok=xFPLw_YI"}},"71276":{"id":"71276","type":"image","title":"Hyewon Lee","body":null,"created":"1449177367","gmt_created":"2015-12-03 21:16:07","changed":"1475894632","gmt_changed":"2016-10-08 02:43:52","alt":"Hyewon Lee","file":{"fid":"193505","name":"hyewon_lee.jpg","image_path":"\/sites\/default\/files\/images\/hyewon_lee_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/hyewon_lee_0.jpg","mime":"image\/jpeg","size":22574,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/hyewon_lee_0.jpg?itok=fatX8U6y"}},"73070":{"id":"73070","type":"image","title":"Catera Wilder","body":null,"created":"1449177979","gmt_created":"2015-12-03 21:26:19","changed":"1475894671","gmt_changed":"2016-10-08 02:44:31","alt":"Catera Wilder","file":{"fid":"193725","name":"wilderc.jpg","image_path":"\/sites\/default\/files\/images\/wilderc_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/wilderc_0.jpg","mime":"image\/jpeg","size":29779,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/wilderc_0.jpg?itok=hNnYInl_"}}},"media_ids":["65807","71276","73070"],"related_links":[{"url":"http:\/\/www.ibb.gatech.edu\/gap-seminar-series","title":"GaP Seminar Series Schedule"},{"url":"http:\/\/www.ibb.gatech.edu\/","title":"Petit Institute for Bioengineering and Bioscience"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"13776","name":"Catera Wilder"},{"id":"12813","name":"GaP Seminar"},{"id":"248","name":"IBB"},{"id":"167524","name":"Sharon Hamilton"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EManu Platt, PhD\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}