Synthetic lectin mimics and their applications

Variations of glycosylation patterns in glycoproducts are often indicators of pathological changes.  Synthetic lectin mimics capable of selective recognition of carbohydrate biomarkers are potential diagnostics and important research tools in glycobiology. Based on the strong interactions between the boronic acid moiety and hydroxyl groups, we have developed a number of boronic acid-based lectin mimics. This presentation will discuss the synthesis and applications of these lectin mimics.

For more information contact Prof. Stefan France (404-385-1796).