{"63926":{"#nid":"63926","#data":{"type":"event","title":"Bioengineering Seminar - Sarah Heilshorn, PhD - Stanford University","body":[{"value":"\u003Cp\u003EProtein-based polymeric materials are characterized by\nmulti-functionality, complex structural diversity, and bioactivity.\nUsing protein-based biomaterials may substantially increase the\nefficacy of regenerative medicine therapies by providing cell-protein\ninteractions that guide cell behavior. Several examples of\nprotein-based biomaterials design will be presented to highlight the\nimportance of independent control over biochemical and biomechanical\nproperties. Using recombinant protein technology, we have synthesized\nseveral families of block-co-peptide hydrogels that mimic critical\naspects of the natural extracellular matrix. A modular design strategy\nenables independent tuning of the initial elastic modulus, the density\nof cell adhesion ligands, and the rate of proteolytic remodeling. These\nbiomaterials can be designed to release multiple therapeutic peptides\nwith distinct spatial and temporal delivery profiles. Protein-based\nmaterials can also be used as templates to guide the synthesis of\ninorganic nanomaterials. Specifically, we are utilizing the protein\nclathrin, which has the ability to form multiple 2D and 3D\narchitectures, as a flexible template that can be functionalized at\nspecific sites using designed bi-functional peptides. These peptides\nserve as molecular bridges between binding sites on the clathrin\nprotein and inorganic materials including gold, titania, and cobalt\noxide. By generating a family of engineered peptides, we are developing\na flexible, modular system that will enable the rapid development of\nmultiple inorganic nanostructures from a single protein template\nmaterial.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EBioengineering Seminar Speaker, Sarah Heilshorn, PhD from Stanford University will be speaking on, \u0022Designing Multi-Functional Biopolymers Through Protein Engineering.\u0022\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Designing Multi-Functional Biopolymers Through Protein Engineering"}],"uid":"27224","created_gmt":"2011-01-27 15:44:22","changed_gmt":"2016-10-08 01:54:00","author":"Megan McDevitt","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-02-08T10:00:00-05:00","event_time_end":"2011-02-08T11:00:00-05:00","event_time_end_last":"2011-02-08T11:00:00-05:00","gmt_time_start":"2011-02-08 15:00:00","gmt_time_end":"2011-02-08 16:00:00","gmt_time_end_last":"2011-02-08 16:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"5983","name":"Bioengineering Seminar"},{"id":"248","name":"IBB"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EFaculty Host: Valeria Milam, PhD\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"68710":{"#nid":"68710","#data":{"type":"event","title":"2011 BIO Vendor Showcase","body":[{"value":"\u003Cp\u003EIBB, with the Bioengineering and Bioscience Unified Graduate Student group (BBUGS), will host its annual Vendor Showcase at Georgia Tech on Thursday, September 8, 2011 in the IBB atrium. 35+ plus companies will be on hand to display and demonstrate their equipment and research techniques thereby offering a great opportunity for faculty and staff to learn about new products as well.\u003C\/p\u003E\n\u003Cp\u003EDonated items by vendors will be raffled for attendees throughout the showcase.\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EVendor Information:\u003C\/strong\u003E\u003C\/p\u003E\n\u003Cp\u003EReservations are available now for exhibit tables for purchase by credit card: \u0026nbsp;\u003Ca href=\u0022https:\/\/epay.gatech.edu\/C20793_ustores\/web\/store_main.jsp?STOREID=55\u0022\u003EVendor Registration\u003C\/a\u003E\u003C\/p\u003E\u003Cp\u003EFirst floor tables only - $200 (35 available).\u003C\/p\u003E\n\u003Cp\u003EWe will not be using the seminar room as in years past. Food will be served throughout the event to maximize exposure. For companies that can donate an item to be raffled off, please note, these raffles will take place throughout the event.\u003C\/p\u003E\n\u003Cp\u003E\u003Cem\u003EThe Vendor must register and submit payment before reservation can be confirmed.\u003C\/em\u003E\u003C\/p\u003E\n\u003Cp\u003EThe following will be provided to vendor participants:\u003C\/p\u003E\n\u003Cp\u003E**Advertising and Marketing for the event\u003Cbr \/\u003E\n**4 ft. table - arranged alphabetically by company name\u003Cbr \/\u003E\n**free parking\u003Cbr \/\u003E\n**lunch\u003C\/p\u003E\n\u003Cp\u003EIf you have any additional questions, please contact \u003Ca href=\u0022mailto:colly.mitchell@ibb.gatech.edu\u0022\u003EColly Mitchell\u003C\/a\u003E\u003C\/p\u003E\n\u003Cp\u003ESpace is limited, so register today by visiting: \u0026nbsp;\u003Ca href=\u0022https:\/\/epay.gatech.edu\/C20793_ustores\/web\/store_main.jsp?STOREID=55\u0022\u003EVendor Registration\u003C\/a\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003E2011 BIO Vendor Showcase - Registration Open!\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Vendor registration open now!"}],"uid":"27195","created_gmt":"2011-07-06 11:01:38","changed_gmt":"2016-10-08 01:55:13","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-09-08T11:00:00-04:00","event_time_end":"2011-09-08T15:00:00-04:00","event_time_end_last":"2011-09-08T15:00:00-04:00","gmt_time_start":"2011-09-08 15:00:00","gmt_time_end":"2011-09-08 19:00:00","gmt_time_end_last":"2011-09-08 19:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/bbugs.gatech.edu\/","title":"BBUGS website"},{"url":"http:\/\/ibb.gatech.edu\/","title":"Parker H. Petit Institute for Bioengineering and Bioscience"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"4943","name":"BBUGS"},{"id":"248","name":"IBB"},{"id":"13596","name":"Vendor Showcase"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EColly Mitchell\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"69754":{"#nid":"69754","#data":{"type":"event","title":"2011 Biotech Career Fair","body":[{"value":"\u003Cp\u003EThe 7th Annual Georgia Tech Biotechnology Career Fair is currently being organized! \n\nLast year, over 250 students attended from all Georgia Tech departments and interacted with company representatives from over 25 companies. \u003Cbr \/\u003E\n\n\u003Cbr \/\u003EIn the days and weeks before the Career Fair, we will host panel discussions featuring Georgia Tech alumni and their industry experiences, corporate information sessions, and professional development seminars for both undergraduate and graduate students. We will also have a Student Resume Database that will be accessible exclusively to companies that have registered for the fair. \u003Cbr \/\u003E\u003Cbr \/\u003ECompanies also have the opportunity to sponsor one of these seminar events or to sponsor the entire fair! \n\nCheck with us often as companies continue to register for the fair and please see our upcoming scheduled events!\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003E2011 Biotech Career Fair\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Registration is open now for employers and students."}],"uid":"27195","created_gmt":"2011-09-01 10:09:46","changed_gmt":"2016-10-08 01:55:34","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-09-15T14:00:00-04:00","event_time_end":"2011-09-15T18:00:00-04:00","event_time_end_last":"2011-09-15T18:00:00-04:00","gmt_time_start":"2011-09-15 18:00:00","gmt_time_end":"2011-09-15 22:00:00","gmt_time_end_last":"2011-09-15 22:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/www.careerfair.bme.gatech.edu\/register.php","title":"Company registration"},{"url":"http:\/\/www.careerfair.bme.gatech.edu\/resume.php","title":"Student resume upload"},{"url":"http:\/\/www.careerfair.bme.gatech.edu\/","title":"Career Fair website"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"},{"id":"69452","name":"BBUGS"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}},"68636":{"#nid":"68636","#data":{"type":"event","title":"Buzz on Biotechnology High Open House","body":[{"value":"\u003Cp\u003EThe Buzz on Biotechnology High School Open House is open to all Atlanta area high school students, parents and teachers to come and learn about research in:\u003Cbr \/\u003E\u003Cstrong\u003E\u003Cbr \/\u003EBiomedical Engineering\u003Cbr \/\u003E\u003C\/strong\u003E\u003Cstrong\u003EChemistry\u003Cbr \/\u003E\u003C\/strong\u003E\u003Cstrong\u003EBiology\u003Cbr \/\u003E\u003C\/strong\u003E\u003Cstrong\u003ERegenerative Medicine\/Tissue Engineering\u003Cbr \/\u003E\u003C\/strong\u003E\u003Cstrong\u003EMechanical Engineering\u003Cbr \/\u003E\u003C\/strong\u003E\u003Cstrong\u003EMaterials Science \u0026amp; Engineering\u003Cbr \/\u003E\u003C\/strong\u003E\u003Cbr \/\u003EThe popular annual event, hosted by the Parker H. Petit Institute for Bioengineering and Bioscience and the Bioengineering and Bioscience Unified Graduate Students (BBUGS), is held for high school students to come and engage their interest in science and biotechnology. Students will be able to participate in interesting - and fun! - hands-on demonstrations, take tours of state-of-the-art Georgia Tech laboratories and attend short scientific seminars on a variety of biotechnology topics. \u0026nbsp;Visitors will even have an opportunity to talk with GT Admissions representatives who will be on hand for the event.\u003C\/p\u003E\n\u003Cp\u003E\u003Cbr \/\u003EFor complete event information and for FREE registration, visit the \u003Ca href=\u0022http:\/\/ibb.gatech.edu\/buzz-biotechnology\u0022\u003EBuzz on Biotechnology\u003C\/a\u003E website. \u0026nbsp;\u003Cbr \/\u003E\u003Cbr \/\u003EAttendance will be limited, so register today!\u003Cbr \/\u003E\u003Cbr \/\u003E\u0026nbsp;\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EBuzz on Biotechnology High Open House\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Open to all Atlanta area high school students"}],"uid":"27195","created_gmt":"2011-06-29 10:38:08","changed_gmt":"2016-10-08 01:55:13","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-10-22T11:00:00-04:00","event_time_end":"2011-10-22T14:00:00-04:00","event_time_end_last":"2011-10-22T14:00:00-04:00","gmt_time_start":"2011-10-22 15:00:00","gmt_time_end":"2011-10-22 18:00:00","gmt_time_end_last":"2011-10-22 18:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"hg_media":{"40002":{"id":"40002","type":"image","title":"Buzz","body":null,"created":"1449174136","gmt_created":"2015-12-03 20:22:16","changed":"1475894236","gmt_changed":"2016-10-08 02:37:16"}},"media_ids":["40002"],"related_links":[{"url":"http:\/\/www.ibb.gatech.edu\/","title":"Petit Institute for Bioengineering and Bioscience"},{"url":"http:\/\/www.ibb.gatech.edu\/buzz-biotechnology","title":"Buzz on Biotechnology website"},{"url":"http:\/\/bbugs.gatech.edu\/","title":"BBUGS website"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"4943","name":"BBUGS"},{"id":"13564","name":"Buzz on Biotechnology"},{"id":"5773","name":"High School Open House"},{"id":"248","name":"IBB"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:colly.mitchell@ibb.gatech.edu\u0022\u003EColly Mitchell\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"68963":{"#nid":"68963","#data":{"type":"event","title":"GaP Seminar Series","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EHyewon Lee\u003C\/strong\u003E\u0026nbsp;- Advisor, Hang Lu, PhD\u003Cbr \/\u003E\u003Cstrong\u003E\u003Cem\u003E\u0022\u003C\/em\u003E\u003C\/strong\u003E\u003Cstrong\u003E\u003Cem\u003EQuantitative Screening of C. elegans using Microfluidic Devices and Adaptive Algorithm\u0022\u003C\/em\u003E\u003C\/strong\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EForward genetic screening is a powerful tool to identify components in pathways in model organisms such as the nematode C. elegans. We use a single-layer microlfuidic device and quantitative analysis to screen a large number of animals in a high-throughput manner. This technology allows us to identify rare mutants that are difficult to find by eye. In a screen, we found many mutants that act to regulate tryptophan hydroxylase.\u0026nbsp;\u003Cbr \/\u003E\u003Cstrong\u003E\u003Cbr \/\u003ECatera Wilder\u003C\/strong\u003E - Advisor, Manu Platt, PhD\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003E\u003Cem\u003E\u0022Fight\nfor the Niche: Invasive Breast Cancer Cells Influence Msc Differentiation and\nSurvival in a Co-Culture Model\u0022\u003C\/em\u003E\u003C\/strong\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EWhen metastatic tumors reach the bone marrow the cancer cells will alter the microenvironment to promote their survival. Studies have shown a link between increased fatty bone marrow and a risk of cancer. The protease cathepsin K is associated with adipocyte differentiation and is upregulated in cancer. We hypothesized that cancer cells are promoting adipogenesis using cathepsin remodeling of the ECM as a mechanism to alter the microenvironment.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cbr \/\u003EThe Graduate and Post-Doc (GaP) Seminar Series is a weekly event of research presentations by two graduate students or post-docs conducting bio-related research.\u0026nbsp; The series is organized and sponsored by the Parker H. Petit Institute for Bioengineering and Bioscience (IBB) with additional support from the Wallace H. Coulter Department of Biomedical Engineering. It is held every Wednesday at 12:00pm in IBB 1128 and refreshments are provided. If your research group or department would like to present at future seminars, please contact Manu Platt, PhD at\u0026nbsp;\u003Ca href=\u0022mailto:manu.platt@bme.gatech.edu\u0022\u003Emanu.platt@bme.gatech.edu\u003C\/a\u003E.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EHyewon Lee and Catera Wilder presenting\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Hyewon Lee and Catera Wilder presenting"}],"uid":"27195","created_gmt":"2011-07-27 09:36:04","changed_gmt":"2016-10-08 01:55:18","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-11-30T11:00:00-05:00","event_time_end":"2011-11-30T12:00:00-05:00","event_time_end_last":"2011-11-30T12:00:00-05:00","gmt_time_start":"2011-11-30 16:00:00","gmt_time_end":"2011-11-30 17:00:00","gmt_time_end_last":"2011-11-30 17:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"hg_media":{"65807":{"id":"65807","type":"image","title":"GaP Seminar Series","body":null,"created":"1449176884","gmt_created":"2015-12-03 21:08:04","changed":"1475894582","gmt_changed":"2016-10-08 02:43:02","alt":"GaP Seminar Series","file":{"fid":"192409","name":"GaP_Logo_-_square.png","image_path":"\/sites\/default\/files\/images\/GaP_Logo_-_square_0.png","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/GaP_Logo_-_square_0.png","mime":"image\/png","size":9759,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/GaP_Logo_-_square_0.png?itok=xFPLw_YI"}},"71276":{"id":"71276","type":"image","title":"Hyewon Lee","body":null,"created":"1449177367","gmt_created":"2015-12-03 21:16:07","changed":"1475894632","gmt_changed":"2016-10-08 02:43:52","alt":"Hyewon Lee","file":{"fid":"193505","name":"hyewon_lee.jpg","image_path":"\/sites\/default\/files\/images\/hyewon_lee_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/hyewon_lee_0.jpg","mime":"image\/jpeg","size":22574,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/hyewon_lee_0.jpg?itok=fatX8U6y"}},"73070":{"id":"73070","type":"image","title":"Catera Wilder","body":null,"created":"1449177979","gmt_created":"2015-12-03 21:26:19","changed":"1475894671","gmt_changed":"2016-10-08 02:44:31","alt":"Catera Wilder","file":{"fid":"193725","name":"wilderc.jpg","image_path":"\/sites\/default\/files\/images\/wilderc_0.jpg","image_full_path":"http:\/\/www.tlwarc.hg.gatech.edu\/\/sites\/default\/files\/images\/wilderc_0.jpg","mime":"image\/jpeg","size":29779,"path_740":"http:\/\/www.tlwarc.hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/wilderc_0.jpg?itok=hNnYInl_"}}},"media_ids":["65807","71276","73070"],"related_links":[{"url":"http:\/\/www.ibb.gatech.edu\/gap-seminar-series","title":"GaP Seminar Series Schedule"},{"url":"http:\/\/www.ibb.gatech.edu\/","title":"Petit Institute for Bioengineering and Bioscience"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"13776","name":"Catera Wilder"},{"id":"12813","name":"GaP Seminar"},{"id":"248","name":"IBB"},{"id":"167524","name":"Sharon Hamilton"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EManu Platt, PhD\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"73092":{"#nid":"73092","#data":{"type":"event","title":"IBB Holiday Party","body":[{"value":"\u003Cp\u003EThe Parker H. Petit Institute for Bioengineering and Bioscience will hold its annual Holiday Party in the IBB atrium. Take a break from those offices and labs to come and celebrate the holiday season with the IBB community!\u003Cbr \/\u003E\u003Cbr \/\u003EThis event is open to all IBB faculty, staff, postdocs and graduate students. \u003Cstrong\u003E\u0026nbsp;RSVP required - deadline: Friday, December 2, 2011. \u003C\/strong\u003E\u003Cbr \/\u003E \u003Cbr \/\u003EVisit:  \u003Ca href=\u0022http:\/\/www.ibb.gatech.edu\/2011-ibb-holiday-party\u0022\u003E\u003Cstrong\u003EIBB Holiday Party RSVP\u003C\/strong\u003E\u003C\/a\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EIBB Holiday Party - Open to all IBB faculty, staff, post docs and graduate students\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Open to all IBB faculty, professional \u0026 research staff, postdocs, grad students and Petit Scholars - RSVP required"}],"uid":"27195","created_gmt":"2011-11-29 10:13:40","changed_gmt":"2016-10-08 01:56:45","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-12-06T15:00:00-05:00","event_time_end":"2011-12-06T17:00:00-05:00","event_time_end_last":"2011-12-06T17:00:00-05:00","gmt_time_start":"2011-12-06 20:00:00","gmt_time_end":"2011-12-06 22:00:00","gmt_time_end_last":"2011-12-06 22:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/ibb.gatech.edu\/2011-ibb-holiday-party","title":"RSVP"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"15168","name":"annual holiday party"},{"id":"248","name":"IBB"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:colly.mitchell@ibb.gatech.edu\u0022\u003EColly Mitchell\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}